The DOI matches its Crossref record; 223 of the 223 references it cites were found in a registry or an index.
A systematic review and meta-analysis of the effects of antibiotic consumption on antibiotic resistance
Open accessAbstract
BACKGROUND: Greater use of antibiotics during the past 50 years has exerted selective pressure on susceptible bacteria and may have favoured the survival of resistant strains. Existing information on antibiotic resistance patterns from pathogens circulating among community-based patients is substantially less than from hospitalized patients on whom guidelines are often based. We therefore chose to assess the relationship between the antibiotic resistance pattern of bacteria circulating in the community and the consumption of antibiotics in the community. METHODS: Both gray literature and published scientific literature in English and other European languages was examined. Multiple regression analysis was used to analyse whether studies found a positive relationship between antibiotic consumption and resistance. A subsequent meta-analysis and meta-regression was conducted for studies for which a common effect size measure (odds ratio) could be calculated. RESULTS: Electronic searches identified 974 studies but only 243 studies were considered eligible for inclusion by the two independent reviewers who extracted the data. A binomial test revealed a positive relationship between antibiotic consumption and resistance (p < .001) but multiple regression modelling did not produce any significant predictors of study outcome. The meta-analysis generated a significant pooled odds ratio of 2.3 (95% confidence interval 2.2 to 2.5) with a meta-regression producing several significant predictors (F(10,77) = 5.82, p < .01). Countries in southern Europe produced a stronger link between consumption and resistance than other regions. CONCLUSIONS: Using a large set of studies we found that antibiotic consumption is associated with the development of antibiotic resistance. A subsequent meta-analysis, with a subsample of the studies, generated several significant predictors. Countries in southern Europe produced a stronger link between consumption and resistance than other regions so efforts at reducing antibiotic consumption may need to be strengthened in this area. Increased consumption of antibiotics may not only produce greater resistance at the individual patient level but may also produce greater resistance at the community, country, and regional levels, which can harm individual patients.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“and a fast de-escalation was shown to be associated with a decreased risk [26, 27].”
From Lab efficiency and improvements in the management of bloodstream infections: a before and after study (2025) · cites this paper as [26]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Antibiotic resistance being correlated with antibiotic use, in terms of antimicrobial stewardship, it is crucial that antibiotics are only used when indicated”
From Lab efficiency and improvements in the management of bloodstream infections: a before and after study (2025) · cites this paper as [26]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
(2000) · Cited by 9,198
Outpatient antibiotic use in Europe and association with resistance: a cross-national database study
Goossens, H., Ferech, M., Vander Stichele, R., & Elseviers, M. (2005) · The Lancet · doi:10.1016/s0140-6736(05)17907-0 · Cited by 3,359
Self-citationMethicillin-Resistant S. aureus Infections among Patients in the Emergency Department
