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Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell marker

Schneider, Meike, Huber, Johannes, Hadaschik, Boris, Siegers, Gabrielle M, Fiebig, Heinz-Herbert, Schüler, Julia·2012·BMC Cancer
DOI 10.1186/1471-2407-12-96PMC PMC3368744
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Figure 1 Antigen expression in the colon carcinoma panel. Mean expression of CD133, CD24, CD44, CDCP1 and CXCR4 in the colon carcinoma cell line panel (black bars) and the corresponding xenograft panel (grey bars).
Figure 1 Antigen expression in the colon carcinoma panel. Mean expression of CD133, CD24, CD44, CDCP1 and CXCR4 in the colon carcinoma cell line panel (black bars) and the corresponding xenograft panel (grey bars).CC BY · PubMed Central
Figure 2 Expression of 5 different surface markers on a panel of human colon carcinoma cell lines.
Figure 2 Expression of 5 different surface markers on a panel of human colon carcinoma cell lines.CC BY · PubMed Central
Figure 3 Expression of 5 different surface markers on a panel of human colon carcinoma xenografts.
Figure 3 Expression of 5 different surface markers on a panel of human colon carcinoma xenografts.CC BY · PubMed Central
Figure 4 Mean percentage of double- and triple-positive cells within the CD133+ subpopulation of xenografts.
Figure 4 Mean percentage of double- and triple-positive cells within the CD133+ subpopulation of xenografts.CC BY · PubMed Central
Figure 5 In vivo growth behaviour study of SW620 cells. Growth behaviour of 1 × 105 CD133+, CD133- and unsorted SW620 colon carcinoma cells injected subcutaneously in NOD/SCID mice.
Figure 5 In vivo growth behaviour study of SW620 cells. Growth behaviour of 1 × 105 CD133+, CD133- and unsorted SW620 colon carcinoma cells injected subcutaneously in NOD/SCID mice.CC BY · PubMed Central
Figure 6 Immunohistochemistry (IHC) of different SW620 cell fractions. CD133 expression in xenografts that grew out of unsorted, CD133+ and CD133- subclones of SW620 colon carcinoma cells. A: IHC α-hu CD133: SW620 unsorted cells injected subcutaneously (sc) in NOD/SCID mice. B: IHC α-hu CD133: SW620 CD133+ cells injected sc in NOD/SCID mice. C: IHC α-hu CD133: SW620 CD133- cells injected sc in NOD/SCID mice.
Figure 6 Immunohistochemistry (IHC) of different SW620 cell fractions. CD133 expression in xenografts that grew out of unsorted, CD133+ and CD133- subclones of SW620 colon carcinoma cells. A: IHC α-hu CD133: SW620 unsorted cells injected subcutaneously (sc) in NOD/SCID mice. B: IHC α-hu CD133: SW620 CD133+ cells injected sc in NOD/SCID mice. C: IHC α-hu CD133: SW620 CD133- cells injected sc in NOD/SCID mice.CC BY · PubMed Central

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Metadata

Authors
Schneider, M., Huber, J., Hadaschik, B., Siegers, G. M., Fiebig, H.-H., & Schüler, J.
Venue
BMC Cancer
Publisher
Springer Science and Business Media LLC
Published
2012-03-20
Volume
12
Issue
1
ISSN
1471-2407
DOI
10.1186/1471-2407-12-96
PMC
PMC3368744
Cited by
75
References
1
Language
en
Licence
www.springer.com/tdm (unspecified)

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