Cited by 187Antibiotic Use and ResistanceAntibiotics Pharmacokinetics and EfficacySepsis Diagnosis and Treatment

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Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis

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Havey, Thomas C, Fowler, Robert A, Daneman, Nick·2011·Critical Care

DOI 10.1186/cc10545PMC PMC3388653

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Abstract

Introduction: The optimal duration of antibiotic therapy for bloodstream infections is unknown. Shorter durations of therapy have been demonstrated to be as effective as longer durations for many common infections; similar findings in bacteremia could enable hospitals to reduce antibiotic utilization, adverse events, resistance and costs. Methods: A search of the MEDLINE, EMBASE and COCHRANE databases was conducted for the years 1947-2010. Controlled trials were identified that randomized patients to shorter versus longer durations of treatment for bacteremia, or the infectious foci most commonly causing bacteremia in critically ill patients (catheter-related bloodstream infections (CRBSI), intra-abdominal infections, pneumonia, pyelonephritis and skin and soft-tissue infections (SSTI)). Results: Twenty-four eligible trials were identified, including one trial focusing exclusively on bacteremia, zero in catheter related bloodstream infection, three in intra-abdominal infection, six in pyelonephritis, thirteen in pneumonia and one in skin and soft tissue infection. Thirteen studies reported on 227 patients with bacteremia allocated to 'shorter' or 'longer' durations of treatment. Outcome data were available for 155 bacteremic patients: neonatal bacteremia ( n = 66); intra-abdominal infection (40); pyelonephritis (9); and pneumonia (40). Among bacteremic patients receiving shorter (5-7 days) versus longer (7-21 days) antibiotic therapy, no significant difference was detected with respect to rates of clinical cure (45/52 versus 47/49, risk ratio 0.88, 95% confidence interval [CI] 0.77-1.01), microbiologic cure (28/28 versus 30/32, risk ratio 1.05, 95% CI 0.91-1.21), and survival (15/17 versus 26/29, risk ratio 0.97, 95% CI 0.76-1.23). Conclusions: No significant differences in clinical cure, microbiologic cure and survival were detected among bacteremic patients receiving shorter versus longer duration antibiotic therapy. An adequately powered randomized trial of bacteremic patients is needed to confirm these findings.

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Figure 1 Flowchart describing citations screened, studies included for searches of bacteremia, and infectious syndromes most commonly causing bacteremia. CRBSI, catheter-related bloodstream infection; SSTI, skin and soft tissue infection.CC BY · PubMed Central

Figure 2 Forest plot for outcome of clinical cure among bacteremic subgroups of randomized trials of shorter versus longer antibiotic treatment. CI, confidence interval; df, degrees of freedom; M-H, Mantel-Haenszel.CC BY · PubMed Central

Figure 3 Forest plot for outcome of microbiologic cure among bacteremic subgroups of randomized trials of shorter versus longer antibiotic treatment. CI, confidence interval; df, degrees of freedom; M-H, Mantel-Haenszel.CC BY · PubMed Central

Figure 4 Forest plot for outcome of survival among bacteremic subgroups of randomized trials of shorter versus longer antibiotic treatment. CI, confidence interval; df, degrees of freedom; M-H, Mantel-Haenszel.CC BY · PubMed Central

