Development of the lateral ventricular choroid plexus in a marsupial, Monodelphis domestica
Open accessAbstract
BACKGROUND: Choroid plexus epithelial cells are the site of blood/cerebrospinal fluid (CSF) barrier and regulate molecular transfer between the two compartments. Their mitotic activity in the adult is low. During development, the pattern of growth and timing of acquisition of functional properties of plexus epithelium are not known. METHODS: Numbers and size of choroid plexus epithelial cells and their nuclei were counted and measured in the lateral ventricular plexus from the first day of its appearance until adulthood. Newborn Monodelphis pups were injected with 5-bromo-2-deoxyuridine (BrdU) at postnatal day 3 (P3), P4 and P5. Additional animals were injected at P63, P64 and P65. BrdU-immunopositive nuclei were counted and their position mapped in the plexus structure at different ages after injections. Double-labelling immunocytochemistry with antibodies to plasma protein identified post-mitotic cells involved in protein transfer. RESULTS: Numbers of choroid plexus epithelial cells increased 10-fold between the time of birth and adulthood. In newborn pups each consecutive injection of BrdU labelled 20-40 of epithelial cells counted. After 3 injections, numbers of BrdU positive cells remained constant for at least 2 months. BrdU injections at an older age (P63, P64, P65) resulted in a smaller number of labelled plexus cells. Numbers of plexus cells immunopositive for both BrdU and plasma protein increased with age indicating that protein transferring properties are acquired post mitotically. Labelled nuclei were only detected on the dorsal arm of the plexus as it grows from the neuroependyma, moving along the structure in a 'conveyor belt' like fashion. CONCLUSIONS: The present study established that lateral ventricular choroid plexus epithelial cells are born on the dorsal side of the structure only. Cells born in the first few days after choroid plexus differentiation from the neuroependyma remain present even two months later. Protein-transferring properties are acquired post-mitotically and relatively early in plexus development.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Bulk profiling indicates that each ChP retains a developmental blueprint of its origins along the body axis, with ventricle-specific transcriptomes and secretomes for the lateral and 4th ventricle ChPs.
“Bulk profiling of whole tissue (Liddelow et al., 2010; Lun et al., 2015b; Silva-Vargas et al., 2016) or sorted subpopulations (Lun et al., 2015b) indicates that each ChP retains a developmental blueprint of its origins along the body axis, with ventricle-specific transcriptomes and secretomes for the lateral and 4th ventricle ChPs (Lun et al., 2015a).”
From A cellular and spatial map of the choroid plexus across brain ventricles and ages (2021) · cites this paper as Liddelow et al., 2010
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898 · see citing works
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
Altman, J., & Das, G. D. (1965) · Journal of Comparative Neurology · doi:10.1002/cne.901240303 · Cited by 3,592 · see citing works
JUNCTIONS BETWEEN INTIMATELY APPOSED CELL MEMBRANES IN THE VERTEBRATE BRAIN
Brightman, M., & Reese, T. S. (1969) · The Journal of Cell Biology · doi:10.1083/jcb.40.3.648 · Cited by 2,457 · see citing works
A principle for counting tissue structures on random sections
Weibel, E. R., & Gómez, D. M. (1962) · Journal of Applied Physiology · doi:10.1152/jappl.1962.17.2.343 · Cited by 837 · see citing works
Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development
