Cited by 463Chronic Obstructive Pulmonary Disease (COPD) ResearchCardiac Health and Mental HealthAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.

Depression and anxiety in patients with COPD

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Yohannes, Abebaw M., Alexopoulos, George S.·2014·European Respiratory Review

Abstract

Under-recognised and untreated depression and anxiety symptoms have deleterious effects on physical functioning and social interaction increasing fatigue and healthcare utilisation in patients with chronic obstructive pulmonary disease (COPD). Depression and anxiety are challenging to identify and treat because their symptoms often overlap with those of COPD. The cause(s) of depression and anxiety symptoms are multifactorial and include behavioural, social and biological factors. Less than one-third of COPD patients with comorbid depression or anxiety symptoms are receiving appropriate treatment. Factors that contribute to the lack of provision of treatment are varied, they include patient perceived barriers, for example lack of knowledge and reluctance to receive antidepressant drug therapy; poor treatment compliance and lack of a standardised diagnostic approach; and scarcity of adequate resources for mental health treatment. The evidence for the efficacy of antidepressant drug therapy in patients with COPD with comorbid depression and anxiety is inconclusive. There are some promising findings regarding pulmonary rehabilitation, psychological therapy and the collaborative care model in reducing depression and anxiety symptoms in patients with COPD, but these findings are limited by short-term follow-up periods. Further work is required to examine the efficacy of these interventions in randomised controlled trials with larger samples and long-term follow-up.

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Metadata

Authors
Yohannes, A. M., & Alexopoulos, G. S.
Affiliations
Manchester Metropolitan University (GB)
Corresponding author
Yohannes, Abebaw M.
Venue
European Respiratory Review
Published
2014-08-31
Volume
23
Issue
133
Pages
345-349
ISSN
  • 0905-9180 (ISSN-L)
  • 1600-0617
OpenAlex
W2122570705
Cited by
463
References
24
Citations by year
2026: 36 · 2025: 55 · 2024: 53 · 2023: 54 · 2022: 52 · 2021: 51 · 2020: 46 · 2019: 36 · 2018: 32 · 2017: 23 · 2016: 15 · 2015: 9 · 2014: 1
FWCI
12.81
Type
journal article
Language
en
Open access
Locations
  • European Respiratory Review (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
National Institute of Mental Health (R01MH076829, P30MH085943)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
chronic obstructive pulmonary disease, depression, anxiety, comorbidities, antidepressant treatment, barriers to treatment, medication adherence, pulmonary rehabilitation, psychotherapy, collaborative care, mental health services
MeSH terms
Anxiety, Depression, Humans, Pulmonary Disease, Chronic Obstructive

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