Moran, G. J., Krishnadasan, A., Gorwitz, R. J., Fosheim, G. E., McDougal, L. K., Carey, R. B., & Talan, D. A. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa055356 · Cited by 2,285
Costelloe, C., Metcalfe, C., Lovering, A., Mant, D., & Hay, A. D. (2010) · BMJ · doi:10.1136/bmj.c2096 · Cited by 1,981
The Relationship between Antimicrobial Use and Antimicrobial Resistance in Europe
Bronzwaer, S. L. A. M., Cars, O., Buchholz, U., Mölstad, S., Goettsch, W., Veldhuijzen, I. K., Kool, J. L., Sprenger, M. J. W., Degener, J. E., & System, P. I. T. E. A. R. S. (2002) · Emerging infectious diseases · doi:10.3201/eid0803.010192 · Cited by 691
Bacterial Resistance: Origins, Epidemiology, and Impact
Livermore, D. M. (2003) · Clinical Infectious Diseases · doi:10.1086/344654 · Cited by 589
Low Dosage and Long Treatment Duration of β-Lactam
Guillemot, D., Carbon, C., Balkau, B., Geslin, P., Lecoeur, H., Vauzelle-Kervroedan, F., Bouvenot, G., & Eschwège, É. (1998) · JAMA · doi:10.1001/jama.279.5.365 · Cited by 545
Malhotra‐Kumar, S., Lammens, C., Coenen, S., Herck, K. V., & Goossens, H. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60235-9 · Cited by 541
Self-citationArason, V. A., Kristinsson, K. G., Sigurdsson, J. A., Stefansdottir, G., Mölstad, S., & Gudmundsson, S. (1996) · BMJ · doi:10.1136/bmj.313.7054.387 · Cited by 493
Antimicrobial Drug Use and Resistance in Europe
van de Sande-Bruinsma, N., Grundmann, H., Verloo, D., Tiemersma, E. W., Monen, J., Goossens, H., Ferech, M., & the European Antimicrobial Resistance Surveillance System and European Surveillance of Antimicrobial Consumption Project Groups (2008) · Emerging infectious diseases · doi:10.3201/eid1411.070467 · Cited by 481
Self-citation
Cited by
Sorted by citations
Items 101–200 of 1,000
Adhikari, B., Pokharel, S., Raut, S., Adhikari, J., Thapa, S. S., Paudel, K., Narayan, G., Neupane, S., Neupane, S. R., Yadav, R. K., et al. (2021) · BMJ Global Health · doi:10.1136/bmjgh-2021-005829 · Cited by 72
Auranofin efficacy against MDRStreptococcus pneumoniaeandStaphylococcus aureusinfections
Aguinagalde, L., Díez‐Martínez, R., Yuste, J., Royo, I., Gil, C., Lasa, Í., Martín‐Fontecha, M., Marín‐Ramos, N. I., Ardanuy, C., Liñares, J., et al. (2015) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkv163 · Cited by 71
Niemirowicz, K., Piktel, E., Wilczewska, A. Z., Markiewicz, K. H., Durnaś, B., Wątek, M., Puszkarz, I., Wróblewska, M., Niklinska, W. E., Savage, P. B., et al. (2016) · International Journal of Nanomedicine · doi:10.2147/ijn.s113706 · Cited by 71
Qu, X. D., Yin, C., Sun, X., Huang, S., Li, C., Dong, P., Lu, X., Zhang, Z., & Ai-tian, Y. (2018) · PLoS ONE · doi:10.1371/journal.pone.0196668 · Cited by 71
Determinants of antibiotic prescribing among doctors in a Nigerian urban tertiary hospital
Ogunleye, O. O., Fadare, J. O., Yinka-Ogunleye, A. F., Paramadhas, B. D. A., & Godman, B. (2018) · Hospital Practice · doi:10.1080/21548331.2018.1475997 · Cited by 71
CON: COVID-19 will not result in increased antimicrobial resistance prevalence
Collignon, P., & Beggs, J. J. (2020) · JAC-Antimicrobial Resistance · doi:10.1093/jacamr/dlaa051 · Cited by 70
Community pharmacists—Leaders for antibiotic stewardship in respiratory tract infection
Essack, S. Y., Bell, J. A., & Shephard, A. (2017) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/jcpt.12650 · Cited by 69
Time trends and geographical variation in prescribing of antibiotics in England 1998–2017
Curtis, H. J., Walker, A. J., Mahtani, K. R., & Goldacre, B. M. (2018) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dky377 · Cited by 69
Appropriateness of Surgical Antimicrobial Prophylaxis Practices in Australia
