Cited by 48

Artificial intelligence in thoracic surgery: past, present, perspective and limits

Etienne, Harry, Hamdi, Sarah, Le Roux, Marielle, Camuset, Juliette, Khalife-Hocquemiller, Theresa, Giol, Mihaela, Debrosse, Denis, Assouad, Jalal·2020·European Respiratory Review

Abstract

Artificial intelligence (AI) technology is becoming prevalent in many areas of everyday life. The healthcare industry is concerned by it even though its widespread use is still limited. Thoracic surgeons should be aware of the new opportunities that could affect their daily practice, by direct use of AI technology or indirect use via related medical fields (radiology, pathology and respiratory medicine). The objective of this article is to review applications of AI related to thoracic surgery and discuss the limits of its application in the European Union. Key aspects of AI will be developed through clinical pathways, beginning with diagnostics for lung cancer, a prognostic-aided programme for decision making, then robotic surgery, and finishing with the limitations of AI, the legal and ethical issues relevant to medicine. It is important for physicians and surgeons to have a basic knowledge of AI to understand how it impacts healthcare, and to consider ways in which they may interact with this technology. Indeed, synergy across related medical specialties and synergistic relationships between machines and surgeons will likely accelerate the capabilities of AI in augmenting surgical care.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1183/16000617.0010-2020

Cites

8 of 8 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • AI-powered imaging analysis and radiomics have improved detection and classification of pulmonary nodules, prediction of lymph node metastasis, and integration of molecular and radiomic features for non-invasive stratification.

    “AI-powered imaging analysis and radiomics have improved detection and classification of pulmonary nodules, prediction of lymph node metastasis, and integration of molecular and radiomic features for non-invasive stratification [4,5,6].”

    From Artificial Intelligence in Oncologic Thoracic Surgery: Clinical Decision Support and Emerging Applications (2026) · cites this paper as [5]

    The “Diagnostic for lung cancer” section reports AI-assisted detection and benign-versus-malignant classification of pulmonary nodules, including improved detection performance. It does not report prediction of lymph-node metastasis or integration of molecular and radiomic features for non-invasive stratification; searches for those terms found no supporting passage. (LLM, conf=0.87)

    Experimental — accuracy not yet measured
  • AI, particularly the Naive Bayes Classifier, is highly effective for predictive modeling.

    “Their findings support Chang et al.’s observation that AI, particularly the Naïve Bayes Classifier, is highly effective for predictive modeling.”

    From Artificial Intelligence in Oncologic Thoracic Surgery: Clinical Decision Support and Emerging Applications (2026) · cites this paper as [5]

    The “Prognostic-aided programme for decision-making” section reports promising predictive results for AI in thoracic surgery, including neural-network models. Our copy does not identify a Naïve Bayes Classifier or support the claim that it is particularly effective; searches for “Naive Bayes Classifier” and “Chang predictive modeling Bayes” found no such passage. Page numbers were unavailable. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • Etienne et al. reported successful applications of AI in predicting cardiorespiratory complications and postoperative prognosis in non-small-cell lung cancer patients.

    “Etienne et al. [5] reported successful applications of AI in predicting cardiorespiratory complications and postoperative prognosis in non-small-cell lung cancer patients.”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 43