Furuta, Y., Piston, D. W., & Hogan, B. L. M. (1997) · Development · doi:10.1242/dev.124.11.2203 · Cited by 710 · see citing works
Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres
Xuan, S., Baptista, C., Balas, G., Tao, W., Soares, V. C., & Lai, E. (1995) · Neuron · doi:10.1016/0896-6273(95)90262-7 · Cited by 603 · see citing works
Physiology of the CSF and Blood-Brain Barriers
Davson, H., & Segal, M. B. (1996) · Medical Entomology and Zoology · Cited by 576 · see citing works
Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development
Porter, F. D., Drago, J., Xu, Y., Cheema, S. S., Wassif, C. A., Huang, S.-P., Lee, E., Grinberg, A., Massalas, J. S., Bodine, D. M., et al. (1997) · Development · doi:10.1242/dev.124.15.2935 · Cited by 491 · see citing works
Sequential actions of BMP receptors control neural precursor cell production and fatePreprint
Panchision, D. M., Pickel, J. M., Studer, L., Lee, S., Turner, P. A., Hazel, T. G., & McKay, R. D. G. (2001) · Genes & Development · doi:10.1101/gad.894701 · Cited by 327 · see citing works
Patterning of the Dorsal Telencephalon and Cerebral Cortex by a Roof Plate-Lhx2 Pathway
Monuki, E. S., Porter, F. D., & Walsh, C. A. (2001) · Neuron · doi:10.1016/s0896-6273(01)00504-9 · Cited by 294 · see citing works
Keep, R. F., & Jones, H. C. (1990) · Developmental Brain Research · doi:10.1016/0165-3806(90)90163-s · Cited by 257 · see citing works
BMP Signaling Is Required Locally to Pattern the Dorsal Telencephalic Midline
Hébert, J. M., Mishina, Y. M., & McConnell, S. K. (2002) · Neuron · doi:10.1016/s0896-6273(02)00900-5 · Cited by 256 · see citing works
Barriers in the brain: a renaissance?
Saunders, N. R., Ek, C. J., Habgood, M. D., & Dzięgielewska, K. M. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.03.003 · Cited by 226 · see citing works
Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation
Awatramani, R., Soriano, P., Rodriguez, C., Mai, J. J., & Dymecki, S. M. (2003) · Nature Genetics · doi:10.1038/ng1228 · Cited by 215 · see citing works
Imayoshi, I., Shimogori, T., Ohtsuka, T., & Kageyama, R. (2008) · Development · doi:10.1242/dev.021535 · Cited by 190 · see citing works
The choroid plexus: A historical review
Dohrmann, G. J. (1970) · Brain Research · doi:10.1016/0006-8993(70)90324-0 · Cited by 175 · see citing works
Rickert, C. H., & Paulus, W. (2000) · Microscopy Research and Technique · doi:10.1002/1097-0029(20010101)52:1 · Cited by 160 · see citing works
Barriers in the Immature Brain
Saunders, N. R., Knott, G. W., & Dzięgielewska, K. M. (2000) · Cellular and Molecular Neurobiology · doi:10.1023/a:1006991809927 · Cited by 156 · see citing works
Actual problems of the cerebrospinal fluid-contacting neurons
Béla, V. I. G. H., & Vigh‐Teichmann, I. (1998) · Microscopy Research and Technique · doi:10.1002/(sici)1097-0029(19980401)41:1 · Cited by 151 · see citing works
Direct and indirect roles of CNS dorsal midline cells in choroid plexus epithelia formation
Currle, D. S., Cheng, X., Hsu, C.-M., & Monuki, E. S. (2005) · Development · doi:10.1242/dev.01915 · Cited by 123 · see citing works
Proteins in cerebrospinal fluid and plasma of fetal rats during development
Dzięgielewska, K. M., Evans, C. A. N., Lai, P. C. W., Lorscheider, F. L., Malinowska, D. H., Møllgrd, K., & Saunders, N. R. (1981) · Developmental Biology · doi:10.1016/s0012-1606(81)80024-3 · Cited by 121 · see citing works
Møllgård, K., Jacobsen, M., Jacobsen, G. K., CLAUSEN, P. P., & Saunders, N. R. (1979) · Neuroscience Letters · doi:10.1016/0304-3940(79)95349-7 · Cited by 116 · see citing works
A morphological study of the development of the mouse choroid plexus.