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Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults
Mandell, L. A., Wunderink, R. G., Anzueto, A., Bartlett, J. G., Campbell, G. D., Dean, N. C., Dowell, S. F., File, T. M., Musher, D. M., Niederman, M. S., et al. (2007) · Clinical Infectious Diseases · doi:10.1086/511159 · Cited by 6,182
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
Kumar, A., Roberts, D., Wood, K. E., Light, B., Parrillo, J. E., Sharma, S., Suppes, R., Feinstein, D., Zanotti, S., Taiberg, L., et al. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000217961.75225.e9 · Cited by 6,109
Guidelines for the Management of Adults with Hospital-acquired, Ventilator-associated, and Healthcare-associated Pneumonia
(2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200405-644st · Cited by 5,932
Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children
Liu, C., Bayer, A. S., Cosgrove, S. E., Daum, R. S., Fridkin, S. K., Gorwitz, R. J., Kaplan, S. L., Karchmer, A. W., Levine, D. P., Murray, B. E., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/ciq146 · Cited by 4,260
International Study of the Prevalence and Outcomes of Infection in Intensive Care Units
Vincent, J. (2009) · JAMA · doi:10.1001/jama.2009.1754 · Cited by 3,639
Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America.
Mermel, L. A., Allon, M., Bouza, E., Craven, D. E., Flynn, P., O'Grady, N. P., Raad, I. I., Rijnders, B. J. A., Sherertz, R. J., & Warren, D. K. (2009) · Clinical Infectious Diseases · doi:10.1086/599376 · Cited by 3,638
International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases
Gupta, K., Hooton, T. M., Naber, K. G., Wullt, B., Colgan, R., Miller, L. G., Moran, G. J., Nicolle, L. E., Raz, R., Schaeffer, A. J., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/ciq257 · Cited by 3,038
The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting
Ibrahim, E. H., Sherman, G., Ward, S., Fraser, V. J., & Kollef, M. H. (2000) · Chest · doi:10.1378/chest.118.1.146 · Cited by 1,779
Practice Guidelines for the Diagnosis and Management of Skin and Soft-Tissue Infections
Stevens, D. L., Bisno, A. L., Chambers, H. F. “., Everett, E. D., Dellinger, P. E., Goldstein, E. J. C., Gorbach, S. L., Hirschmann, J. V., Kaplan, E. L., Montoya, J. G., et al. (2005) · Clinical Infectious Diseases · doi:10.1086/497143 · Cited by 1,613
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Liu, C., Bayer, A., Cosgrove, S. E., Daum, R. S., Fridkin, S. K., Gorwitz, R. J., Kaplan, S. L., Karchmer, A. W., Levine, D. P., Murray, B. E., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir034 · Cited by 1,599
Diagnosis and Management of Complicated Intra-abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of America
Solomkin, J. S., Mazuski, J. E., Bradley, J. S., Rodvold, K. A., Goldstein, E. J. C., Baron, E. J., O’Neill, P. J., Chow, A. W., Dellinger, E. P., Eachempati, S. R., et al. (2009) · Clinical Infectious Diseases · doi:10.1086/649554 · Cited by 1,571
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Chastre, J., Wolff, M., Fagon, J.-Y., Chevret, S., Thomas, F., Wermert, D., Clementi, E., Gonzalez, J., Jusserand, D., Asfar, P., et al. (2003) · JAMA · doi:10.1001/jama.290.19.2588 · Cited by 1,376
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Weinstein, M. P., Towns, M., Quartey, S. M., Mirrett, S., Reimer, L. G., Parmigiani, G., & Reller, L. B. (1997) · Clinical Infectious Diseases · doi:10.1093/clind/24.4.584 · Cited by 1,225
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Hecker, M. T., Aron, D. C., Patel, N. P., Lehmann, M. K., & Donskey, C. J. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.8.972 · Cited by 495
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Berthoud, T. K., Hamill, M. M., Lillie, P. J., Hwenda, L., Collins, K. A., Ewer, K., Milicic, A., Poyntz, H., Lambe, T., Fletcher, H. A., et al. (2010) · Clinical Infectious Diseases · doi:10.1093/cid/ciq015 · Cited by 384
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el Moussaoui, R., de Borgie, C. A. J. M., van den Broek, P., Hustinx, W. N. M., Bresser, P., van den Berk, G. E. L., Poley, J., van den Berg, B., Krouwels, F. H., Bonten, M. J. M., et al. (2006) · BMJ · doi:10.1136/bmj.332.7554.1355 · Cited by 337
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Short-course versus long-course antibiotic treatment of spontaneous bacterial peritonitis
Runyon, B. A., McHutchison, J. G., Antillon, M. R., Akriviadis, E. A., & Montano, A. A. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)90677-d · Cited by 309
Outcomes of Primary and Catheter-related Bacteremia
Renaud, B., & Brun‐Buisson, C. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.7.9912080 · Cited by 304
Comparison of Short-Course (5 Days) and Standard (10 Days) Treatment for Uncomplicated Cellulitis