Ierano, C., Thursky, K., Marshall, C. L., Koning, S. I., James, R. S., Johnson, S. A. S., Imam, N., Worth, L. J., & Peel, T. N. (2019) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.15003 · Cited by 68
Martinez-Sobalvarro, J. V., Pereira-Júnior, A. A., Pereira, L. B., Baldoni, A. O., Ceron, C. S., & dos Reis, T. M. (2021) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-021-01358-4 · Cited by 70
Yamasaki, D., Tanabe, M., Muraki, Y., Kato, G., Ohmagari, N., & Yagi, T. (2017) · Infection · doi:10.1007/s15010-017-1097-x · Cited by 68
Luchen, C. C., Chibuye, M., Spijker, R., Simuyandi, M., Chisenga, C. C., Bosomprah, S., Chilengi, R., Schultsz, C., Mende, D. R., & Harris, V. (2023) · PLoS Medicine · doi:10.1371/journal.pmed.1004235 · Cited by 74
Rasschaert, G., Elst, D. V., Colson, L., Herman, L., Ferreira, H. C. D. C., Dewulf, J., Decrop, J., Meirlaen, J., Heyndrickx, M., & Daeseleire, E. (2020) · Antibiotics · doi:10.3390/antibiotics9010034 · Cited by 66
la Martire, G., Robin, C., Oubaya, N., Lepeule, R., Beckerich, F., Leclerc, M., Barhoumi, W., Toma, A., Pautas, C., Maury, S., et al. (2018) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-018-3328-1 · Cited by 65
Vaughn, V. M., Gandhi, T. N., Conlon, A., Chopra, V., Malani, A. N., & Flanders, S. A. (2018) · Clinical Infectious Diseases · doi:10.1093/cid/ciy1102 · Cited by 65
Ferreira, I. M., Beisken, S., Lüftinger, L., Weinmaier, T., Klein, M., Bacher, J., Patel, R., von Haeseler, A., & Posch, A. E. (2020) · Journal of Clinical Microbiology · doi:10.1128/jcm.00273-20 · Cited by 66
Current Antibiotic Use Among Hospitals in the sub-Saharan Africa Region; Findings and Implications
Siachalinga, L., Godman, B., Mwita, J. C., Sefah, I. A., Ogunleye, O. O., Massele, A. Y., & Lee, I. (2023) · Infection and Drug Resistance · doi:10.2147/idr.s398223 · Cited by 64
Jeffs, L. P., McIsaac, W. J., Zahradnik, M., Senthinathan, A., Dresser, L., McIntyre, M. T., Tannenbaum, D., Bell, C. M., & Morris, A. M. (2020) · PLoS ONE · doi:10.1371/journal.pone.0223822 · Cited by 63
Truong, R., Tang, V., Grennan, T., & Tan, D. H. S. (2022) · JAC-Antimicrobial Resistance · doi:10.1093/jacamr/dlac009 · Cited by 63
Goddard, J. C., & Janssen, D. A. W. (2017) · International Urogynecology Journal · doi:10.1007/s00192-017-3508-z · Cited by 63
Martino, M. D., Lallo, A., Kirchmayer, U., Davoli, M., & Fusco, D. (2017) · BMC Public Health · doi:10.1186/s12889-017-4905-4 · Cited by 63
Evolution of drug resistance in an antifungal-naive chronic Candida lusitaniae infection
Demers, E. G., Biermann, A. R., Masonjones, S., Crocker, A. W., Ashare, A., Stajich, J., & Hogan, D. A. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1807698115 · Cited by 63
Schwartz, K. L., Ivers, N. M., Langford, B. J., Taljaard, M., Neish, D., Brown, K. A., Leung, V., Daneman, N., Alloo, J., Silverman, M. E., et al. (2021) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2021.2790 · Cited by 62
Luiken, R. E. C., Heederik, D. J. J., Scherpenisse, P., Gompel, L. V., van Heijnsbergen, E., Greve, G. D., Gortemaker, B. G. M., Tersteeg‐Zijderveld, M. H. G., Fischer, J., Juraschek, K., et al. (2022) · Environmental Research · doi:10.1016/j.envres.2022.112715 · Cited by 62
Bassetti, M., Welte, T., & Wunderink, R. G. (2016) · Critical Care · doi:10.1186/s13054-016-1197-5 · Cited by 62
Complications related to induced abortion: a combined retrospective and longitudinal follow-up study
Carlsson, I., Breding, K., & Larsson, P.-G. (2018) · BMC Women s Health · doi:10.1186/s12905-018-0645-6 · Cited by 62
Current prescribing trends of antibiotics by dentists in Australia from 2013 to 2016. Part 1.