Rr, S. (1979) · PubMed · Cited by 110 · see citing works
Efflux transport systems for organic anions and cations at the blood?CSF barrier
Kusuhara, H., & Sugiyama, Y. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.07.007 · Cited by 106 · see citing works
Habgood, M. D., Sedgwick, J. E. C., Dzięgielewska, K. M., & Saunders, N. R. (1992) · The Journal of Physiology · doi:10.1113/jphysiol.1992.sp019332 · Cited by 105 · see citing works
Incorporation of Unnatural Pyrimidine Bases into Deoxyribonucleic Acid of Mammalian Cells
Eidinoff, M. L., Cheong, L., & Rich, M. A. (1959) · Science · doi:10.1126/science.129.3362.1550 · Cited by 105 · see citing works
Fernandes, M., Gutin, G., Alcorn, H. L., McConnell, S. K., & Hébert, J. M. (2007) · Development · doi:10.1242/dev.004325 · Cited by 102 · see citing works
Blood—cerebrospinal fluid transfer of plasma proteins during fetal development in the sheep
Dzięgielewska, K. M., Evans, C. A. N., Malinowska, D. H., Møllgård, K., Reynolds, M. L., & Saunders, N. R. (1980) · The Journal of Physiology · doi:10.1113/jphysiol.1980.sp013172 · Cited by 96 · see citing works
Fine structure of the developing telencephalic and myelencephalic choroid plexus in the rabbit
Tennyson, V. M., & Pappas, G. D. (1964) · The Journal of Comparative Neurology · doi:10.1002/cne.901230307 · Cited by 94 · see citing works
Ek, C. J., Habgood, M. D., Dzięgielewska, K. M., & Saunders, N. R. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10661 · Cited by 92 · see citing works
Msx1is required for dorsal diencephalon patterning
Bach, A., Lallemand, Y., Nicola, M., Ramos, C., Mathis, L., Maufras, M., & Robert, B. (2003) · Development · doi:10.1242/dev.00609 · Cited by 90 · see citing works
Blood–CSF barrier function in the rat embryo
Johansson, P. A., Dzięgielewska, K. M., Ek, C. J., Habgood, M. D., Liddelow, S. A., Potter, A., Stolp, H. B., & Saunders, N. R. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04904.x · Cited by 87 · see citing works
Hunter, N. L., & Dymecki, S. M. (2007) · Development · doi:10.1242/dev.003095 · Cited by 83 · see citing works
Morphology of the roof plate of the forebrain and the lateral choroid plexuses in the human embryo
Bailey, P. (1916) · The Journal of Comparative Neurology · doi:10.1002/cne.900260104 · Cited by 73 · see citing works
A possible transepithelial pathway via endoplasmic reticulum in foetal sheep choroid plexus
Møllgård, K., & Saunders, N. R. (1977) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1977.0142 · Cited by 71 · see citing works
An experimental and ultrastructural study on the development of the avian choroid plexus
Wilting, J., & Christ, B. (1989) · Cell and Tissue Research · doi:10.1007/bf00218783 · Cited by 59 · see citing works
Choroid plexus ependymal cells host neural progenitor cells in the rat
Itokazu, Y., Kitada, M., Dezawa, M., Mizoguchi, A., Matsumoto, N., Shimizu, A., & Idé, C. (2005) · Glia · doi:10.1002/glia.20255 · Cited by 52 · see citing works
Cellular transfer of macromolecules across the developing choroid plexus of Monodelphis domestica
Liddelow, S. A., Dzięgielewska, K. M., Ek, C. J., Johansson, P. A., Potter, A., & Saunders, N. R. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06571.x · Cited by 51 · see citing works
Albumin transfer across the choroid plexus of South American opossum (Monodelphis domestica).