Hepburn, M. J., Dooley, D. P., Skidmore, P. J., Ellis, M. W., Starnes, W. F., & Hasewinkle, W. C. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.15.1669 · Cited by 240
Nosocomial Bacteremia in Critically Ill Patients: A Multicenter Study Evaluating Epidemiology and Prognosis
Vallés, J., Leon, C., & Spanish Collaborative Group for Infections in Intensive Care Units of Sociedad Espanola de Medicina Intensiva y Unidades Coronarias (SEMIUC) (1997) · Clinical Infectious Diseases · doi:10.1093/clinids/24.3.387 · Cited by 240
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Garrouste-Orgeas, M., Timsit, J., Tafflet, M., Misset, B., Zahar, J., Soufir, L., Lazard, T., Jamali, S., Mourvillier, B., Cohen, Y., et al. (2006) · Clinical Infectious Diseases · doi:10.1086/500318 · Cited by 205
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Three day versus five day treatment with amoxicillin for non-severe pneumonia in young children: a multicentre randomised controlled trial
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Self-citation
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Siegel, R. E., Alicea, M., Lee, A. M., & Blaiklock, R. G. (1999) · American Journal of Therapeutics · doi:10.1097/00045391-199907000-00007 · Cited by 55
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Hedrick, T. L., Evans, H. L., Smith, R. L., McElearney, S. T., Schulman, A. S., Chong, T. W., Pruett, T. L., & Sawyer, R. G. (2006) · Surgical Infections · doi:10.1089/sur.2006.7.419 · Cited by 53
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Short- versus long-course antibiotic therapy for acute pyelonephritis in adolescents and adults: A meta-analysis of randomized controlled trials
Kyriakidou, K. G., Rafailidis, P. I., Matthaiou, D. K., Athanasiou, S., & Falagas, M. E. (2008) · Clinical Therapeutics · doi:10.1016/j.clinthera.2008.10.007 · Cited by 49
Short antibiotic treatment courses or how short is short?
Rubinstein, E. (2007) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2007.06.017 · Cited by 47
Variability of treatment duration for bacteraemia in the critically ill: A multinational survey.
Corona, A. (2003) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkg447 · Cited by 43
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Hassen, M. F., Ayed, S., Ali, H. B. S., Gharbi, R., Marghli, S., & Elatrous, S. (2008) · Annales Françaises d Anesthésie et de Réanimation · doi:10.1016/j.annfar.2008.10.021 · Cited by 41
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Vuori‐Holopainen, E., Peltola, H., KALLIO, M. J. T., & for the SE-TU Study Group (2000) · European Journal of Pediatrics · doi:10.1007/pl00008360 · Cited by 41
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de Gier, R. P. E., Karperien, A., Bouter, K. P., Zwinkels, M. G. J., Verhoef, J., Knol, W., Boon, T. A., & Hoepelman, I. M. (1995) · International Journal of Antimicrobial Agents · doi:10.1016/0924-8579(95)00011-v · Cited by 33
Efficacité comparée de la ceftriaxone dans un traitement de dix jours versus un traitement raccourci de cinq jours des pneumonies aigues communautaires de l'adulte hospitalisé avec facteur de risque
Léophonte, P., Choutet, P., GAILLAT, J., PETITPRETZ, P., Portier, H., Montestruc, F., Pecking, M., & BELS, F. D. (2002) · Médecine et Maladies Infectieuses · doi:10.1016/s0399-077x(02)00384-0 · Cited by 29
Therapy of Symptomatic Pyelonephritis in Women
Gleckman, R. A., Bradley, P., Roth, R., Hibert, D., & Pelletier, C. (1985) · The Journal of Urology · doi:10.1016/s0022-5347(17)48870-7 · Cited by 28
How long should we treat community-acquired pneumonia?
Scalera, N. M., & File, T. M. (2007) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0b013e3280555072 · Cited by 25
Pneumonia in Term Neonates: Laboratory Studies and Duration of Antibiotic Therapy
Engle, W. D., Jackson, G. L., Sendelbach, D. M., Stehel, E. K., Ford, D., McHugh, K., Norris, M. R., Vedro, D. A., Velaphi, S., Michelow, I. C., et al. (2003) · Journal of Perinatology · doi:10.1038/sj.jp.7210949 · Cited by 19
THE LENGTH OF ANTIMICROBIAL THERAPY IN UPPER VS. LOWER URINARY TRACT INFECTION OF CHILDHOOD
Pylkkänen, J., VILSKA, J., & Koskimies, O. (1981) · Acta Paediatrica · doi:10.1111/j.1651-2227.1981.tb06245.x · Cited by 14
Short-course therapy for catheter-associated Staphylococcus aureus bacteremia
Ehni, W. F. (1989) · Archives of Internal Medicine · doi:10.1001/archinte.149.3.533 · Cited by 9
Short course of antibiotic treatment in spontaneous bacterial peritonitis: a randomized controlled study.
Chaudhry, Z. I., Nisar, S., Ahmed, U., & Ali, M. (2000) · Journal of College of Physicians And Surgeons Pakistan · Cited by 7
Comparison of Ciprofloxacin (7 Days) and Trimethoprim-Sulfamethoxazole (14 Days) for Acute Uncomplicated Pyelonephritis in Women: A Randomized Trial
Talan, D. A., Stamm, W. E., Hooton, T. M., Moran, G. J., Burke, T., Iravani, A., Reuning-Scherer, J., & Church, D. A. (2000) · JAMA · doi:10.1001/jama.283.12.1583

