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Cited by 35Frailty in Older AdultsBalance, Gait, and Falls PreventionNutrition and Health in Aging

Timed up and go test predicts mortality in older adults in Peru: a population-based cohort study

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Ascencio, Edson J., Cieza-Gómez, Gustavo D., Carrillo-Larco, Rodrigo M., Ortiz, Pedro J.·2022·BMC Geriatrics
DOI 10.1186/s12877-022-02749-6PMC PMC8767748
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Abstract

Background: While there is evidence about stablished risk factors (e.g., raised blood pressure) and higher mortality risk in older population, less has been explored about other functional parameters like the Timed Up and Go test and the Gait Speed in older people at low- and middle-income countries. We aimed to study these mobility tests as predictors of mortality in a population of older people in Peru. Methods: Population-based prospective cohort study (2013–2020). Random sampling of people aged 60+ years in a community of Lima, Peru. Geriatricians conducted all clinical evaluations and laboratory tests were conducted in the local hospital. Participants were sought in the national vital registration system, and we collated cause (ICD-10) and date of death. We conducted a nested forward multivariate Cox proportional hazard model to identify all potential predictors of all-cause, communicable and non-communicable diseases mortality. Results: At baseline, there were 501 older people (mean age 70.6 and 62.8% were women), complete follow-up information was available from 427 people. Mean follow-up time was 46.5 months (SD = 25.3). In multivariate models, the Timed Up and Go test was associated with higher risk of all-cause mortality (HR = 1.05; 95% CI: 1.02–1.09). For cause-specific mortality, history of heart disease (HR = 2.25; 95% CI: 1.07–4.76) and age in years (HR = 1.05; 95% CI: 1.01–1.09) were predictors of non-communicable diseases mortality. Conclusions: In addition to established risk factors for mortality in older population, the Timed Up and Go test, a functional parameter, raised as a relevant predictor of all-cause mortality.

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  • The Timed Up and Go test evaluates mobility in older adults and has been used to assess functional mobility and as a predictor of falls and mortality.

    “The Timed Up and Go (TUG) test evaluates mobility in older adults [134].Also, TUG has been used to assess functional mobility [135] and as a predictor of falls and mortality.”

    From The Seven Methods for the Evaluation of Nutritional Status—ABCDEFG: Narrative Review (2026) · cites this paper as [135]

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Cited by

Sorted by citations

Authors
Ascencio, E. J., Cieza-Gómez, G. D., Carrillo-Larco, R. M., & Ortiz, P. J.
Affiliations
Universidad Peruana Cayetano Heredia (PE)
Corresponding author
Ortiz, Pedro J.
ORCID
Venue
BMC Geriatrics
Publisher
Springer Science and Business Media LLC
Published
2022-01-18
Volume
22
Issue
1
Pages
61-61
ISSN
1471-2318 (ISSN-L)
DOI
10.1186/s12877-022-02749-6
PMC
PMC8767748
OpenAlex
W4205648610
Cited by
35
References
5
Citations by year
2026: 7 · 2025: 12 · 2024: 7 · 2023: 5 · 2022: 4
FWCI
4.00
Type
journal article
Language
en
Open access
Licence
Locations
  • BMC Geriatrics (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Spiral (Imperial College London) (submittedVersion, cc-by)
Funders
Wellcome Trust (214185, 214185/Z/18/Z)
Topics
  • Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
  • Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
Keywords
Timed Up and Go test, walking speed, mortality prediction, older adults, functional mobility, all-cause mortality, non-communicable disease mortality, communicable disease mortality, heart disease
MeSH terms
Aged, Postural Balance, Female, Humans, Peru, Prospective Studies, Time and Motion Studies, Cohort Studies

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