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The biodiversity hypothesis and allergic disease: world allergy organization position statement
Open accessAbstract
Biodiversity loss and climate change secondary to human activities are now being associated with various adverse health effects. However, less attention is being paid to the effects of biodiversity loss on environmental and commensal (indigenous) microbiotas. Metagenomic and other studies of healthy and diseased individuals reveal that reduced biodiversity and alterations in the composition of the gut and skin microbiota are associated with various inflammatory conditions, including asthma, allergic and inflammatory bowel diseases (IBD), type1 diabetes, and obesity. Altered indigenous microbiota and the general microbial deprivation characterizing the lifestyle of urban people in affluent countries appear to be risk factors for immune dysregulation and impaired tolerance. The risk is further enhanced by physical inactivity and a western diet poor in fresh fruit and vegetables, which may act in synergy with dysbiosis of the gut flora. Studies of immigrants moving from non-affluent to affluent regions indicate that tolerance mechanisms can rapidly become impaired in microbe-poor environments. The data on microbial deprivation and immune dysfunction as they relate to biodiversity loss are evaluated in this Statement of World Allergy Organization (WAO). We propose that biodiversity, the variability among living organisms from all sources are closely related, at both the macro- and micro-levels. Loss of the macrodiversity is associated with shrinking of the microdiversity, which is associated with alterations of the indigenous microbiota. Data on behavioural means to induce tolerance are outlined and a proposal made for a Global Allergy Plan to prevent and reduce the global allergy burden for affected individuals and the societies in which they live.
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![Figure 1 Two global megatrends in biodiversity and public health. (a) Declining biodiversity (percentage change) since 1970 as measured by two indices. WPSI=Waterbird Population Status Index; LPI=Living Planet Index [14]. (b) Increasing trends in the prevalence of inflammatory civilization diseases, asthma and allergic rhinitis among military conscripts in 1966-2003 [165] as an example (modified from ref. [14]).](/paper-figures/efdc9d3a359f4291b672a407ffa3d7a9/the-biodiversity-hypothesis-and-allergic-disease-world-allergy-organization-figure-1.jpg)
![Figure 2 Trends in a) prevalence of asthma and allergic rhinitis [165], b) incidence of pediatric inflammatory bowel disease [59], c) incidence of colon and rectum cancer [168], and d) prevalence of coeliac disease and type 1 diabetes [166], e) incidence of Wegener’s granulomatosis [167], and f) incidence of non-Hodgkin’s lymphoma in Finland in 1950-2009 [168].](/paper-figures/2b9e9b7c54214fdf9ab2a41ab19193fd/the-biodiversity-hypothesis-and-allergic-disease-world-allergy-organization-figure-2.jpg)
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“Similarly, the biodiversity hypothesis highlights the role of natural environments in shaping the human microbiome [38], enhancing immune balance, and reducing inflammation-related diseases [38,39,40].”
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Cites
An obesity-associated gut microbiome with increased capacity for energy harvest
Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444
A human gut microbial gene catalogue established by metagenomic sequencing
MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624
Pattern Recognition Receptors and Inflammation
Takeuchi, O., & Akira, S. (2010) · Cell · doi:10.1016/j.cell.2010.01.022 · Cited by 8,895
Diversity of the Human Intestinal Microbial Flora
Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913
A core gut microbiome in obese and lean twins
Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., Sogin, M. L., Jones, W. J., Roe, B. A., Affourtit, J. P., et al. (2009) · Nature · doi:10.1038/nature07540 · Cited by 7,823
Linking long-term dietary patterns with gut microbial enterotypes
Wu, G. D., Chen, J., Hoffmann, C., Bittinger, K., Chen, Y.-Y., Keilbaugh, S. A., Bewtra, M., Knights, D., Walters, W. A., Knight, R., et al. (2011) · Science · doi:10.1126/science.1208344 · Cited by 6,513
De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., Collini, S., Pieraccini, G., & Lionetti, P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005963107 · Cited by 5,579
Hay fever, hygiene, and household size.