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Authors: Havey, T. C., Fowler, R. A., & Daneman, N.
Affiliations: University of Toronto (CA)
Sunnybrook Health Science Centre (CA)
Corresponding author: Daneman, Nick
ORCID: Fowler, Robert A
Daneman, Nick
Venue: Critical Care
Publisher: Springer Science and Business Media LLC
Published: 2011-11-15
Volume: 15
Issue: 6
Pages: R267-R267
ISSN: 1364-8535 (ISSN-L)
DOI: 10.1186/cc10545
PMC: PMC3388653
OpenAlex: W2146470820
Cited by: 187
References: 60
Citations by year: 2026: 3 · 2025: 11 · 2024: 6 · 2023: 16 · 2022: 12 · 2021: 21 · 2020: 19 · 2019: 14 · 2018: 19 · 2017: 19 · 2016: 11 · 2015: 20 · 2014: 7 · 2013: 5 · 2012: 4
FWCI: 0.59
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/2.0/ (tdm)
creativecommons.org/licenses/by/2.0/ (vor)
Locations: Critical Care (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
TSpace (University of Toronto) (submittedVersion)
Funders: Heart and Stroke Foundation of Canada
Ontario Ministry of Health and Long-Term Care
Canadian Institutes of Health Research
Topics: Health Sciences › Medicine › Infectious Diseases › Antibiotic Use and Resistance
Health Sciences › Medicine › Pharmacology (medical) › Antibiotics Pharmacokinetics and Efficacy
Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Sepsis Diagnosis and Treatment
Keywords: bacteremia, antibiotic duration, short-course antibiotic therapy, bloodstream infection, clinical cure, microbiologic cure, survival, catheter-related bloodstream infection, intra-abdominal infection, pyelonephritis, pneumonia, skin and soft tissue infections, neonatal bacteremia, antibiotic use
MeSH terms: Anti-Bacterial Agents, Humans, Pyelonephritis, Time Factors, Bacteremia, Pneumonia, Bacterial, Soft Tissue Infections, Catheter-Related Infections, Intraabdominal Infections

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Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis

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