The Ubiquitin–Proteasome System in Regulation of the Skeletal Muscle Homeostasis and Atrophy: From Basic Science to Disorders

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FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells.

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Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration

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PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

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Back to the Future with Ubiquitin

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During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

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Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

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BMP signaling controls muscle mass

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Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3

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Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice

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Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy

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Ubiquitin Ligase Cbl-b Is a Negative Regulator for Insulin-Like Growth Factor 1 Signaling during Muscle Atrophy Caused by Unloading

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Untitled work

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