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Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery: study protocol for a randomized controlled trial (UPGRADE trial)
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The trial was done according to the previously published trial protocol and statistical analysis plan.
“The trial was done according to the previously published trial protocol and statistical analysis plan.17,18”
Based on an expected reduction in symptomatic gallstone disease from 11% to 5.5% with a two-sided α of 5%, power of 80%, and drop-out of 20%, the trial calculated a total sample size of 980 patients.
“Based on an expected reduction in symptomatic gallstone disease from 11% to 5•5% with a two-sided α of 5%, power of 80%, and drop-out of 20%, we calculated a total sample size of 980 patients.17”
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Cites
Banks, P. A., Bollen, T. L., Dervenis, C., Gooszen, H. G., Johnson, C. D., Sarr, M. G., Tsiotos, G. G., & Vege, S. S. (2013) · Gut · doi:10.1136/gutjnl-2012-302779 · Cited by 7,187
Nelson, D. W., Blair, K. S., & Martin, M. J. (2012) · Archives of Surgery · doi:10.1001/archsurg.2012.1654 · Cited by 128
Stokes, C. S., Gluud, L. L., Casper, M., & Lammert, F. (2014) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2013.11.031 · Cited by 118
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Research works printed but not linked: 40
- Angrisani L, Santonicola A, Iovino P, Formisano G, Buchwald H, Scopinaro N. Bariatric surgery worldwide 2013. Obes Surg. 2015;25(10):1822–32. · DOI
- Jonas E, Marsk R, Rasmussen F, Freedman J. Incidence of postoperative gallstone disease after antiobesity surgery: population-based study from Sweden. Surg Obes Relat Dis. 2010;6(1):54–8. · DOI
- Paumgartner G, Sauerbruch T. Gallstones: pathogenesis. Lancet. 1991;338(8775):1117–21. · DOI
- Shiffman ML, Sugerman HJ, Kellum JM, Brewer WH, Moore EW. Gallstone formation after rapid weight loss: a prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity. Am J Gastroenterol. 1991;86(8):1000–5.
- Plecka Ostlund M, Wenger U, Mattsson F, Ebrahim F, Botha A, Lagergren J. Population-based study of the need for cholecystectomy after obesity surgery. Br J Surg. 2012;99(6):864–9. · DOI
- Nagem R, Lazaro-da-Silva A. Cholecystolithiasis after gastric bypass: a clinical, biochemical, and ultrasonographic 3-year follow-up study. Obes Surg. 2012;22(10):1594–9. · DOI
- Portenier DD, Grant JP, Blackwood HS, Pryor A, McMahon RL, DeMaria E. Expectant management of the asymptomatic gallbladder at roux-en-Y gastric bypass. Surg Obes Relat Dis. 2007;3(4):476–9. · DOI
- Sugerman HJ, Brewer WH, Shiffman ML, Brolin RE, Fobi MA, Linner JH, MacDonald KG, MacGregor AM, Martin LF, Oram-Smith JC, et al. A multicenter, placebo-controlled, randomized, double-blind, prospective trial of prophylactic ursodiol for the prevention of gallstone formation following gastric-bypass-induced rapid weight loss. Am J Surg. 1995;169(1):91–6. discussion 96-97 · DOI · Paper page
- Worobetz LJ, Inglis FG, Shaffer EA. The effect of ursodeoxycholic acid therapy on gallstone formation in the morbidly obese during rapid weight loss. Am J Gastroenterol. 1993;88(10):1705–10.
