Recent trends in COPD prevalence in Spain: a repeated cross-sectional survey 1997-2007
Open accessAbstract
We aimed to describe changes in the prevalence of chronic obstructive pulmonary disease (COPD) in Spain by means of a repeated cross-sectional design comparing two population-based studies conducted 10 yrs apart. We compared participants from IBERPOC (Estudio epidemiológico de EPOC en España) (n = 4,030), conducted in 1997, with those of EPI-SCAN (Epidemiologic Study of COPD in Spain) (n = 3,802), conducted in 2007. Poorly reversible airflow obstruction compatible with COPD was defined according to the old European Respiratory Society definitions. COPD prevalence in the population between 40 to 69 yrs of age dropped from 9.1% (95% CI 8.1–10.2%) in 1997 to 4.5% (95% CI 2.4–6.6%), a 50.4% decline. The distribution of COPD prevalence by severity also changed from 38.3% mild, 39.7% moderate and 22.0% severe in 1997, to 85.6% mild, 13.0% moderate and 1.4% severe in 2007, and in the 40–69 yr EPI-SCAN sub-sample to 84.3% mild, 15.0% moderate and 0.7% severe. Overall, underdiagnosis was reduced from 78% to 73% (not a significant difference) and undertreatment from 81% to 54% (p<0.05) within this 10-yr frame. The finding of a substantial reduction in the prevalence of COPD in Spain is unexpected, as were the observed changes in the severity distribution, and highlights the difficulties in comparisons between repeated cross-sectional surveys of spirometry in the population.
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Cites
Vestbo, J., Hurd, S. S., Agustí, A. G., Jones, P. W., Vogelmeier, C., Anzueto, A., Barnes, P. J., Fabbri, L. M., Martinez, F. J., Nishimura, M., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201204-0596pp · Cited by 15,983 · see citing works
Miller, M. R., Hankinson, J., Brusasco, V., Burgos, F., Casaburi, R., Coates, A., Crapo, R., Enright, P., van der Grinten, C. P. M., Gustafsson, P., et al. (2005) · European Respiratory Journal · doi:10.1183/09031936.05.00034805 · Cited by 15,627 · see citing works
Murray, C. J. L., & López, A. D. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07492-2 · Cited by 7,007 · see citing works
Interpretative strategies for lung function tests
Pellegrino, R., Viegi, G., Brusasco, V., Crapo, R. O., Burgos, F., Casaburi, R., Coates, A., van der Grinten, C. P. M., Gustafsson, P., Hankinson, J., et al. (2005) · European Respiratory Journal · doi:10.1183/09031936.05.00035205 · Cited by 5,945 · see citing works
Lopez, A. D., Mathers, C. D., Ezzati, M., Jamison, D. T., & Murray, C. J. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68770-9 · Cited by 5,630 · see citing works
Lung volumes and forced ventilatory flows
Quanjer, P. H., Tammeling, G. J., Cotes, J. E., Pedersen, O. F., Peslin, R., & Yernault, J. (1993) · European Respiratory Journal · doi:10.1183/09041950.005s1693 · Cited by 5,484 · see citing works
Rabe, K. F., Hurd, S., Anzueto, A., Barnes, P. J., Buist, S. A., Calverley, P., Fukuchi, Y., Jenkins, C., Rodriguez-Roisin, R., van Weel, C., et al. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200703-456so · Cited by 4,925 · see citing works
Standardization of Spirometry — 1987 Update
Buist, A. S. (1987) · American Review of Respiratory Disease · doi:10.1164/ajrccm/136.5.1073 · Cited by 3,275 · see citing works
Buist, A. S., McBurnie, M. A., Vollmer, W. M., Gillespie, S., Burney, P., Mannino, D. M., Menezes, A. M., Sullivan, S. D., Lee, T. A., Weiss, K. B., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61377-4 · Cited by 2,364 · see citing works
Standardization of Spirometry—1987 Update
(1987) · American Review of Respiratory Disease · doi:10.1164/ajrccm/136.5.1285 · Cited by 2,322 · see citing works
Siafakas, N., Vermeire, P. A., Pride, N. B., Paoletti, P., Gibson, J., Howard, P., Yernault, J. C., Decramer, M., Higenbottam, T., Postma, D. S., et al. (1995) · European Respiratory Journal · doi:10.1183/09031936.95.08081398 · Cited by 1,583 · see citing works
The Global Burden of Chronic Diseases: Overcoming Impediments to Prevention and Control
Yach, D., Hawkes, C., Gould, C. L., & Hofman, K. J. (2004) · JAMA · doi:10.1001/jama.291.21.2616 · Cited by 1,369 · see citing works
The International Study of Asthma and Allergies in Childhood (ISAAC)
Asher, & Weiland (1998) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.1998.028s5052.x · Cited by 1,195 · see citing works
The Dutch Famine and Its Long-Term Consequences for Adult Health
Roseboom, T., de Rooij, S., & Painter, R. (2006) · Early Human Development · doi:10.1016/j.earlhumdev.2006.07.001 · Cited by 1,137 · see citing works