Teoh, L., Stewart, K., Mariño, R., & McCullough, M. J. (2018) · Australian Dental Journal · doi:10.1111/adj.12622 · Cited by 61
Carracedo‐Martínez, E., Gonzalez-Gonzalez, C., Rodrigues, A. T., Prego-Domínguez, J., Takkouche, B., Herdeiro, M. T., & Figueiras, A. (2019) · Clinical Therapeutics · doi:10.1016/j.clinthera.2019.01.018 · Cited by 61
Gilham, E. L., Pearce-Smith, N., Carter, V., & Ashiru-Oredope, D. (2024) · BMC Public Health · doi:10.1186/s12889-024-17766-w · Cited by 60
Antibiotic consumption and resistance of gram-negative pathogens (collateral damage)
Čižman, M., & Srovin, T. P. (2018) · Europe PMC (PubMed Central) · doi:10.3205/id000040 · Cited by 60
Effect of Point-of-Care Testing for Respiratory Pathogens on Antibiotic Use in Children
Mattila, S., Paalanne, N., Honkila, M., Pokka, T. M.-L., & Tapiainen, T. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.16162 · Cited by 60
Li, X., Mowlaboccus, S., Jackson, B., Cai, C., & Coombs, G. W. (2024) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2024.107251 · Cited by 64
MacLean, R. C., & Vogwill, T. (2014) · Evolution Medicine and Public Health · doi:10.1093/emph/eou032 · Cited by 65
A review and meta-analysis of Staphylococcus aureus prevalence in foods
Léguillier, V., Pinamonti, D., Chang, C.-M., Gunjan, Mukherjee, R., Himanshu, Cossettini, A., Manzano, M., Anba‐Mondoloni, J., Malet-Villemagne, J., et al. (2024) · The Microbe · doi:10.1016/j.microb.2024.100131 · Cited by 66
Zhang, Z., Morgan, C. E., Bonomo, R. A., & Yu, E. W. (2021) · mBio · doi:10.1128/mbio.01031-21 · Cited by 58
Babatola, A. O., Fadare, J. O., Olatunya, O. S., Obiako, R., Enwere, O. O., Kalungia, A. C., Ojo, T. O., Sunmonu, T., Desalu, O. O., & Godman, B. (2020) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2021.1829474 · Cited by 58
Rahman, S., & Hollis, A. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1170426 · Cited by 58
Bakhit, M., Hoffmann, T., Scott, A. M., Beller, E., Rathbone, J., & Mar, C. D. (2018) · BMC Medicine · doi:10.1186/s12916-018-1109-4 · Cited by 58
Prevalence Of Self-Medication With Antibiotics Among Residents In United Arab Emirates
Abduelkarem, A. R., Othman, A. M., Abuelkhair, Z. R., Ghazal, M. M., Alzouobi, S. B., & Zowalaty, M. E. E. (2019) · Infection and Drug Resistance · doi:10.2147/idr.s224720 · Cited by 57
Alshammari, M. K., Ramadan, M., Haif, H., Abdullah, B., Mubarak, J., Ahmad, W., Mari, S., Hassan, S., Eid, R., Hasan, M. Y., et al. (2023) · Antibiotics · doi:10.3390/antibiotics12101504 · Cited by 59
RetractedQuorum Sensing: Not Just a Bridge Between Bacteria
Liu, D., Lu, Y., Li, Z., Pang, X., & Gao, X. (2025) · MicrobiologyOpen · doi:10.1002/mbo3.70016 · Cited by 60
Chang, J., Lv, B., Zhu, S., Yu, J., Zhang, Y., Ye, D., Aziz, M. M., Yang, C., & Fang, Y. (2018) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2018.1425616 · Cited by 57
Relationship between Antibiotic Consumption and Resistance: A Systematic Review
Abejew, A. A., Wubetu, G. Y., & Fenta, T. G. (2024) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2024/9958678 · Cited by 56
Inappropriate Diagnosis of Pneumonia Among Hospitalized Adults
Gupta, A. B., Flanders, S. A., Petty, L. A., Gandhi, T. N., Pulia, M. S., Horowitz, J. K., Ratz, D., Bernstein, S. J., Malani, A. N., Patel, P., et al. (2024) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2024.0077 · Cited by 58
Hong, Y., Li, H., Chen, L., Su, H., Zhang, B., Luo, Y. H., Li, C., Zhao, Z., Shao, Y., & Guo, L. (2024) · Microbiome · doi:10.1186/s40168-024-01795-z · Cited by 58
Spread of hospital-acquired infections: A comparison of healthcare networks