Knott, G. W., Dzięgielewska, K. M., Habgood, M. D., Li, Z. S., & Saunders, N. R. (1997) · The Journal of Physiology · doi:10.1113/jphysiol.1997.sp021919 · Cited by 51 · see citing works
Thomas, T., & Dziadek, M. A. (1993) · Development · doi:10.1242/dev.117.1.253 · Cited by 49 · see citing works
Jacobsen, M., Jacobsen, G. K., CLAUSEN, P. P., Saunders, N. R., & Møllgård, K. (1982) · Developmental Brain Research · doi:10.1016/0165-3806(82)90025-6 · Cited by 37 · see citing works
Intercellular barriers to and transcellular transfer of albumin in the fetal sheep brain
Balslev, Y., Dzięgielewska, K. M., Møllgård, K., & Saunders, N. R. (1997) · Anatomy and Embryology · doi:10.1007/s004290050042 · Cited by 33 · see citing works
Speake, T., & Brown, P. D. N. (2004) · Brain Research · doi:10.1016/j.brainres.2004.01.034 · Cited by 28 · see citing works
Dzięgielewska, K. M., Habgood, M. D., Jones, S. E., Reader, M. R., & Saunders, N. R. (1989) · Comparative Biochemistry and Physiology Part B Comparative Biochemistry · doi:10.1016/0305-0491(89)90133-8 · Cited by 27 · see citing works
Jacobsen, M., Møllgård, K., Reynolds, M. L., & Saunders, N. R. (1983) · Developmental Brain Research · doi:10.1016/0165-3806(83)90159-1 · Cited by 27 · see citing works
Xvii.—The Effects of Fixatives and Other Reagents on Cell‐Size and Tissue‐Bulk
Tarkhan, A. A. (1931) · Journal of the Royal Microscopical Society · doi:10.1111/j.1365-2818.1931.tb01846.x · Cited by 26 · see citing works
Jacobsen, M., CLAUSEN, P. P., Jacobsen, G. K., Saunders, N. R., & Møllgård, K. (1982) · Developmental Brain Research · doi:10.1016/0165-3806(82)90024-4 · Cited by 23 · see citing works
Donaldson, H. H. (1894) · Journal of Morphology · doi:10.1002/jmor.1050090105 · Cited by 23 · see citing works
Proliferative zones in the epithelium of the choroid plexuses of the human embryo brain
Korzhevsky, D. E. (2000) · Neuroscience and Behavioral Physiology · doi:10.1007/bf02462607 · Cited by 12 · see citing works
QUANTITATIVE DEVELOPMENT of CHOROID PLEXUSES IN CHICK EMBRYO CEREBRAL VENTRICLES
Šťastný, F., & Rychter, Z. (1976) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1976.tb04346.x · Cited by 12 · see citing works
Development and plasticity of the retina in the opossum Monodelphis domestica
Djavadian, R. L., Bisti, S., Maccarone, R., Bartkowska, K., & Turlejski, A. (2006) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2006-1605 · Cited by 6 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Møllgård K Rostgaard J Ussing HH, Bindslev O, Sten-Knudsen O The transcellular compartment of tubulo-cisternal endoplasmic reticulum, a common feature of transporting epithelial cells Alfred Benzon Symposium 15; Copenhagen 1981
Cited by
Sorted by citations
Development and functions of the choroid plexus–cerebrospinal fluid system
Lun, M. P., Monuki, E. S., & Lehtinen, M. K. (2015) · Nature reviews. Neuroscience · doi:10.1038/nrn3921 · Cited by 682 · see citing works
A cellular and spatial map of the choroid plexus across brain ventricles and ages
Dani, N., Herbst, R. H., McCabe, C., Green, G. S., Kaiser, K., Head, J. P., Cui, J., Shipley, F. B., Jang, A., Dionne, D., et al. (2021) · Cell · doi:10.1016/j.cell.2021.04.003 · Cited by 388 · see citing works
Development of the choroid plexus and blood-CSF barrier
Liddelow, S. A. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00032 · Cited by 238 · see citing works
Emergence and Developmental Roles of the Cerebrospinal Fluid System