Menezes, A. M. B., Pérez‐Padilla, R., Jardim, J. R., Muiño, A., López, M. V., Valdivia, G. G., de, M. M., Tálamo, C., Hallal, P. C., & Victora, C. G. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67632-5 · Cited by 1,012 · see citing works
Barker, D. J., Godfrey, K. M., Fall, C., Osmond, C., Winter, P. D., & Shaheen, S. O. (1991) · BMJ · doi:10.1136/bmj.303.6804.671 · Cited by 889 · see citing works
Epidemiology and costs of chronic obstructive pulmonary disease
Chapman, K. R., Mannino, D. M., Soriano, J. B., Vermeire, P. A., Buist, A. S., Thun, M. J., Connell, C., Jemal, A., Lee, T. A., Miravitlles, M., et al. (2005) · European Respiratory Journal · doi:10.1183/09031936.06.00024505 · Cited by 699 · see citing works
Self-citationGeographic Variations in Prevalence and Underdiagnosis of COPD
Penña, V. S., Miravitlles, M., Gabriel, R., Jimenez-Ruiz, C. A., Villasante, C., Masa, J. F., Viejo, J. L., & Fernández-Fau, L. (2000) · CHEST Journal · doi:10.1378/chest.118.4.981 · Cited by 659 · see citing works
Self-citationLundbäck, B., Lindberg, A., LINDSTRÖM, M., Rönmark, E., Jonsson, A.-C., Jönsson, E., LARSSON, L.-G., ANDERSSON, S., Sandström, T., & LARSSON, K. (2003) · Respiratory Medicine · doi:10.1053/rmed.2003.1446 · Cited by 642 · see citing works
Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities
Miravitlles, M., Soriano, J. B., Rio, F. G., Muñoz, L., Duran‐Tauleria, E., Sánchez, G., Sobradillo, V., & Ancochea, J. (2009) · Thorax · doi:10.1136/thx.2009.115725 · Cited by 640 · see citing works
Self-citationSpirometric reference values from a Mediterranean population.
Roca, J., Sanchis, J., Agustí-Vidal, A., Segarra, F., Navajas, D., Rodríguez-Roisin, R., Casán, P., & Sans, S. (1986) · PubMed · Cited by 499 · see citing works
Björkstén, B., Clayton, T., Ellwood, P., Stewart, A., Strachan, D., & Phase III Study Group, T. I. (2008) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2007.00601.x · Cited by 401 · see citing works
Comparison of spirometry criteria for the diagnosis of COPD: results from the BOLD study
Vollmer, W. M., Gíslason, T., Burney, P., Enright, P., Gulsvik, A., Kocabaş, A., & Buist, A. S. (2009) · European Respiratory Journal · doi:10.1183/09031936.00164608 · Cited by 264 · see citing works
Epidemiology of childhood asthma
Sears, M. R. (1997) · The Lancet · doi:10.1016/s0140-6736(97)01468-2 · Cited by 263 · see citing works
Tuberculosis and airflow obstruction: evidence from the PLATINO study in Latin America
Menezes, A. M. B., Hallal, P. C., Pérez‐Padilla, R., Jardim, J. R., Muiño, A., López, M. V., Valdivia, G. G., de, M. M., Tálamo, C., Pertuze, J., et al. (2007) · European Respiratory Journal · doi:10.1183/09031936.00083507 · Cited by 254 · see citing works
Chronic obstructive pulmonary disease in the older adult: what defines abnormal lung function?
Mannino, D. M., Buist, A. S., & Vollmer, W. M. (2006) · Thorax · doi:10.1136/thx.2006.068379 · Cited by 250 · see citing works
Pearce, N. E., Sunyer, J., Cheng, S.-L., Chinn, S., Björkstén, B., Burr, M., Keil, U., ANDERSON, H. R., & Burney, P. (2000) · European Respiratory Journal · doi:10.1183/9031936.00.16337700 · Cited by 224 · see citing works
Pelkonen, M. K., Notkola, I.-L. K., Nissinen, A. M., Tukiainen, H. O., & Koskela, H. O. (2006) · CHEST Journal · doi:10.1378/chest.130.4.1129 · Cited by 203 · see citing works
Asthma prevalence in 1973, 1988 and 2003
Burr, M. L. (2006) · Thorax · doi:10.1136/thx.2005.045682 · Cited by 124 · see citing works
Ancochea, J., Badiola, C., Duran‐Tauleria, E., Rio, F. G., Miravitlles, M., Muñoz, L., Sobradillo, V., & Soriano, J. B. (2009) · Archivos de Bronconeumología · doi:10.1016/j.arbres.2008.06.001 · Cited by 93 · see citing works
Self-citationMiravitlles, M., Ferrer, M., Pont, À., Viejo, J. L., Masa, J. F., Gabriel, R., Jimenez-Ruiz, C. A., Villasante, C., Fernández-Fau, L., & Sobradillo, V. (2005) · Respiratory Medicine · doi:10.1016/j.rmed.2005.01.012 · Cited by 85 · see citing works
Self-citationLet's not forget: the GOLD criteria for COPD are based on post-bronchodilator FEV1
Sterk, P. J. (2004) · European Respiratory Journal · doi:10.1183/09031936.04.00017104 · Cited by 79 · see citing works
Use of spirometry and patterns of prescribing in COPD in primary care
Miravitlles, M., de la Roza, C., Naberán, K., Lamban, M., Gobartt, E., & Martín, A. (2007) · Respiratory Medicine · doi:10.1016/j.rmed.2007.02.019 · Cited by 77 · see citing works
Self-citationCOPD case finding by spirometry in high-risk customers of urban community pharmacies: A pilot study
Castillo, D., Guayta, R., Giner, J., et al. (2009) · Respiratory Medicine · doi:10.1016/j.rmed.2008.12.022 · Cited by 77 · see citing works
Definition of COPD: based on evidence or opinion?
