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Cited by 677

The DOI matches its Crossref record; 104 of the 104 references it cites were found in a registry or an index.

Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression

Open access
DeNardo, David G, Coussens, Lisa M·2007·Breast Cancer Research

Abstract

Recent insights into the molecular and cellular mechanisms underlying cancer development have revealed that immune cells functionally regulate epithelial cancer development and progression. Moreover, accumulated clinical and experimental data indicate that the outcome of an immune response toward an evolving breast neoplasm is largely determined by the type of immune response elicited. Acute tumor-directed immune responses involving cytolytic T lymphocytes appear to protect against tumor development, whereas immune responses involving chronic activation of humoral immunity, infiltration by Th2 cells, and protumor-polarized innate inflammatory cells result in the promotion of tumor development and disease progression. Herein we review this body of literature and summarize important new findings revealing the paradoxical role of innate and adaptive leukocytes as regulators of breast carcinogenesis.

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Crossref · 10.1186/bcr1746

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Metadata

Authors
DeNardo, D. G., & Coussens, L. M.
Venue
Breast Cancer Research
Published
2007-08
Volume
9
Issue
4
Pages
212-212
ISSN
  • 1465-5411 (ISSN-L)
  • 1465-542X
OpenAlex
W2031576122
Cited by
677
References
104
FWCI
7.24
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. https://app.cochat.ai/papers/10.1186/bcr1746
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DeNardo, D. G., & Coussens, L. M. (2007). Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Research. https://doi.org/10.1186/bcr1746

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.