Fame, R. M., & Lehtinen, M. K. (2020) · Developmental Cell · doi:10.1016/j.devcel.2020.01.027 · Cited by 201 · see citing works
The choroid plexus: a missing link in our understanding of brain development and function
Saunders, N. R., Dzięgielewska, K. M., Fame, R. M., Lehtinen, M. K., & Liddelow, S. A. (2022) · Physiological Reviews · doi:10.1152/physrev.00060.2021 · Cited by 141 · see citing works
Alisch, J. S. R., Kiely, M., Triebswetter, C., Alsameen, M. H., Gong, Z., Khattar, N., Egan, J. M., & Bouhrara, M. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.734992 · Cited by 111 · see citing works
The choroid plexuses and their impact on developmental neurogenesis
Johansson, P. A. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00340 · Cited by 81 · see citing works
Liddelow, S. A., Dzięgielewska, K. M., Ek, C. J., Habgood, M. D., Bauer, H., Bauer, H., Lindsay, H. A., Wakefield, M. J., Strazielle, N., Kratzer, I., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065629 · Cited by 78 · see citing works
The molecular anatomy and functions of the choroid plexus in healthy and diseased brain
Kratzer, I., Ek, C. J., & Stolp, H. B. (2020) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2020.183430 · Cited by 67 · see citing works
Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate
Parichha, A., Suresh, V., Chatterjee, M., Kshirsagar, A., Ben‐Reuven, L., Olender, T., Taketo, M. M., Radošević, V., Bobić‐Rasonja, M., Trnski, S., et al. (2022) · Nature Communications · doi:10.1038/s41467-021-27602-z · Cited by 62 · see citing works
Receptor-mediated drug delivery of bispecific therapeutic antibodies through the blood-brain barrier
Pardridge, W. M. (2023) · Frontiers in Drug Delivery · doi:10.3389/fddev.2023.1227816 · Cited by 62 · see citing works
Campos, Y., Qiu, X., Gomero, E. M., Wakefield, R., HORNER, L. H., Brutkowski, W., Han, Y.-G., Solecki, D. J., Frase, S., Bongiovanni, A., et al. (2016) · Nature Communications · doi:10.1038/ncomms11876 · Cited by 55 · see citing works
Choroid plexus in developmental and evolutionary perspective
Bill, B., & Korzh, V. P. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00363 · Cited by 52 · see citing works
Functional and genetic analysis of choroid plexus development in zebrafish
Henson, H. E., Parupalli, C., Ju, B., & Taylor, M. R. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00364 · Cited by 44 · see citing works
Pardridge, W. M. (2021) · Pharmaceuticals · doi:10.3390/ph15010003 · Cited by 46 · see citing works
Liddelow, S. A., Dzięgielewska, K. M., Møllgård, K., Whish, S. C., Noor, N. M., Wheaton, B. J., Gehwolf, R., Wagner, A., Traweger, A., Bauer, H., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106592 · Cited by 43 · see citing works
Haddad, M. R., Donsante, A., Zerfas, P. M., & Kaler, S. G. (2013) · Molecular Therapy — Nucleic Acids · doi:10.1038/mtna.2013.27 · Cited by 40 · see citing works
A Conserved Developmental Mechanism Builds Complex Visual Systems in Insects and Vertebrates
Joly, J., Recher, G., Brombin, A., Ngo, K., & Hartenstein, V. (2016) · Current Biology · doi:10.1016/j.cub.2016.08.017 · Cited by 37 · see citing works
Choroid plexus aging: structural and vascular insights from the HCP-aging dataset
Sun, Z., Li, C., Zhang, J., Wısnıewskı, T., & Ge, Y. (2024) · Fluids and Barriers of the CNS · doi:10.1186/s12987-024-00603-y · Cited by 37 · see citing works
Pardridge, W. M. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114234 · Cited by 37 · see citing works