Pellegrino, R., Brusasco, V., Viegi, G., et al. (2008) · European Respiratory Journal · doi:10.1183/09031936.00154307 · Cited by 49 · see citing works
Debating the definition of airflow obstruction: time to move on?
Miller, M. R., Pedersen, O. F., Pellegrino, R., & Brusasco, V. (2009) · European Respiratory Journal · doi:10.1183/09031936.00103309 · Cited by 43 · see citing works
Evaluation of the turbine pocket spirometer.
Gunawardena, K. A., Houston, K., & Smith, A. (1987) · Thorax · doi:10.1136/thx.42.9.689 · Cited by 42 · see citing works
Datos epidemiológicos de EPOC en España
Soriano, J. B., & Miravitlles, M. (2007) · Archivos de Bronconeumología · doi:10.1016/s0300-2896(07)71167-5 · Cited by 37 · see citing works
Self-citationJiménez-Ruíz, C. A., Miravitlles, M., Sobradillo, V., et al. (2004) · Nicotine & Tobacco Research · doi:10.1080/14622200410001727948 · Cited by 33 · see citing works
Self-citationHealth Burden and Funding at the Centers for Disease Control and Prevention
Curry, C. W., DE, A., Ikeda, R. M., & Thacker, S. A. (2006) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2005.10.028 · Cited by 25 · see citing works
Remember elephants and icebergs… “Your lung function should be here, but it is there!”
Soriano, J. B., & Parkes, G. (2009) · European Respiratory Journal · doi:10.1183/09031936.00001109 · Cited by 5 · see citing works
Self-citationEpidemiology of childhood asthma.
Burr, M. L. (1991) · PubMed · Cited by 5 · see citing works
Flagged first, then by citations
Research works printed but not linked: 4
- Comite ´Cientı ´fico del Estudio IBERPOC. El proyecto IBERPOC: Un estudio epidemiolo ´gico de la EPOC en Espan ˜a [Scientific Committee of the IBERPOC study. The IBERPOC project: an epidemiological study of COPD in Spain]. Arch Bronconeumol 1997; 33: 293-299.
- Ancochea J, Badiola C, Duran-Tauleria E, et al. The EPI-SCAN Study: A survey to assess the prevalence of chronic obstructive pulmonary disease in 40 to 80 year old in Spain: protocol summary. Arch Bronconeumol 2009; 45: 41-47.
- Siafakas NM, Vermeire P, Pride NB, et al. Optimal assessment and management of chronic obstructive pulmonary disease (COPD). Eur Respir J 1995; 8: 1398-1420.
- Buess CH, Boutellier U, Koller EA. Pneumotachometers. In: Webster JG, ed. Encyclopaedia of Medical Devices and Instrumentation. New York, Wiley, 1988; pp. 2319-2324.
Cited by
Sorted by citations
Wang, X., & Cheng, Z. (2020) · CHEST · doi:10.1016/j.chest.2020.03.012 · Cited by 2,214 · see citing works
- Authors
- Soriano, J. B., Ancochea, J., Miravitlles, M., García-Río, F., Duran-Tauleria, E., Muñoz, L., Jiménez-Ruiz, C. A., Masa, J. F., Viejo, J. L., Villasante, C., Fernández-Fau, L., Sánchez, G., & Sobradillo-Peña, V.
- Affiliations
- Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Hospital General Yagüe (ES)
- Hospital Universitario La Paz (ES)
- GlaxoSmithKline (Spain) (ES)
- Municipal Institute for Medical Research (ES)
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2009-12-08
- Volume
- 36
- Issue
- 4
- Pages
- 758-765
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2121230179
- Cited by
- 168
- References
- 42
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 3 · 2023: 5 · 2022: 7 · 2021: 9 · 2020: 18 · 2019: 11 · 2018: 11 · 2017: 11 · 2016: 8 · 2015: 18 · 2014: 9 · 2013: 15 · 2012: 15
- FWCI
- 10.10
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Respiratory Journal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- GlaxoSmithKline
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Keywords
- chronic obstructive pulmonary disease, COPD prevalence, temporal trends, Spain, airflow obstruction, underdiagnosis, undertreatment, spirometry
- MeSH terms
- Adult, Age Factors, Aged, Cross-Sectional Studies, Female, Geography, Humans, Lung Diseases, Male, Middle Aged, Sex Factors, Spain, Prevalence, Epidemiologic Studies, Pulmonary Disease, Chronic Obstructive
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