  1. [1]Jiang F, Jiang Y, Zhi H, et al. Artificial intelligence in healthcare: past, present and future. Stroke Vasc Neurol 2017; 2: 230– 243. doi: 10.1136/svn-2017-000101 29507784 PMC5829945 · DOI · Paper page
  2. [3]McCarthy J, Minsky M, Rochester N, et al. A proposal for the Dartmouth Summer Research Project on artificial intelligence, August 31, 1955. AI Magazine 2006; 27: 12.
  3. [4]Niu JT W, Xu F, Zhou X, et al. Global research on artificial intelligence from 1990–2014: spatially-explicit bibliometric analysis. ISPRS Int J Geo-Inf 2016; 5: 66. doi: 10.3390/ijgi5050066 · DOI
  4. [5]Rotte KH, Meiske W. Results of computer-aided diagnosis of peripheral bronchial carcinoma. Radiology 1977; 125: 583– 586. doi: 10.1148/125.3.583 337350 · DOI
  5. [6]Rogers W, Ryack B, Moeller G. Computer-aided medical diagnosis: literature review. Int J Biomed Comput 1979; 10: 267– 289. doi: 10.1016/0020-7101(79)90001-1 385509 · DOI
  6. [7]Cummings SR, Lillington GA, Richard RJ. Estimating the probability of malignancy in solitary pulmonary nodules. A Bayesian approach. Am Rev Respir Dis 1986; 134: 449– 452. 3752700
  7. [8]Edwards FH, Schaefer PS, Callahan S, et al. Bayesian statistical theory in the preoperative diagnosis of pulmonary lesions. Chest 1987; 92: 888– 891. doi: 10.1378/chest.92.5.888 3311649 · DOI
  8. [9]Doi K, MacMahon H, Katsuragawa S, et al. Computer-aided diagnosis in radiology: potential and pitfalls. Eur J Radiol 1999; 31: 97– 109. doi: 10.1016/S0720-048X(99)00016-9 10565509 · DOI
  9. [10]Giger ML. Computerized analysis of images in the detection and diagnosis of breast cancer. Semin Ultrasound CT MR 2004; 25: 411– 418. doi: 10.1053/j.sult.2004.07.003 15559124 · DOI
  10. [11]Edwards FH, Schaefer PS, Cohen AJ, et al. Use of artificial intelligence for the preoperative diagnosis of pulmonary lesions. Ann Thorac Surg 1989; 48: 556– 559. doi: 10.1016/S0003-4975(10)66862-2 2679466 · DOI
  11. [12]Li Q, Li F, Suzuki K, et al. Computer-aided diagnosis in thoracic CT. Semin Ultrasound CT MR 2005; 26: 357– 363. doi: 10.1053/j.sult.2005.07.001 16274004 · DOI
  12. [14]Murphy A, Skalski M, Gaillard F. The utilisation of convolutional neural networks in detecting pulmonary nodules: a review. Br J Radiol 2018; 91: 20180028. doi: 10.1259/bjr.20180028 29869919 PMC6350496 · DOI
  13. [15]Nam JG, Park S, Hwang EJ, et al. Development and validation of deep learning-based automatic detection algorithm for malignant pulmonary nodules on chest radiographs. Radiology 2019; 290: 218– 228. doi: 10.1148/radiol.2018180237 30251934 · DOI · Paper page
  14. [16]National Lung Screening Trial Research Team, Aberle DR, Adams AM, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med 2011; 365: 395– 409. doi: 10.1056/NEJMoa1102873 21714641 PMC4356534 · DOI · Paper page
  15. [17]Horeweg N, van der Aalst CM, Thunnissen E, et al. Characteristics of lung cancers detected by computer tomography screening in the randomized NELSON trial. Am J Respir Crit Care Med 2013; 187: 848– 854. doi: 10.1164/rccm.201209-1651OC 23348977 · DOI
  16. [18]Ardila D, Kiraly AP, Bharadwaj S, et al. End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography. Nat Med 2019; 25: 954– 961. doi: 10.1038/s41591-019-0447-x 31110349 · DOI · Paper page
  17. [19]Brunelli A, Salati M, Rocco G, et al. European risk models for morbidity (EuroLung1) and mortality (EuroLung2) to predict outcome following anatomic lung resections: an analysis from the European Society of Thoracic Surgeons database. Eur J Cardiothorac Surg 2017; 51: 490– 497. doi: 10.1093/ejcts/ezx155 27744321 · DOI
  18. [20]Brunelli A, Charloux A, Bolliger CT, et al. ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy). Eur Respir J 2009; 34: 17– 41. doi: 10.1183/09031936.00184308 19567600 · DOI
  19. [21]Goldman L, Caldera DL, Nussbaum SR, et al. Multifactorial index of cardiac risk in noncardiac surgical procedures. N Engl J Med 1977; 297: 845– 850. doi: 10.1056/NEJM197710202971601 904659 · DOI
  20. [22]Torrington KG, Henderson CJ. Perioperative respiratory therapy (PORT). A program of preoperative risk assessment and individualized postoperative care. Chest 1988; 93: 946– 951. doi: 10.1378/chest.93.5.946 3359849 · DOI
  21. [23]Bellotti M, Elsner B, Paez De Lima A, et al. Neural networks as a prognostic tool for patients with non-small cell carcinoma of the lung. Mod Pathol 1997; 10: 1221– 1227. 9436967
  22. [24]Santos-Garcia G, Varela G, Novoa N, et al. Prediction of postoperative morbidity after lung resection using an artificial neural network ensemble. Artif Intell Med 2004; 30: 61– 69. doi: 10.1016/S0933-3657(03)00059-9 14684265 · DOI · Paper page
  23. [25]Esteva H, Marchevsky A, Nunez T, et al. Neural networks as a prognostic tool of surgical risk in lung resections. Ann Thorac Surg 2002; 73: 1576– 1581. doi: 10.1016/S0003-4975(02)03418-5 12022553 · DOI · Paper page