Nekkab, N., Astagneau, P., Temime, L., & Crépey, P. (2017) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005666 · Cited by 56
Garza-Cervantes, J. A., Mendiola-Garza, G., de Melo, E. M., Dugmore, T. I. J., Matharu, A. S., & Morones‐Ramírez, J. R. (2020) · Scientific Reports · doi:10.1038/s41598-020-64127-9 · Cited by 56
The role of “spillover” in antibiotic resistance
Olesen, S. W., Lipsitch, M., & Grad, Y. H. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2013694117 · Cited by 55
Høgli, J. U., Garcia, B. H., Skjold, F., Skogen, V., & Småbrekke, L. (2016) · BMC Infectious Diseases · doi:10.1186/s12879-016-1426-1 · Cited by 55
Dalhoff, A. (2020) · Infection · doi:10.1007/s15010-020-01536-y · Cited by 60
Yang, Y., Chen, L., Ke, X., Mao, Z., & Zheng, B. (2021) · BMC Health Services Research · doi:10.1186/s12913-021-06698-5 · Cited by 55
Chotiprasitsakul, D., Srichatrapimuk, S., Kirdlarp, S., Pyden, A., & Santanirand, P. (2019) · Infection and Drug Resistance · doi:10.2147/idr.s192540 · Cited by 54
Addressing resistance to antibiotics in systematic reviews of antibiotic interventions
Leibovici, L., Paul, M., Garner, P., Sinclair, D., Afshari, A., Pace, N. L., Cullum, N. A., Williams, H. C., Smyth, A. R., Skoetz, N., et al. (2016) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkw135 · Cited by 54
Bakhit, M., Mar, C. D., Gibson, E. M., & Hoffmann, T. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-026735 · Cited by 54
Obolski, U., Lourenço, J., Thompson, C., Thompson, R. N., Gori, A., & Gupta, S. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1718712115 · Cited by 54
McGettigan, P., Roderick, P., Kadam, A., & Pollock, A. (2019) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.13503 · Cited by 53
Arya, S., Williams, A. D., Reina, S. V., Knapp, C. W., Kreft, J., Hobman, J. L., & Stekel, D. J. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.116602 · Cited by 55
Momand, P., Becktor, J. P., Naimi‐Akbar, A., Tobin, G., & Götrick, B. (2022) · Clinical Implant Dentistry and Related Research · doi:10.1111/cid.13068 · Cited by 53
Garau, J., Dp, N., Wullt, B., & Bassetti, M. (2014) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2014.08.002 · Cited by 53
Bianco, A., Papadopoli, R., Mascaro, V., Pileggi, C., & Pavía, M. (2018) · Infection and Drug Resistance · doi:10.2147/idr.s170349 · Cited by 53
Treatments of trimethylaminuria: where we are and where we might be heading
Schmidt, A. C., & Leroux, J. (2020) · Drug Discovery Today · doi:10.1016/j.drudis.2020.06.026 · Cited by 55
Ogoina, D., Iliyasu, G., Kwaghe, V., Otu, A. A., Akase, I. E., Adekanmbi, O. A., Dalhat, M., Iroezindu, M., Aliyu, S., Oyeyemi, A. S., et al. (2021) · Antimicrobial Resistance and Infection Control · doi:10.1186/s13756-021-00940-9 · Cited by 52
Sadowska‐Klasa, A., Piekarska, A., Prejzner, W., Bieniaszewska, M., & Hellmann, A. R. (2017) · Annals of Hematology · doi:10.1007/s00277-017-3205-5 · Cited by 52
Gatta, L., Scarpignato, C., Fiorini, G., Belsey, J., Saracino, I. M., Ricci, C., & Vaira, D. (2018) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14597 · Cited by 52
Garza-Cervantes, J. A., Escárcega‐González, C. E., Barriga‐Castro, E. D., Mendiola-Garza, G., Marichal‐Cancino, B. A., López-Vázquez, M. A., & Morones‐Ramírez, J. R. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s196470 · Cited by 52
Ogunlana, L., Kaur, D., Shaw, L. P., Jangir, P. K., Walsh, T. R., Uphoff, S., & MacLean, R. C. (2023) · The ISME Journal · doi:10.1038/s41396-023-01509-7 · Cited by 51
Is There Evidence to Support Probiotic Use for Healthy People?
