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Cited by 261

The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.

Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine

Open access
Levine, Myron M·2010·BMC Biology

Abstract

Oral vaccines, whether living or non-living, viral or bacterial, elicit diminished immune responses or have lower efficacy in developing countries than in developed countries. Here I describe studies with a live oral cholera vaccine that include older children no longer deriving immune support from breast milk or maternal antibodies and that identify some of the factors accounting for the lower immunogenicity, as well as suggesting counter-measures that may enhance the effectiveness of oral immunization in developing countries. The fundamental breakthrough is likely to require reversing effects of the 'environmental enteropathy' that is often present in children living in fecally contaminated, impoverished environments.

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Metadata

Authors
Levine, M. M.
Venue
BMC Biology
Published
2010-10-04
Volume
8
Issue
1
Pages
129-129
ISSN
1741-7007 (ISSN-L)
OpenAlex
W2075558699
Cited by
261
References
98
FWCI
10.72
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine. https://app.cochat.ai/papers/10.1186/1741-7007-8-129
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Levine, M. M. (2010). Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine. BMC Biology. https://doi.org/10.1186/1741-7007-8-129

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.