- Boerlage TC, van de Laar AW, Westerlaken S, Gerdes VE, Brandjes DP. Gastrointestinal symptoms and food intolerance 2 years after laparoscopic roux-en-Y gastric bypass for morbid obesity. Br J Surg. 2017;104(4):393–400. · DOI
- Shiffman ML, Sugerman HJ, Kellum JM, Moore EW. Changes in gallbladder bile composition following gallstone formation and weight reduction. Gastroenterology. 1992;103(1):214–21. · DOI · Paper page
- Kumaravel A, Zelisko A, Schauer P, Lopez R, Kroh M, Stevens T. Acute pancreatitis in patients after bariatric surgery: incidence, outcomes, and risk factors. Obes Surg. 2014;24(12):2025–30. · DOI
- Choi EK, Chiorean MV, Cote GA, El H, II, Ballard D, Fogel EL, Watkins JL, McHenry L, Sherman S, Lehman GA: ERCP via gastrostomy vs. double balloon enteroscopy in patients with prior bariatric roux-en-Y gastric bypass surgery. Surg Endosc 2013, 27(8):2894–2899. · DOI
- Kaafarani HM, Smith TS, Neumayer L, Berger DH, Depalma RG, Itani KM. Trends, outcomes, and predictors of open and conversion to open cholecystectomy in veterans health administration hospitals. Am J Surg. 2010;200(1):32–40. · DOI
- Simopoulos C, Botaitis S, Polychronidis A, Tripsianis G, Karayiannakis AJ. Risk factors for conversion of laparoscopic cholecystectomy to open cholecystectomy. Surg Endosc. 2005;19(7):905–9. · DOI
- Lengyel BI, Panizales MT, Steinberg J, Ashley SW, Tavakkoli A. Laparoscopic cholecystectomy: what is the price of conversion? Surgery. 2012;152(2):173–8. · DOI
- Nuzzo G, Giuliante F, Giovannini I, Ardito F, D'Acapito F, Vellone M, Murazio M, Capelli G. Bile duct injury during laparoscopic cholecystectomy: results of an Italian national survey on 56 591 cholecystectomies. Arch Surg. 2005;140(10):986–92. · DOI
- Waage A, Nilsson M. Iatrogenic bile duct injury: a population-based study of 152 776 cholecystectomies in the Swedish inpatient registry. Arch Surg. 2006;141(12):1207–13. · DOI
- Fobi M, Lee H, Igwe D, Felahy B, James E, Stanczyk M, Fobi N. Prophylactic cholecystectomy with gastric bypass operation: incidence of gallbladder disease. Obes Surg. 2002;12(3):350–3. · DOI
- Warschkow R, Tarantino I, Ukegjini K, Beutner U, Guller U, Schmied BM, Muller SA, Schultes B, Thurnheer M. Concomitant cholecystectomy during laparoscopic roux-en-Y gastric bypass in obese patients is not justified: a meta-analysis. Obes Surg. 2013;23(3):397–407. · DOI · Paper page
- Worni M, Guller U, Shah A, Gandhi M, Shah J, Rajgor D, Pietrobon R, Jacobs DO, Ostbye T. Cholecystectomy concomitant with laparoscopic gastric bypass: a trend analysis of the nationwide inpatient sample from 2001 to 2008. Obes Surg. 2012;22(2):220–9. · DOI · Paper page
- D'Hondt M, Sergeant G, Deylgat B, Devriendt D, Van Rooy F, Vansteenkiste F. Prophylactic cholecystectomy, a mandatory step in morbidly obese patients undergoing laparoscopic roux-en-Y gastric bypass? J Gastrointest Surg. 2011;15(9):1532–6. · DOI
- Li VK, Pulido N, Fajnwaks P, Szomstein S, Rosenthal R, Martinez-Duartez P. Predictors of gallstone formation after bariatric surgery: a multivariate analysis of risk factors comparing gastric bypass, gastric banding, and sleeve gastrectomy. Surg Endosc. 2009;23(7):1640–4. · DOI · Paper page
- Yang H, Petersen GM, Roth MP, Schoenfield LJ, Marks JW. Risk factors for gallstone formation during rapid loss of weight. Dig Dis Sci. 1992;37(6):912–8. · DOI · Paper page
- Shiffman ML, Sugerman HJ, Kellum JH, Brewer WH, Moore EW. Gallstones in patients with morbid obesity. Relationship to body weight, weight loss and gallbladder bile cholesterol solubility. Int J Obes Relat Metab Disord. 1993;17(3):153–8.
- Hempfling W, Dilger K, Beuers U. Systematic review: ursodeoxycholic acid--adverse effects and drug interactions. Aliment Pharmacol Ther. 2003;18(10):963–72. · DOI
- Uy MC, Talingdan-Te MC, Espinosa WZ, Daez ML, Ong JP. Ursodeoxycholic acid in the prevention of gallstone formation after bariatric surgery: a meta-analysis. Obes Surg. 2008;18(12):1532–8. · DOI · Paper page
- Adams LB, Chang C, Pope J, Kim Y, Liu P, Yates A. Randomized, prospective comparison of Ursodeoxycholic acid for the prevention of gallstones after sleeve Gastrectomy. Obes Surg. 2015; · DOI · Paper page
- Kiewiet RM, Durian MF, van Leersum M, Hesp FL, van Vliet AC. Gallstone formation after weight loss following gastric banding in morbidly obese Dutch patients. Obes Surg. 2006;16(5):592–6. · DOI
- Mechanick JI, Youdim A, Jones DB, Timothy Garvey W, Hurley DL, Molly McMahon M, Heinberg LJ, Kushner R, Adams TD, Shikora S, et al. Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient--2013 update: cosponsored by American Association of Clinical Endocrinologists, the Obesity Society, and American Society for Metabolic & bariatric surgery. Surg Obes Relat Dis. 2013;9(2):159–91. · DOI
- Kimura Y, Takada T, Strasberg SM, Pitt HA, Gouma DJ, Garden OJ, Buchler MW, Windsor JA, Mayumi T, Yoshida M, et al. TG13 current terminology, etiology, and epidemiology of acute cholangitis and cholecystitis. Journal of hepato-biliary-pancreatic sciences. 2013;20(1):8–23. · DOI
- The epidemiology of gallstone disease in Rome, Italy. Part II. Factors associated with the disease. The Rome Group for Epidemiology and Prevention of Cholelithiasis (GREPCO). Hepatology (Baltimore, Md) 1988, 8(4):907–913. · DOI
- Marks JW, Stein T, Schoenfield LJ. Natural history and treatment with ursodiol of gallstones formed during rapid loss of weight in man. Dig Dis Sci. 1994;39(9):1981–4. · DOI
- Malone M, Lindstrom J, Gallati C. Impact of change in duration of therapy with Ursodiol after gastric bypass surgery. Pharmacotherapy. 2011;31(10):315e.
