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Cited by 278

The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.

Bench-to-bedside review: Delirium in ICU patients - importance of sleep deprivation

Open access
Weinhouse, Gerald L, Schwab, Richard J, Watson, Paula L, Patil, Namrata, Vaccaro, Bernardino, Pandharipande, Pratik, Ely, E Wesley·2009·Critical Care

Abstract

Delirium occurs frequently in critically ill patients and has been associated with both short-term and long-term consequences. Efforts to decrease delirium prevalence have been directed at identifying and modifying its risk factors. One potentially modifiable risk factor is sleep deprivation. Critically ill patients are known to experience poor sleep quality with severe sleep fragmentation and disruption of sleep architecture. Poor sleep while in the intensive care unit is one of the most common complaints of patients who survive critical illness. The relationship between delirium and sleep deprivation remains controversial. However, studies have demonstrated many similarities between the clinical and physiologic profiles of patients with delirium and sleep deprivation. This article aims to review the literature, the clinical and neurobiologic consequences of sleep deprivation, and the potential relationship between sleep deprivation and delirium in intensive care unit patients. Sleep deprivation may prove to be a modifiable risk factor for the development of delirium with important implications for the acute and long-term outcome of critically ill patients.

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Metadata

Authors
Weinhouse, G. L., Schwab, R. J., Watson, P. L., Patil, N., Vaccaro, B., Pandharipande, P., & Ely, E. W.
Venue
Critical Care
Published
2009
Volume
13
Issue
6
Pages
234
ISSN
1364-8535 (ISSN-L)
OpenAlex
W1985522328
Cited by
278
References
52
FWCI
6.36
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Bench-to-bedside review: Delirium in ICU patients - importance of sleep deprivation. https://app.cochat.ai/papers/10.1186/cc8131
The paper
Weinhouse, G. L., Schwab, R. J., Watson, P. L., Patil, N., Vaccaro, B., Pandharipande, P., & Ely, E. W. (2009). Bench-to-bedside review: Delirium in ICU patients - importance of sleep deprivation. Critical Care. https://doi.org/10.1186/cc8131

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.