Pardridge, W. M., & Chou, T. (2021) · Pharmaceuticals · doi:10.3390/ph14060535 · Cited by 35 · see citing works
Moore, S. A., & Iulianella, A. (2021) · Open Biology · doi:10.1098/rsob.210042 · Cited by 35 · see citing works
Mutations in SMARCB1 and in other Coffin–Siris syndrome genes lead to various brain midline defects
Filatova, A., Rey, L. K., Lechler, M. B., Schaper, J., Hempel, M., Posmyk, R., Szczałuba, K., Santen, G. W. E., Wieczorek, D., & Nuber, U. A. (2019) · Nature Communications · doi:10.1038/s41467-019-10849-y · Cited by 31 · see citing works
MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus
Kaiser, K., Jang, A., Kompaníková, P., Lun, M. P., Procházka, J., Machoň, O., Dani, N., Procházková, M., Laurent, B., Gyllborg, D., et al. (2021) · Development · doi:10.1242/dev.192054 · Cited by 29 · see citing works
Brain development and bioenergetic changes
Rajan, A., & Fame, R. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106550 · Cited by 21 · see citing works
WNT5a Regulates Epithelial Morphogenesis in the Developing Choroid Plexus
Langford, M. B., O’Leary, C. J., Veeraval, L., White, A., Lanoue, V., & Cooper, H. M. (2019) · Cerebral Cortex · doi:10.1093/cercor/bhz330 · Cited by 23 · see citing works
Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage
Ho, K. H., Candat, A., Scarpetta, V., Faucourt, M., Weill, S., Salio, C., D’Este, E., Meschkat, M., Wurm, C. A., Kneussel, M., et al. (2023) · Developmental Cell · doi:10.1016/j.devcel.2023.10.003 · Cited by 24 · see citing works
Liddelow, S. A., Dzięgielewska, K. M., Møllgård, K., Phoenix, T. N., Temple, S., VandeBerg, J. L., & Saunders, N. R. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07821.x · Cited by 17 · see citing works
Transmigration of Trypanosoma brucei across an in vitro blood-cerebrospinal fluid barrier
Speidel, A., Theile, M., Pfeiffer, L., Herrmann, A., Figarella, K., Ishikawa, H., Schwerk, C., Schroten, H., Duszenko, M., & Mogk, S. (2022) · iScience · doi:10.1016/j.isci.2022.104014 · Cited by 13 · see citing works
Development of the brain ventricular system from a comparative perspective
Korzh, V. P. (2022) · Clinical Anatomy · doi:10.1002/ca.23994 · Cited by 11 · see citing works
Pathophysiology of the choroid plexus in brain diseases
Mihaljević, S., Michalicová, A., Bhide, M., & Kováč, A. (2021) · General Physiology and Biophysics · doi:10.4149/gpb_2021032 · Cited by 9 · see citing works
PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation
He, L., Wen, J., & Dai, Q. (2025) · eLife · doi:10.7554/elife.104076.3 · Cited by 2 · see citing works
Introduction to the Ventricular System and Choroid Plexus
Fujii, T., Youssefzadeh, J., Novel, M., & Neman, J. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801740-1.00001-9 · Cited by 3 · see citing works
PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferationPreprint
He, L., Wen, J., & Dai, Q. (2025) · eLife · doi:10.7554/elife.104076 · Cited by 3 · see citing works
Lacey, T. E., Fame, R. M., & Lehtinen, A. M. K. (2023) · Wiley eBooks · doi:10.1002/9781119860914.ch32 · Cited by 1 · see citing works
Choi, E.-Y., Wolfe, J. H. N., & Kaler, S. G. (2025) · Human Molecular Genetics · doi:10.1093/hmg/ddae201 · Cited by 1 · see citing works
Altered epithelial development of the lateral ventricle choroid plexus in Mllt11 mutants
Moore, S., Stanton‐Turcotte, D., Witt, E. A., & Iulianella, A. (2025) · Biology Open · doi:10.1242/bio.061966 · Cited by 1 · see citing works
Development of the Cerebrospinal Fluid Pathways during Embryonic and Fetal Life in Humans
