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Cited by 555

The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.

Pulmonary hypertension due to left heart disease

Open access
Vachiéry, Jean-Luc, Tedford, Ryan J., Rosenkranz, Stephan, Palazzini, Massimiliano, Lang, Irene, Guazzi, Marco, Coghlan, Gerry, Chazova, Irina, De Marco, Teresa·2019·European Respiratory Journal

Abstract

Pulmonary hypertension (PH) is frequent in left heart disease (LHD), as a consequence of the underlying condition. Significant advances have occurred over the past 5 years since the 5th World Symposium on Pulmonary Hypertension in 2013, leading to a better understanding of PH-LHD, challenges and gaps in evidence. PH in heart failure with preserved ejection fraction represents the most complex situation, as it may be misdiagnosed with group 1 PH. Based on the latest evidence, we propose a new haemodynamic definition for PH due to LHD and a three-step pragmatic approach to differential diagnosis. This includes the identification of a specific “left heart” phenotype and a non-invasive probability of PH-LHD. Invasive confirmation of PH-LHD is based on the accurate measurement of pulmonary arterial wedge pressure and, in patients with high probability, provocative testing to clarify the diagnosis. Finally, recent clinical trials did not demonstrate a benefit in treating PH due to LHD with pulmonary arterial hypertension-approved therapies.

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Metadata

Authors
Vachiéry, J.-L., Tedford, R. J., Rosenkranz, S., Palazzini, M., Lang, I., Guazzi, M., Coghlan, G., Chazova, I., & De Marco, T.
Venue
European Respiratory Journal
Published
2019-01
Volume
53
Issue
1
Pages
1801897
ISSN
  • 0903-1936 (ISSN-L)
  • 1399-3003
OpenAlex
W2904321847
Cited by
555
References
76
FWCI
38.21
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Pulmonary hypertension due to left heart disease. https://app.cochat.ai/papers/10.1183/13993003.01897-2018
The paper
Vachiéry, J.-L., Tedford, R. J., Rosenkranz, S., Palazzini, M., Lang, I., Guazzi, M., Coghlan, G., Chazova, I., & De Marco, T. (2019). Pulmonary hypertension due to left heart disease. European Respiratory Journal. https://doi.org/10.1183/13993003.01897-2018

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