The DOI matches its Crossref record; 164 of the 164 references it cites were found in a registry or an index.
Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity
Abstract
The above story illustrates the translation of basic scientific discoveries to the clinic. In vitro and preclinical in vivo experimentation suggests that modulation of the B7:CD28 pathway will result in either amplification or suppression of the immune response. Considering the frequency with which diseases characterized by either inadequate or dysregulated immune function present to the practicing hematologist or oncologist, it is not difficult to envisage clinical applications for reagents that modulate this pathway. However, we still have much to learn about the function and clinical potential of this and other potentially redundant costimulatory pathways and therefore we suspect that this story will become considerably more complex over the next few years.
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Cites
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Mesenchymal stem cells avoid allogeneic rejection
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Dendritic Cell Vaccines for Cancer Immunotherapy
Timmerman, M., & Levy, M. (1999) · Annual Review of Medicine · doi:10.1146/annurev.med.50.1.507 · Cited by 485
Hancock, W. W., Sayegh, M. H., Zheng, X.-G., Peach, R., Linsley, P. S., & Turka, L. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.13967 · Cited by 411
CD40-CD40 Ligand: A Multifunctional Receptor-Ligand Pair
Van Kooten, C., & Banchereau, J. (1996) · Advances in Immunology · doi:10.1016/s0065-2776(08)60865-2 · Cited by 311
Role of Drug Disposition in Drug Hypersensitivity: A Chemical, Molecular, and Clinical Perspective
Park, B. K., Pirmohamed, M., & Kitteringham, N. R. (1998) · Chemical Research in Toxicology · doi:10.1021/tx980058f · Cited by 267
Metadata
- Authors
- Guinan, E., Gribben, J., Boussiotis, V., Freeman, G., & Nadler, L.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 1994-11-15
- Volume
- 84
- Issue
- 10
- Pages
- 3261-3282
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W1513609509
- Cited by
- 358
- References
- 164
- FWCI
- 13.48
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity. https://app.cochat.ai/papers/10.1182/blood.v84.10.3261.3261
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- Guinan, E., Gribben, J., Boussiotis, V., Freeman, G., & Nadler, L. (1994). Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity. Blood. https://doi.org/10.1182/blood.v84.10.3261.3261
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
