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Cited by 326Rheumatoid Arthritis Research and TherapiesSex and Gender in HealthcareAutoimmune and Inflammatory Disorders Research

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Sex differences in rheumatoid arthritis: more than meets the eye

Open access
van Vollenhoven, Ronald F·2009·BMC Medicine
DOI 10.1186/1741-7015-7-12PMC PMC2670321
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Abstract

Sex differences in the prevalence of autoimmune diseases such as rheumatoid arthritis (RA) are well described, but the literature is not as clear about sex differences in RA disease course and prognosis. A recent study from a very large cross-sectional international cohort demonstrated slightly worse levels of disease activity and function in female patients with RA, compared with men. These findings are discussed in the context of our evolving knowledge of sex differences in the expression of this prototypic autoimmune disease, both in terms of the actual disease activity level, the effects that the disease has on physical function, and our ability accurately to measure these aspects.

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Crossref · 10.1186/1741-7015-7-12

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Figure 1 X-linked genetic factors, hormonal factors, and exposures that may be different for men and women could all influence the prevalence of autoimmune diseases as well as their severity. The latter aspect is, however, also influenced by many more factors, including differences in the treatments given, the response to treatments, the subjective experience of the disease, and the instruments used to measure the disease. The thick arrows indicate established associations and the thin arrows putative associations.
Figure 1 X-linked genetic factors, hormonal factors, and exposures that may be different for men and women could all influence the prevalence of autoimmune diseases as well as their severity. The latter aspect is, however, also influenced by many more factors, including differences in the treatments given, the response to treatments, the subjective experience of the disease, and the instruments used to measure the disease. The thick arrows indicate established associations and the thin arrows putative associations.CC BY · PubMed Central

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Research works printed but not linked: 1

  1. Joelsson J, Van Vollenhoven RF: RA: different for her than for him? – Gender differences in RA therapeutics. Oral presentation, International Congress on Gender Medicine. 2008

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Metadata

Authors
van Vollenhoven, R. F.
Venue
BMC Medicine
Publisher
Springer Science and Business Media LLC
Published
2009-03-30
Volume
7
Issue
1
Pages
12-12
ISSN
1741-7015 (ISSN-L)
DOI
10.1186/1741-7015-7-12
PMC
PMC2670321
OpenAlex
W2090929542
Cited by
326
References
33
Citations by year
2026: 22 · 2025: 23 · 2024: 35 · 2023: 33 · 2022: 38 · 2021: 43 · 2020: 39 · 2019: 31 · 2018: 25 · 2017: 9 · 2016: 6 · 2015: 5 · 2014: 5 · 2013: 1 · 2012: 5
FWCI
2.59
Type
journal article
Language
en
Open access
Licence
Locations
  • BMC Medicine (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
  • Health Sciences › Medicine › Hematology › Autoimmune and Inflammatory Disorders Research
Keywords
rheumatoid arthritis, sex differences, disease activity, physical function, prognosis, autoimmune disease, clinical course, sex differences in disease expression
MeSH terms
Arthritis, Rheumatoid, Cross-Sectional Studies, Female, Humans, Male, Severity of Illness Index, Sex Characteristics, Cohort Studies, Prevalence

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