The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Levels of serum granulocyte colony-stimulating factor in patients with infections
Open accessAbstract
To clarify the physiologic roles of granulocyte colony-stimulating factor (G-CSF) in infectious states in vivo, we examined the serum levels of G-CSF in patients with infection. Serum samples from 24 patients in the acute stage of infection (14 men and 10 women, age 65 to 101, without hematologic disorders), as well as samples from 32 age- matched normal elderly volunteers were investigated. Sixteen of the initial 24 patients were reexamined after the recovery phase. G-CSF levels were examined by quantitative enzyme immunoassay. The G-CSF level in normal elderly controls, 25.3 +/- 19.7 pg/mL, was not different from that reported in other findings. There was no statistically significant relationship between their G-CSF level and peripheral white blood cell count or neutrophilic granulocyte count. The G-CSF level in the acute stage of infection was 731.8 +/- 895.0 pg/mL, with a range of 30 to 3,199 pg/mL. There was no significant difference in G-CSF levels between patients with respiratory tract infection and those with urinary tract infection. In all 16 cases examined, the serum G-CSF level in the acute stage of infection was significantly higher than that after recovery phase, the latter being the same as the level in normal elderly controls. G-CSF must therefore play a significant role in human infectious states in vivo.
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Souza, L., Boone, T., Gabrilove, J., Lai, P., Zsebo, K., Murdock, D., Chazin, V., Bruszewski, J., Lu, H., Chen, K., et al. (1986) · Science · doi:10.1126/science.232.4746.61 · Cited by 1,266
Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor
Nagata, S., Tsuchiya, M., Asano, S., Kaziro, Y., Yamazaki, T., Yamamoto, O., Hirata, Y., Kubota, N., Oheda, M., Nomura, H., et al. (1986) · Nature · doi:10.1038/319415a0 · Cited by 812
Nicola, N. A., Metcalf, D., Matsumoto, M., & Johnson, G. R. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32158-6 · Cited by 555
Welte, K., Platzer, E., Lu, L., Gabrilove, J. L., Levi, E., Mertelsmann, R., & Moore, M. A. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.5.1526 · Cited by 517
Zucali, J. R., Dinarello, C. A., Oblon, D. J., Gross, M. A., Anderson, L., & Weiner, R. S. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112512 · Cited by 441
Watari, K., Asano, S., Shirafuji, N., Kodo, H., Ozawa, K., Takaku, F., & Kamachi, S. (1989) · Blood · doi:10.1182/blood.v73.1.117.117 · Cited by 354
Vascular endothelial cells and granulopoiesis: interleukin-1 stimulates release of G-CSF and GM-CSF
Zsebo, K., Yuschenkoff, V., Schiffer, S., Chang, D., McCall, E., Dinarello, C., Brown, M., Altrock, B., & Bagby, G. J. (1988) · Blood · doi:10.1182/blood.v71.1.99.99 · Cited by 273
Bagby, G. C., Dinarello, C. A., Wallace, P., Wagner, C., Hefeneider, S., & McCall, E. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112717 · Cited by 268
Cheers, C., Haigh, A. M., Kelso, A., Metcalf, D., Stanley, E. R., & Young, A. M. (1988) · Infection and Immunity · doi:10.1128/iai.56.1.247-251.1988 · Cited by 219
Independent regulation of M-CSF and G-CSF gene expression in human monocytes
Vellenga, E., Rambaldi, A., Ernst, T., Ostapovicz, D., & Griffin, J. (1988) · Blood · doi:10.1182/blood.v71.6.1529.1529 · Cited by 194
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Griffith, J. W., Sokol, C. L., & Luster, A. D. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120145 · Cited by 2,059
Lieschke, G., Grail, D., Hodgson, G., Metcalf, D., Stanley, E., Cheers, C., Fowler, K., Basu, S., Zhan, Y., & Dunn, A. (1994) · Blood · doi:10.1182/blood.v84.6.1737.1737 · Cited by 962
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Wood, A. J. J., Lieschke, G. J., & Burgess, A. W. (1992) · New England Journal of Medicine · doi:10.1056/nejm199207023270106 · Cited by 818
G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood
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Metadata
- Authors
- Kawakami, M., Tsutsumi, H., Kumakawa, T., Abe, H., Hirai, M., Kurosawa, S., Mori, M., & Fukushima, M.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 1990-11-15
- Volume
- 76
- Issue
- 10
- Pages
- 1962-1964
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W12954242
- Cited by
- 338
- References
- 12
- FWCI
- 4.59
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Kawakami, M., Tsutsumi, H., Kumakawa, T., Abe, H., Hirai, M., Kurosawa, S., Mori, M., & Fukushima, M. (1990). Levels of serum granulocyte colony-stimulating factor in patients with infections. Blood. https://doi.org/10.1182/blood.v76.10.1962.1962
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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