Merenstein, D. J., Tancredi, D. J., Karl, J. P., Krist, A. H., Lenoir‐Wijnkoop, I., Reid, G., Roos, S., Szajewska, H., & Sanders, M. E. (2024) · Advances in Nutrition · doi:10.1016/j.advnut.2024.100265 · Cited by 54
Public knowledge, attitudes and behaviour towards antibiotic usage in Windhoek, Namibia
Pereko, D., Lubbe, M. S., & Essack, S. Y. (2015) · Southern African Journal of Infectious Diseases · doi:10.1080/23120053.2015.1107290 · Cited by 51
Defensive medicine among antibiotic stewards: the international ESCMID AntibioLegalMap survey
Tebano, G., Dyar, O. J., Beovič, B., Béraud, G., Thilly, N., Pulcini, C., & ESCMID Study Group for Antimicrobial stewardshiP (ESGAP) (2018) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dky098 · Cited by 51
Antimicrobial resistance and over the counter use of drugs in Nepal
Pokharel, S., & Adhikari, B. (2020) · Journal of Global Health · doi:10.7189/jogh.10.010360 · Cited by 51
Worldwide comparison of treatment guidelines for sore throat
Coutinho, G., Duerden, M. G., Sessa, A., Barradas, S. C., & Altiner, A. (2020) · International Journal of Clinical Practice · doi:10.1111/ijcp.13879 · Cited by 50
Soni, K., Jyoti, K., Chandra, H., & Chandra, R. (2022) · Bioresource Technology Reports · doi:10.1016/j.biteb.2022.101080 · Cited by 53
Abbott, I. J., Peel, T. N., Cairns, K. A., & Stewardson, A. J. (2022) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2022.05.016 · Cited by 51
van Bijnen, E. M., Paget, J., Klerk, E. S. M. D. L., den Heijer, C. D. J., Versporten, A., Stobberingh, E. E., Goossens, H., & Schellevis, F. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135094 · Cited by 50
Self-citationMegeus, V., Nilsson, K., Karlsson, J., Eriksson, B. I., & Andersson, A. E. (2015) · Antimicrobial Resistance and Infection Control · doi:10.1186/s13756-015-0042-y · Cited by 50
Park, J., Han, E., Lee, S. O., & Kim, D. (2017) · PLoS ONE · doi:10.1371/journal.pone.0177435 · Cited by 50
A Systematic Review of Antimicrobial Stewardship Interventions in the Emergency Department
Losier, M., Ramsey, T., Wilby, K. J., & Black, E. (2017) · Annals of Pharmacotherapy · doi:10.1177/1060028017709820 · Cited by 51
Simões, A. S., Maia, M. R., Gregório, J., Couto, I., Asfeldt, A. M., Simonsen, G. S., Póvoa, P. M. S. R., Viveiros, M., & Lapão, L. V. (2018) · Journal of Hospital Infection · doi:10.1016/j.jhin.2018.07.034 · Cited by 50
Huygens, J., Rasschaert, G., Heyndrickx, M., Dewulf, J., Coillie, E. V., Quataert, P., Daeseleire, E., & Becue, I. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.153518 · Cited by 50
Cheng, V. C., Wong, S. C., Ho, P., & Yuen, K. (2015) · Emerging Microbes & Infections · doi:10.1038/emi.2015.8 · Cited by 49
Outpatient Antibiotic Prescribing Among United States Nurse Practitioners and Physician Assistants
Sanchez, G. V., Hersh, A. L., Shapiro, D. J., Cawley, J. F., & Hicks, L. A. (2016) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofw168 · Cited by 49
Screening for STIs in PrEP cohorts results in high levels of antimicrobial consumption
Kenyon, C. R., Baetselier, I. D., & Wouters, K. (2020) · International Journal of STD & AIDS · doi:10.1177/0956462420957519 · Cited by 49
McDonnell, L., Armstrong, D., Ashworth, M. J., Dregan, A., Malik, U., & White, P. T. (2017) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkx248 · Cited by 48
Aliabadi, S., Anyanwu, P. E., Beech, E., Jauneikaite, E., Wilson, P., Hope, R., Majeed, A., Müller‐Pebody, B., & Costelloe, C. (2021) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(21)00069-4 · Cited by 48
Cartuliares, M. B., Rosenvinge, F. S., Mogensen, C. B., Skovsted, T. A., Andersen, S. L., Østergaard, C., Pedersen, A. K., & Skjøt‐Arkil, H. (2023) · PLoS Medicine · doi:10.1371/journal.pmed.1004314 · Cited by 48
Predictors and variability of antibiotic prescribing amongst family physicians
Schwartz, K. L., Brown, K. A., Etches, J., Langford, B. J., Daneman, N., Tu, K., Johnstone, J., Achonu, C., & Garber, G. E. (2019) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkz112 · Cited by 48