Strachan, D. P. (1989) · BMJ · doi:10.1136/bmj.299.6710.1259 · Cited by 5,054
The gut microbiota shapes intestinal immune responses during health and disease
Round, J. L., & Mazmanian, S. K. (2009) · Nature Reviews Immunology · doi:10.1038/nri2515 · Cited by 5,029
Global Biodiversity: Indicators of Recent Declines
Butchart, S. H. M., Walpole, M., Collen, B., van Strien, A., Scharlemann, J. P. W., Almond, R. E. A., Baillie, J. E. M., Bomhard, B., Brown, C., Bruno, J., et al. (2010) · Science · doi:10.1126/science.1187512 · Cited by 4,892
Cited by
Sorted by citations
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Wang, M., Li, H., Zhang, W., Zhang, L., Wang, S., Miao, J., Jia, L., Zhang, Y., Gao, H., Zhang, X., et al. (2025) · PLoS ONE · doi:10.1371/journal.pone.0311207 · Cited by 14
Primary Prevention of Allergic Diseases: The Role of Early Exposure to Cow's Milk Formula
Mastrorilli, C., Santoro, A., & Caffarelli, C. (2020) · Frontiers in Pediatrics · doi:10.3389/fped.2020.00420 · Cited by 14
Stojkovic-Andjelkovic, A., Simovic, A. M., Bogdanović, Z., Banković, D., & Poskurica, M. (2016) · Srpski arhiv za celokupno lekarstvo · doi:10.2298/sarh1602038s · Cited by 14
Mazhary, Z., Fard, N. A., Minuchehr, Z., & Javanshir, N. (2019) · Informatics in Medicine Unlocked · doi:10.1016/j.imu.2019.100280 · Cited by 14
Allergy as a sentinel measure of planetary health and biodiversity loss
Prescott, S. L. (2020) · Allergy · doi:10.1111/all.14255 · Cited by 14
Li, P., Ma, X., Liu, D., Wei, Y., Li, P., Hou, H., Yao, J., Chen, A., Liang, Y., Zhou, Z., et al. (2022) · Environmental Pollution · doi:10.1016/j.envpol.2022.120415 · Cited by 14
Armari, M., Zavattaro, E., Trejo, C. F., Galeazzi, A., Grossetti, A., Veronese, F., Savoia, P., & Azzimonti, B. (2024) · Antibiotics · doi:10.3390/antibiotics13080697 · Cited by 13
Mazur, A., Szylling, A., Bielecka, T., Strzelak, A., & Kulus, M. (2017) · Journal of Asthma · doi:10.1080/02770903.2017.1400046 · Cited by 13
Asthma in adolescents – Prevalence trends and associated factors in northeast Brazil
Oliveira-Santos, S., Franco, J. M., Barreto, Í. D. D. C., Solé, D., & Gurgel, R. Q. (2014) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2014.05.006 · Cited by 14
H omo sapiens , industrialisation and the environmental mismatch hypothesis
Longman, D. P., & Shaw, C. N. (2025) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.70094 · Cited by 23
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Ke, H., Yao, H., & Wei, P. (2025) · Current Research in Microbial Sciences · doi:10.1016/j.crmicr.2025.100362 · Cited by 16
The Microbiome as a Gateway to Prevention of Allergic Disease Development
Kloepfer, K. M., McCauley, K. E., & Kirjavainen, P. V. (2022) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2022.05.033 · Cited by 14
Migrants and allergy: a new view of the atopic march
Biagioni, B., Vitiello, G., Bormioli, S., Tarrini, D., Lombardi, C., Rossi, O., & Parronchi, P. (2019) · European Annals of Allergy and Clinical Immunology · doi:10.23822/eurannaci.1764-1489.96 · Cited by 12
Prescott, S. L., & Bland, J. S. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17041407 · Cited by 12
Allergy-Related Disorders in the Construction Industry
Carino, M., Romita, P., & Foti, C. (2013) · ISRN Preventive Medicine · doi:10.5402/2013/864679 · Cited by 12
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Pacheco-Torgal, F. (2014) · Springer eBooks · doi:10.1007/978-3-319-09287-4_1 · Cited by 11
