CoChat
Sign Up
Cited by 57Chronic Obstructive Pulmonary Disease (COPD) ResearchCardiac Health and Mental HealthAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Outcomes of depressed patients undergoing inpatient pulmonary rehabilitation

Alexopoulos, George S., Sirey, Jo Anne, Raue, Patrick J., Kanellopoulos, Dora, Clark, Timothy E., Novitch, Richard S.·2006·The American Journal of Geriatric Psychiatry
DOI 10.1097/01.jgp.0000199381.98971.d1
Open this paper in CoChat — free account

Abstract

Objective Approximately 30% of patients with chronic obstructive pulmonary disease (COPD) experience depression. Pulmonary rehabilitation for COPD focuses on physical conditioning, but includes behavioral interventions that may address depressive symptoms. This study tested the hypothesis that brief inpatient pulmonary rehabilitation is followed by improvement in both depressive symptoms and function in patients with COPD with major depression.Methods The subjects, who were recruited from the pulmonary rehabilitation unit of the Burke Rehabilitation Hospital in White Plains, NY, who had COPD and major depression were consecutively admitted patients to a pulmonary rehabilitation unit. Symptoms of depression, disability, medical burden, the experience of support, and satisfaction with treatment were systematically ascertained on admission and before discharge.Results Three hundred sixty-one patients were screened and 63 met criteria for COPD and major depression. Depressive symptoms improved by discharge (z = -6.785, p <0.0001); median length of stay was 16 days. Approximately 51% of subjects met criteria for response (50% or greater reduction in depressive symptoms scores from baseline), and 39% met criteria for remission (final Hamilton Depression scale score equal to or less than 10). History of treatment for depression was associated with limited change in depressive symptoms, whereas social support and satisfaction with treatment were predictors of improvement. All disability domains were lower at discharge compared to baseline (z = -3.928, p <0.0001). Subjects with pronounced disability at baseline had the greatest improvement if their depression improved by discharge.Conclusions Acute inpatient rehabilitation is followed by improvement of depressive symptoms and disability in older patients with COPD and major depression. Improvement of depression may be the result of behavioral interventions rather than the use of antidepressant drugs.

Integrity signals

Registry

Crossref · 10.1097/01.jgp.0000199381.98971.d1

Cites

44 of 44 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The only study of PR to address its effect on diagnosed major depression reported remission of depression in 39% of 63 inpatient program participants and clinically significant response in 51%.

    “However, the only study104 of PR to address its effect on diagnosed major depression reported remission of depression in 39% of 63 inpatient program participants and clinically significant response in 51%.”

    From Anxiety and Depression in COPD (2008) · cites this paper as [104]

  • In that study, subjects with pronounced disability at baseline had the greatest improvement if their depression improved by discharge.

    “Subjects with pronounced disability at baseline had the greatest improvement if their depression improved by discharge.”

    From Anxiety and Depression in COPD (2008) · cites this paper as [104]

  • The variable response among individuals to exercise training and the more limited response particularly in those with a history of depression treatment suggest a subgroup of COPD patients require specific psychological interventions beyond that offered as part of PR.

    “The variable response among individuals to exercise training and the more limited response particularly in those with a history of depression treatment104 suggest a subgroup of COPD patients require specific psychological interventions beyond that offered as part of PR.”

    From Anxiety and Depression in COPD (2008) · cites this paper as [104]

  • In that study, history of treatment for depression was associated with limited change in depressive symptoms, whereas social support and satisfaction with treatment were predictors of improvement.

    “History of treatment for depression was associated with limited change in depressive symptoms, whereas social support and satisfaction with treatment were predictors of improvement.”

    From Anxiety and Depression in COPD (2008) · cites this paper as [104]

  • The authors of that study concluded that acute inpatient rehabilitation is followed by improvement of depressive symptoms and disability in older patients with COPD and major depression.

    “The authors104 concluded that acute inpatient rehabilitation is followed by improvement of depressive symptoms and disability in older patients with COPD and major depression.”

    From Anxiety and Depression in COPD (2008) · cites this paper as [104]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Alexopoulos, G. S., Sirey, J. A., Raue, P. J., Kanellopoulos, D., Clark, T. E., & Novitch, R. S.
Affiliations
Cornell University (US)
Corresponding author
Raue, Patrick J.
ORCID
Venue
The American Journal of Geriatric Psychiatry
Publisher
Elsevier BV
Published
2006-05
Volume
14
Issue
5
Pages
466-475
ISSN
1064-7481 (ISSN-L)
DOI
10.1097/01.jgp.0000199381.98971.d1
OpenAlex
W2000906743
Cited by
57
References
44
Citations by year
2026: 1 · 2023: 2 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 1 · 2018: 3 · 2017: 5 · 2016: 4 · 2015: 3 · 2014: 6 · 2013: 3 · 2012: 2
FWCI
4.14
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • American Journal of Geriatric Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • U.S. Public Health Service (R01 HLB71992)
  • National Institute of Mental Health (P30MH068638, P30 MH68638)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
chronic obstructive pulmonary disease, depression, depressive symptoms, functional disability, social support, treatment satisfaction, behavioral interventions, older adults, treatment response and remission
MeSH terms
Aged, Depressive Disorder, Exercise Therapy, Female, Humans, Inpatients, Male, Oxygen Inhalation Therapy, Psychiatric Status Rating Scales, Respiratory Insufficiency, Severity of Illness Index, Social Support, Speech Therapy, Exercise, Treatment Outcome, Patient Satisfaction, Pulmonary Disease, Chronic Obstructive

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review