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Compliance with continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea among privately paying patients- a cross sectional study
Open accessAbstract
BACKGROUND: To evaluate the compliance, benefits and side effects associated with continuous positive airway pressure (CPAP) therapy among Pakistani patients treated for obstructive sleep apnea (OSA) in private sector. METHODS: Patients diagnosed to have OSA based on overnight study who were recommended for CPAP therapy, between 1998 and 2003, were evaluated by telephonic survey and review of hospital notes. Compliance, benefits and side effects associated with CPAP therapy were assessed. RESULTS: Out of 135 patients who were prescribed CPAP therapy, 75 could be contacted. Sixty (80%) started using CPAP within one month of diagnosis and 46 (61%) continued to use it long-term (beyond one year). Compliance with CPAP therapy was associated with higher body mass index, higher Epworth sleepiness scale score, history of witnessed apnea, and reduction in daytime sleepiness with CPAP therapy. OSA severity as assessed by apnea-hypopnea index did not affect compliance with CPAP therapy. Use of anti-depressants and CPAP induced sleep disturbances were associated with poor compliance with CPAP therapy. CONCLUSIONS: Obesity, excessive daytime sleepiness, witnessed apnea and improvement of daytime symptoms following use of CPAP were predictors of improved compliance. Use of antidepressants and CPAP induced sleep disturbances were predictors of poor compliance.
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CPAP adherence shows a significant reduction in long-term follow-up, estimated at around 50% until the end of the first year.
“its adherence shows a significant reduction in long-term follow-up, being estimated at around 50% until the end of the first year, according to several studies.”
From Role of Nasal Surgery in Adult Obstructive Sleep Apnea: A Systematic Review (2024) · cites this paper as [23]
The Results report that 80% started CPAP within one month and 61.3% continued beyond one year, supporting lower long-term use. They do not establish a statistically significant decline or an adherence estimate of around 50% at the end of the first year. (LLM, conf=0.87)
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Metadata
- Authors
- Hussain, S. F., Irfan, M., Waheed, Z., Alam, N., Mansoor, S., & Islam, M.
- Affiliations
- Kettering General Hospital (GB)
- Aga Khan University (PK)
- Armed Forces Hospital Southern Region (SA)
- Aga Khan University Hospital (PK)
- Corresponding author
- Irfan, Muhammad
- Venue
- BMC Pulmonary Medicine
- Published
- 2014-11-29
- Volume
- 14
- Issue
- 1
- Pages
- 188-188
- ISSN
- 1471-2466 (ISSN-L)
- PMC
- PMC4258250
- OpenAlex
- W2083585752
- Cited by
- 55
- References
- 34
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 7 · 2023: 2 · 2022: 5 · 2021: 3 · 2020: 2 · 2019: 6 · 2018: 12 · 2017: 7 · 2016: 5 · 2015: 2
- FWCI
- 3.11
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Pulmonary Medicine (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- eCommons - AKU (Aga Khan University) (submittedVersion)
- Greater South Information System
- Topics
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Keywords
- obstructive sleep apnea, CPAP therapy, medication adherence, predictors of compliance, body mass index, daytime sleepiness, witnessed apnea, antidepressants, CPAP side effects, sleep disorders, apnea-hypopnea index, Pakistani patients, private sector
- MeSH terms
- Aged, Cross-Sectional Studies, Female, Humans, Disorders of Excessive Somnolence, Male, Middle Aged, Pakistan, Patient Compliance, Severity of Illness Index, Body Mass Index, Hospitals, Private, Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
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