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Kielenniva, K., Ainonen, S., Vänni, P., Paalanne, N., Renko, M., Salo, J., Tejesvi, M. V., Pokka, T. M.-L., Pirttilä, A. M., & Tapiainen, T. (2022) · Clinical & Experimental Allergy · doi:10.1111/cea.14117 · Cited by 9
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Laha, A., Moitra, S., & Podder, S. (2023) · Clinical & Experimental Allergy · doi:10.1111/cea.14266 · Cited by 10
Use of probiotics to prevent ventilator-associated pneumonia: A survey of pharmacists' attitudes
Wheeler, K. E., Cook, D. J., Mehta, S., Calce, A., Guenette, M. D., Perreault, M. M., Thiboutot, Z., Duffett, M., & Burry, L. D. (2015) · Journal of Critical Care · doi:10.1016/j.jcrc.2015.10.016 · Cited by 10
Yao, J., & Sbihi, H. (2016) · Canadian Journal of Public Health · doi:10.17269/cjph.107.5614 · Cited by 10
How do Microbiota Influence the Development and Natural History of Eczema and Food Allergy?
Marrs, T., & Flohr, C. (2016) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000001314 · Cited by 10
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von Hertzen, L. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114515003979 · Cited by 10
Galitskaya, P., Luukkonen, A., Roslund, M. I., Mänttäri, M., Yli-Viikari, A., Tyrväinen, L., Sinkkonen, A., & Laitinen, O. H. (2024) · BMC Public Health · doi:10.1186/s12889-024-20655-x · Cited by 10
Greenspace Morphology and Preterm Birth: A State-Wide Study in Georgia, United States (2001–2016)
Wang, H., Huang, X., Hao, H., & Chang, H. H. (2024) · Environmental Health Perspectives · doi:10.1289/ehp14571 · Cited by 9
Xu, S., Marcon, A., Bertelsen, R. J., Benediktsdóttir, B., Brandt, J. G., Frohn, L. M., Geels, C., Gíslason, Þ., Heinrich, J., Holm, M., et al. (2025) · Environmental Research · doi:10.1016/j.envres.2025.120938 · Cited by 9
Milani, T., Sandy, C. M., Calazans, A. P. C. T., Silva, R. Q., da Fonseca, V. M. B., Martins, F. S., & Borges, M. D. C. (2022) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-022-10014-w · Cited by 9
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Antó, J. M., Pearce, N. E., Douwes, J. E., García‐Aymerich, J., Pembrey, L., Richiardi, L., & Sunyer, J. (2023) · International Journal of Epidemiology · doi:10.1093/ije/dyad035 · Cited by 10
Poutiainen, H., Hakulinen, T., Mäki, P., & Laatikainen, T. K. (2016) · International Journal of Nursing Practice · doi:10.1111/ijn.12478 · Cited by 9
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Hall, K. S., Barnes, C. R., Duggan, L., Walton, S., Moran, P., Turner, K. M., & Evans, J. (2024) · Wellbeing Space and Society · doi:10.1016/j.wss.2024.100187 · Cited by 10
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Martín‐Masot, R., Díaz, J. J., Santamaria-Orleans, A., & Navas‐López, V. M. (2023) · Nutrients · doi:10.3390/nu15163586 · Cited by 8
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Karmakar, B., Saha, B., Jana, K., & Gupta-Bhattacharya, S. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra120.015801 · Cited by 8
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Daschner, Á., González‐Fernández, J., Valls, A., Frutos, C. D., Rodero, M., & Cuéllar, C. (2015) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2015.01.009 · Cited by 8
Leru, P. M., Matei, D. B., & Ianovici, N. (2015) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 8
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Palacios-Garcia, I., & Parada, F. J. (2021) · doi:10.31234/osf.io/thuvc · Cited by 21