  24. [26]Yu KH, Zhang C, Berry GJ, et al. Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features. Nat Commun 2016; 7: 12474. doi: 10.1038/ncomms12474 27527408 PMC4990706 · DOI · Paper page
  25. [27]Coudray N, Ocampo PS, Sakellaropoulos T, et al. Classification and mutation prediction from non-small cell lung cancer histopathology images using deep learning. Nat Med 2018; 24: 1559– 1567. doi: 10.1038/s41591-018-0177-5 30224757 PMC9847512 · DOI · Paper page
  26. [28]Topalovic M, Das N, Janssens W. Artificial intelligence for pulmonary function test interpretation. Eur Respir J 2019; 53: 1801660. 31167887
  27. [29]Bendixen M, Jorgensen OD, Kronborg C, et al. Postoperative pain and quality of life after lobectomy via video-assisted thoracoscopic surgery or anterolateral thoracotomy for early stage lung cancer: a randomised controlled trial. Lancet Oncol 2016; 17: 836– 844. doi: 10.1016/S1470-2045(16)00173-X 27160473 · DOI
  28. [30]Falcoz PE, Puyraveau M, Thomas PA, et al. Video-assisted thoracoscopic surgery versus open lobectomy for primary non-small-cell lung cancer: a propensity-matched analysis of outcome from the European Society of Thoracic Surgeon database. Eur J Cardiothorac Surg 2016; 49: 602– 609. doi: 10.1093/ejcts/ezv154 25913824 · DOI
  29. [31]Hubbard FP. Sophisticated robots: balancing liability, regulation, and innovation. Florida Law Review 2014; 66: 1803– 1872.
  30. [32]Shademan A, Decker RS, Opfermann JD, et al. Supervised autonomous robotic soft tissue surgery. Sci Transl Med 2016; 8: 337ra364. doi: 10.1126/scitranslmed.aad9398 27147588 · DOI
  31. [33]Parikh RB, Teeple S, Navathe AS. Addressing bias in artificial intelligence in health care. JAMA 2019; 322: 2377– 2378. doi: 10.1001/jama.2019.18058 31755905 · DOI · Paper page
  32. [36]Youlden DR, Cramb SM, Baade PD. The International Epidemiology of Lung Cancer: geographical distribution and secular trends. J Thorac Oncol 2008; 3: 819– 831. doi: 10.1097/JTO.0b013e31818020eb 18670299 · DOI
  33. [38]Somashekhar SP, Sepúlveda M-J, Shortliffe EH, et al. A prospective blinded study of 1 000 cases analyzing the role of artificial intelligence: Watson for oncology and change in decision making of a Multidisciplinary Tumor Board (MDT) from a tertiary care cancer center. J Clin Oncol 2019; 37: Suppl. 15, 6533. doi: 10.1200/JCO.2019.37.15_suppl.6533 · DOI
  34. [39]Zhou N, Zhang C, Lv H. Concordance Study Between IBM Watson for Oncology and Clinical Practice for Patients With Cancer in China. Oncologist 2019; 24: 812– 819. 30181315 PMC6656482
  35. [41]Safavi KC, Khaniyev T, Copenhaver M, et al. Development and validation of a machine learning model to aid discharge processes for inpatient surgical care. JAMA Netw Open 2019; 2: e1917221. doi: 10.1001/jamanetworkopen.2019.17221 31825503 PMC6991195 · DOI
  36. [42]Simpkin AL, Schwartzstein RM. Tolerating uncertainty – the next medical revolution? N Engl J Med 2016; 375: 1713– 1715. doi: 10.1056/NEJMp1606402 27806221 · DOI
  37. [43]Topol EJ. High-performance medicine: the convergence of human and artificial intelligence. Nat Med 2019; 25: 44– 56. doi: 10.1038/s41591-018-0300-7 30617339 · DOI · Paper page
  38. [44]Keane PA, Topol EJ. With an eye to AI and autonomous diagnosis. NPJ Digit Med 2018; 1: 40. doi: 10.1038/s41746-018-0048-y 31304321 PMC6550235 · DOI · Paper page
  39. [49]Hwang TJ, Kesselheim AS, Vokinger KN. Lifecycle regulation of artificial intelligence and machined learning-based software devices in medicine. JAMA 2019; 322: 2285– 2286. 31755907
  40. [53]Wachter S, Mittelstadt B, Floridi L. Transparent, explainable, and accountable AI for robotics. Science Robotics 2017; 2: eaan6080. doi: 10.1126/scirobotics.aan6080 33157874 · DOI · Paper page
  41. [55]Veale M, Binns R, Van Kleek M. Some HCI priorities for GDPR-compliant machine learning. arXiv 2018; preprint [arXiv:1803.06174] arXiv:1803.06174. · arXiv
  42. [56]Vellido A. Societal issues concerning the application of artificial intelligence in medicine. Kidney Dis (Basel) 2019; 5: 11– 17. doi: 10.1159/000492428 30815459 PMC6388581 · DOI
  43. [58]Pesapane F, Volonte C, Codari M, et al. Artificial intelligence as a medical device in radiology: ethical and regulatory issues in Europe and the United States. Insights Imaging 2018; 9: 745– 753. doi: 10.1007/s13244-018-0645-y 30112675 PMC6206380 · DOI · Paper page

Authors
Etienne, H., Hamdi, S., Le Roux, M., Camuset, J., Khalife-Hocquemiller, T., Giol, M., Debrosse, D., & Assouad, J.
Venue
European Respiratory Review
Published
2020-08-18
Volume
29
Issue
157
Pages
200010
ISSN
  • 0905-9180
  • 1600-0617
Cited by
48
References
8
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review