- Friedman GD. Natural history of asymptomatic and symptomatic gallstones. Am J Surg. 1993;165(4):399–404. · DOI
- Zhang Z, Peluso MJ, Gross CP, Viscoli CM, Kernan WN. Adherence reporting in randomized controlled trials. Clinical trials (London, England). 2014;11(2):195–204. · DOI
- Rudic JS, Poropat G, Krstic MN, Bjelakovic G, Gluud C. Ursodeoxycholic acid for primary biliary cirrhosis. Cochrane Database Syst Rev. 2012;12:CD000551.
- Sullivan SD, Mauskopf JA, Augustovski F, Jaime Caro J, Lee KM, Minchin M, Orlewska E, Penna P, Rodriguez Barrios JM, Shau WY. Budget impact analysis-principles of good practice: report of the ISPOR 2012 budget impact analysis good practice II task force. Value Health. 2014;17(1):5–14. · DOI
- Coupaye M, Castel B, Sami O, Tuyeras G, Msika S, Ledoux S. Comparison of the incidence of cholelithiasis after sleeve gastrectomy and roux-en-Y gastric bypass in obese patients: a prospective study. Surg Obes Relat Dis. 2015;11(4):779–84. · DOI · Paper page
- van de Laar AW, Dolle MH, de Brauw LM, Bruin SC, Acherman YI. Validating the alterable weight loss (AWL) metric with 2-year weight loss outcome of 500 patients after gastric bypass. Obes Surg. 2014;24(7):1085–9. · DOI
Cited by
Sorted by citations
Mechanick, J. I., Apovian, C., Brethauer, S., Garvey, W. T., Joffe, A. M., Kim, J., Kushner, R. F., Lindquist, R., Pessah-Pollack, R., Seger, J., et al. (2020) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2019.10.025 · Cited by 608
Mechanick, J. I., Apovian, C., Brethauer, S., Garvey, W. T., Joffe, A. M., Kim, J., Kushner, R. F., Lindquist, R., Pessah-Pollack, R., Seger, J., et al. (2019) · Endocrine Practice · doi:10.4158/gl-2019-0406 · Cited by 510
Haal, S., Guman, M. S. S., Boerlage, T. C. C., Acherman, Y. I. Z., de Brauw, L. M., Bruin, S., de Castro, S. M. M., van Hooft, J. E., van de Laar, A. W. J. M., Moes, D. E., et al. (2021) · The Lancet Gastroenterology & Hepatology · doi:10.1016/s2468-1253(21)00301-0 · Cited by 82
Self-citationDai, Y., Luo, B., & Li, W. (2023) · Lipids in Health and Disease · doi:10.1186/s12944-023-01774-7 · Cited by 35
Metadata
- Authors
- Boerlage, T. C. C., Haal, S., Maurits de Brauw, L., Acherman, Y. I. Z., Bruin, S., van de Laar, A. W. J. M., Moes, D. E., van Wagensveld, B. A., de Vries, C. E. E., van Veen, R., Schouten, R., Dijkgraaf, M. G., Fockens, P., Gerdes, V. E. A., & Voermans, R. P.
- Venue
- BMC Gastroenterology
- Published
- 2017-12
- Volume
- 17
- Issue
- 1
- ISSN
- 1471-230X
- PMC
- PMC5738131
- Cited by
- 40
- References
- 3
- Language
- en
- Funders
- Zambon BV
- ZonMw (848015003)
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