The DOI matches its Crossref record; 208 of the 208 references it cites were found in a registry or an index.
Sepsis biomarkers: a review
Open accessAbstract
Introduction: Biomarkers can be useful for identifying or ruling out sepsis, identifying patients who may benefit from specific therapies or assessing the response to therapy. Methods: We used an electronic search of the PubMed database using the key words "sepsis" and "biomarker" to identify clinical and experimental studies which evaluated a biomarker in sepsis. Results: The search retrieved 3370 references covering 178 different biomarkers. Conclusions: Many biomarkers have been evaluated for use in sepsis. Most of the biomarkers had been tested clinically, primarily as prognostic markers in sepsis; relatively few have been used for diagnosis. None has sufficient specificity or sensitivity to be routinely employed in clinical practice. PCT and CRP have been most widely used, but even these have limited ability to distinguish sepsis from other inflammatory conditions or to predict outcome.
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Items 201–208 of 208
Terminal complement complex in septic shock with capillary leakage: marker of complement activation?
Schuerholz, T., Leuwer, M., Meyer, M. C., Vangerow, B., Kube, F., Kirschfink, M., & Marx, G. (2005) · European Journal of Anaesthesiology · doi:10.1017/s0265021505000931 · Cited by 10
McKindley, D. S., Chichester, C. O., & Raymond, R. M. (1999) · Shock · doi:10.1097/00024382-199912000-00009 · Cited by 9
Ebdrup, L., Krog, J., Granfeldt, A., Tønnesen, E., & Hokland, M. (2008) · Scandinavian Journal of Immunology · doi:10.1111/j.1365-3083.2008.02157.x · Cited by 9
Lipopolysaccharide decreasing albumin expression in rat hepatocytes.
Wang, X., Li, W., Lü, J., et al. (2005) · PubMed · Cited by 8
Endotoxemia enhances expression of the signaling receptor (GP130) on protein and molecular level
Marsik, C. L., Halama, T., Cardona, F., Kanter‐Schlifke, I., Mittermayer, F., & Jilma, B. (2005) · Clinical Immunology · doi:10.1016/j.clim.2004.11.003 · Cited by 6
Rodríguez‐Wilhelmi, P., Montes, R., Matsukawa, A., Hurtado, V., Montes, M. C., Hermida, J., & Rocha, E. A. V. (2002) · Experimental and Molecular Pathology · doi:10.1006/exmp.2002.2467 · Cited by 5
Tribl, B., Filipp, D., Bödeker, H., Yu, P. W., Hammerrmüller, I., McKerlie, C., Keim, V., & Sibbald, W. J. (2004) · Pancreas · doi:10.1097/00006676-200407000-00053 · Cited by 5
Decreased circulating elastin peptide levels in humans with sepsis
Faury, G., Wynnychenko, T. M., Cand, F., Léone, M., Jacob, M., Verdetti, J., & Boyle, W. A. (2005) · Pathologie Biologie · doi:10.1016/j.patbio.2004.12.032 · Cited by 5
Cited by
The immunopathology of sepsis and potential therapeutic targets
van der Poll, T., van de Veerdonk, F. L., Scicluna, B. P., & Netea, M. G. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2017.36 · Cited by 1,957
Sepsis: a roadmap for future research
Cohen, J., Vincent, J.-L., Adhikari, N. K. J., Machado, F. R., Angus, D. C., Calandra, T., Jaton, K., Giulieri, S., Delaloye, J., Opal, S., et al. (2015) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(15)70112-x · Cited by 992
Self-citationThe immune system’s role in sepsis progression, resolution, and long-term outcome
Delano, M. J., & Ward, P. A. (2016) · Immunological Reviews · doi:10.1111/imr.12499 · Cited by 880
Mechanisms and treatment of organ failure in sepsis
Lelubre, C., & Vincent, J.-L. (2018) · Nature Reviews Nephrology · doi:10.1038/s41581-018-0005-7 · Cited by 852
Self-citationSepsis-associated encephalopathy
Gofton, T. E., & Young, G. B. (2012) · Nature Reviews Neurology · doi:10.1038/nrneurol.2012.183 · Cited by 821
Metadata
- Authors
- Pierrakos, C., & Vincent, J.-L.
- Venue
- Critical Care
- Published
- 2010-02-09
- Volume
- 14
- Issue
- 1
- Pages
- R15-R15
- ISSN
- 1364-8535 (ISSN-L)
- OpenAlex
- W2127774299
- Cited by
- 1,377
- References
- 208
- FWCI
- 44.87
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
