Personalised intervention for people with depression and severe COPD
Open accessAbstract
Summary: Chronic obstructive pulmonary disease (COPD) is often complicated by depression and exemplifies the challenge in managing chronic illnesses that require active patient participation in care. In a clinical trial (NCT00151372), we compared a novel personalised intervention for depression and COPD (PID-C) targeting treatment adherence with treatment as usual (TAU). In 138 patients with major depression and severe COPD, PID-C led to a higher remission rate and a greater reduction in depressive symptoms and in dyspnoea-related disability than TAU over 28 weeks and 6 months after the last session. If replicated, PID-C may serve as a care model for patients with both depression and medical illnesses with a deteriorating course.
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Personalized interventions aiming to increase adherence to treatment for major depression and COPD improved both depressive symptoms and disability.
“Personalized interventions aiming to increase adherence to treatment for major depression and COPD improved both depressive symptoms and disability165–167.”
From Mechanisms and treatment of late-life depression (2019) · cites this paper as [167]
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Mechanisms and treatment of late-life depression
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Mechanisms and treatment of late-life depression
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- Authors
- Alexopoulos, G. S., Kiosses, D. N., Sirey, J. A., Kanellopoulos, D., Novitch, R. S., Ghosh, S., Seirup, J. K., & Raue, P. J.
- Affiliations
- Cornell University (US)
- Burke Rehabilitation Hospital (US)
- Corresponding author
- Alexopoulos, George S.
- ORCID
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2013-03
- Volume
- 202
- Issue
- 3
- Pages
- 235-236
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- PMC
- PMC3585422
- OpenAlex
- W2164066892
- Cited by
- 35
- References
- 14
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 4 · 2022: 2 · 2021: 3 · 2019: 1 · 2018: 3 · 2017: 2 · 2016: 5 · 2015: 2 · 2014: 10 · 2013: 1
- FWCI
- 4.88
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (R01 HLB071992)
- National Institute of Mental Health (P30MH068638, R01MH076829, P30MH085943)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- depression, chronic obstructive pulmonary disease, personalized interventions, medication adherence, depression remission, comorbidities, patient participation in care
- MeSH terms
- Adult, Major Depressive Disorder, Dyspnea, Humans, Health Knowledge, Attitudes, Practice, Monte Carlo Method, Patient Compliance, Psychiatric Status Rating Scales, Remission Induction, Survival Analysis, Outcome Assessment, Health Care, Disease Progression, Pulmonary Disease, Chronic Obstructive, Intention to Treat Analysis
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