Catala, M. (2018) · Springer eBooks · doi:10.1007/978-3-319-31889-9_2-2 · Cited by 1 · see citing works
Development of the Cerebrospinal Fluid Pathways during Embryonic and Fetal Life in Humans
Catala, M. (2018) · Springer eBooks · doi:10.1007/978-3-319-31889-9_2-1 · Cited by 1 · see citing works
Functional and Genetic Analysis of Choroid Plexus Development in Zebrafish
Henson, H. E. (2014) · doi:10.21007/etd.cghs.2014.0134 · Cited by 1 · see citing works
Fernandes, M. T., Li, L., Correia, E., Vieira, A., Afonso, D. A., Álvarez‐López, A. I., Campos, J., Mahmud, N., Meijer, M., Agirre, E., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.25.671514 · Cited by 1 · see citing works
Haddad, M. R., Donsante, A., Zerfas, P. M., & Kaler, S. G. (2013)
Pavlov, A. V., Анатольевна, Ф. О., & Кораблева, Т. В. (2020) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-020-00946-7
Development of the Cerebrospinal Fluid Pathways During Embryonic and Fetal Life in Humans
Catala, M. (2019) · Springer eBooks · doi:10.1007/978-3-319-27250-4_2 · Cited by 4 · see citing works
Development of the ventricles, choroid plexus and CSF outflow system
Korzh, V. P. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-819509-3.00009-2
PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferationPreprint
He, L., Wen, J., & Dai, Q. (2025) · eLife · doi:10.7554/elife.104076.1
Pro-neurogenic potential of blood cells cultured in autologous plasmaPreprint
Arora, R., Bhardwaj, A., Panda, N. K., Das, R., Sinharay, S., Patkulkar, P., Gupta, T., Bakshi, J. B., Virk, R. S., Nayak, G., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.19.643269 · Cited by 1 · see citing works
Emerging Human Choroid Plexus Organoid Models for Blood-CSF Barrier Research
Qiao, H., & Zhao, Z. (2025) · Neuromethods · doi:10.1007/978-1-0716-4474-4_4
PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferationPreprint
He, L., Wen, J., & Dai, Q. (2025) · eLife · doi:10.7554/elife.104076.2
Apsley, E. J., Tang, S. S., Vitiello, E., Imaz-Rosshandler, I., Fernández-Otero, M., Sapidou, K., Burnap, S. A., Struwe, W. B., Pjanic, M., Fullard, J. F., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.12.758506
- Authors
- Liddelow, S. A., Dziegielewska, K. M., VandeBerg, J. L., & Saunders, N. R.
- Affiliations
- The University of Melbourne (AU)
- Texas Biomedical Research Institute (US)
- Corresponding author
- Liddelow, Shane A
- Venue
- Cerebrospinal Fluid Research
- Published
- 2010-10-05
- Volume
- 7
- Issue
- 1
- Pages
- 16-16
- ISSN
- 1743-8454 (ISSN-L)
- PMC
- PMC2964622
- OpenAlex
- W2024706272
- Cited by
- 50
- References
- 51
- Citations by year
- 2026: 1 · 2025: 9 · 2024: 2 · 2023: 3 · 2022: 6 · 2021: 7 · 2020: 3 · 2019: 3 · 2018: 2 · 2016: 2 · 2015: 3 · 2014: 5 · 2013: 3
- FWCI
- 0.52
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Cerebrospinal Fluid Research (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation
- Medical Research Council
- National Health and Medical Research Council
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Cerebrospinal fluid and hydrocephalus
- Life Sciences › Neuroscience › Neurology › Barrier Structure and Function Studies
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- choroid plexus development, lateral ventricle, choroid plexus epithelial cells, Monodelphis domestica, marsupials, cell proliferation, blood-CSF barrier, BrdU labeling, cell migration, postnatal development
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