Abubakar, U., & Tangiisuran, B. (2019) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2019.10.007 · Cited by 48
Stanton, I. C., Bethel, A. C., Leonard, A. F. C., Gaze, W. H., & Garside, R. (2020) · Environmental Evidence · doi:10.1186/s13750-020-00197-6 · Cited by 48
Antimicrobial Stewardship in the Neonatal Intensive Care Unit: An Update
Gkentzi, D., & Dimitriou, G. (2019) · Current Pediatric Reviews · doi:10.2174/1573396315666190118101953 · Cited by 47
Zartab, S., Abbasian, H., Hajimolaali, M., & Yektadoost, A. (2019) · Journal of Research in Pharmacy Practice · doi:10.4103/jrpp.jrpp_19_42 · Cited by 47
Zheng, S., Matzneller, P., Zeitlinger, M. A., & Schmidt, S. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02904-14 · Cited by 46
Prescribing patterns of dental practitioners in Australia from 2001 to 2012. Antimicrobials
Ford, P. J., Saladine, C., Zhang, K., & Hollingworth, S. (2016) · Australian Dental Journal · doi:10.1111/adj.12427 · Cited by 46
Versporten, A., Gyssens, I. C., Pulcini, C., Monnier, A. A., Schouten, J. A., Milanič, R., Benić, M. S., Tebano, G., Maréchal, M. L., Zanichelli, V., et al. (2018) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dky119 · Cited by 46
Self-citationSynthesis and Preclinical Evaluation of TPA-Based Zinc Chelators as Metallo-β-lactamase Inhibitors
Schnaars, C., Kildahl‐Andersen, G., Prandina, A., Popal, R., Radix, S., Borgne, M. L., Gjøen, T., Andresen, A. M. S., Heikal, A., Økstad, O. A., et al. (2018) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.8b00137 · Cited by 46
Holmes, E. A. F., Harris, S. D., Hughes, A., Craine, N., & Hughes, D. A. (2018) · Antibiotics · doi:10.3390/antibiotics7040106 · Cited by 46
O’Doherty, J., Leader, L. F., O’Regan, A., Dunne, C. P., Puthoopparambil, S. J., & O’Connor, R. (2019) · BMC Family Practice · doi:10.1186/s12875-019-0917-8 · Cited by 46
Hagiya, H., Kokado, R., Ueda, A., Okuno, H., Morii, D., Hamaguchi, S., Yamamoto, N., Yoshida, H., & Tomono, K. (2019) · Internal Medicine · doi:10.2169/internalmedicine.2603-18 · Cited by 46
Al-Jayyousi, G. F., Abdel‐Rahman, M. E., El‐Heneidy, A., Kurdi, R., & Faisal, E. (2019) · PLoS ONE · doi:10.1371/journal.pone.0225499 · Cited by 46
Khan, F. U., Khan, F. U., Hayat, K., Ahmad, T., Khan, A., Chang, J., Malik, U. R., Khan, Z., Lambojon, K., & Fang, Y. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18031320 · Cited by 48
Malek, N. A. N. N., & Ramli, N. I. (2015) · Applied Clay Science · doi:10.1016/j.clay.2015.03.007 · Cited by 46
Metadata
- Authors
- Bell, B. G., Schellevis, F., Stobberingh, E., Goossens, H., & Pringle, M.
- Affiliations
- University of Nottingham (GB)
- Maastricht University (NL)
- University of Antwerp (BE)
- Corresponding author
- Bell, Brian G
- Venue
- BMC Infectious Diseases
- Published
- 2014-01-09
- Volume
- 14
- Issue
- 1
- Pages
- 13-13
- ISSN
- 1471-2334 (ISSN-L)
- PMC
- PMC3897982
- OpenAlex
- W2064618548
- Cited by
- 1,262
- References
- 223
- Citations by year
- 2026: 56 · 2025: 91 · 2024: 151 · 2023: 151 · 2022: 149 · 2021: 156 · 2020: 158 · 2019: 105 · 2018: 93 · 2017: 60 · 2016: 50 · 2015: 27 · 2014: 13
- FWCI
- 7.04
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Infectious Diseases (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research Publications (Maastricht University) (publishedVersion, cc-by)
- Pure Amsterdam UMC (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Research Publications (Maastricht University) (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- European Commission (223083)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antibiotic Use and Resistance
- Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
- Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
- Keywords
- antibiotic use, antibiotic resistance, community-acquired infections, antimicrobial resistance patterns, selection pressure, Southern Europe, regional variation in resistance
- MeSH terms
- Anti-Bacterial Agents, Drug Resistance, Microbial, Europe, Humans, Odds Ratio
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