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Zhang, L., Xu, W., Meng, H. Y. H., Ching, J. Y. L., Liu, Y., Wang, S., Yan, S., Lin, L., Cheong, P. K., Ip, K. L., et al. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2443117 · Cited by 7
Ran, H., Xiao, H., Zhou, X., Guo, L., & Lu, S. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.9232 · Cited by 9
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Parker, W., Patel, E. M., Jirků‐Pomajbíková, K., & Laman, J. D. (2023) · iScience · doi:10.1016/j.isci.2023.106167 · Cited by 6
Li, X., Luo, J., Nie, C., Li, Q., Sun, X., Li, H., & Zhang, Y. (2020) · Allergy Asthma and Clinical Immunology · doi:10.1186/s13223-020-00475-5 · Cited by 6
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Demain, J. G. (2020) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0000000000000660 · Cited by 6
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Bœuf, G. (2014) · Collège de France eBooks · doi:10.4000/books.cdf.3610 · Cited by 10
Assmuth, T. W., Dubrovin, T., & Lyytimäki, J. M. (2019) · Environment Systems & Decisions · doi:10.1007/s10669-019-09751-1 · Cited by 6
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Grau, M., Pedro Mardones, P., Donoso, G., Aguilera, R., Loreto Nicklas, D., Iglesias, V., & Cãrdova, A. (2018) · Revista médica de Chile · doi:10.4067/s0034-98872018000900994 · Cited by 5
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Conte, M., Varraso, R., Fournier, A., Rothwell, J. A., Baglietto, L., Fornili, M., Sbidian, É., & Severi, G. (2023) · Environmental Research · doi:10.1016/j.envres.2023.117062 · Cited by 3
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Self-citationParada, F. J., & Palacios-García, I. (2022) · Adaptive Behavior · doi:10.1177/10597123221088874 · Cited by 3
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Metadata
- Authors
- Haahtela, T., Holgate, S., Pawankar, R., Akdis, C. A., Benjaponpitak, S., Caraballo, L., Demain, J., Portnoy, J., & von Hertzen, L.
- Affiliations
- Helsinki University Hospital (FI)
- University of Southampton (GB)
- Nippon Medical School (JP)
- Mahidol University (TH)
- Universidad de Cartagena (CO)
- University of Washington (US)
- University of Missouri–Kansas City (US)
- Corresponding author
- Haahtela, Tari
- ORCID
- Venue
- World Allergy Organization Journal
- Publisher
- Elsevier BV
- Published
- 2013
- Volume
- 6
- Issue
- 1
- Pages
- 3
- ISSN
- 1939-4551 (ISSN-L)
- PMC
- PMC3646540
- OpenAlex
- W2105617257
- Cited by
- 426
- References
- 168
- Citations by year
- 2026: 30 · 2025: 24 · 2024: 39 · 2023: 37 · 2022: 36 · 2021: 40 · 2020: 38 · 2019: 33 · 2018: 30 · 2017: 29 · 2016: 27 · 2015: 31 · 2014: 23 · 2013: 7
- FWCI
- 13.15
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- World Allergy Organization Journal (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Työväentutkimus Vuosikirja (submittedVersion)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion, cc-by)
- Zurich Open Repository and Archive (University of Zurich)
- Funders
- National Institute for Health and Care Research (NF-SI-0510-10021)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Keywords
- biodiversity loss, allergic diseases, gut microbiota, skin microbiome, dysbiosis, immune tolerance, immune dysregulation, asthma, inflammatory bowel disease, type 1 diabetes, obesity, climate change, urban lifestyle, immigrant health, allergy prevention
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