Cited by 62Multiple Sclerosis Research StudiesCancer survivorship and careMindfulness and Compassion Interventions

Symptom changes in multiple sclerosis following psychological interventions: a systematic review

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Pagnini, Francesco, Bosma, Colin M, Phillips, Deborah, Langer, Ellen·2014·BMC Neurology

Abstract

BACKGROUND: Multiple Sclerosis is a disease of the central nervous system involving a variety of debilitating physical, sensory, cognitive and emotional symptoms. This literature review evaluated the impact of psychological interventions on the physiological symptoms associated with the illness. METHODS: A systematic literature search was conducted using Medline, PsycINFO, Scopus, and the Cochrane Library databases, as well as reference lists. Relevant studies were selected and assessed according to a preset protocol. RESULTS: The search produced 220 articles, with 22 meeting inclusion criteria for the review. A total of 5,705 subjects with Multiple Sclerosis were analyzed. Results from the included studies indicate a general improvement in both psychological and physiological outcomes following psychological treatment. The most highly influenced physical symptoms include fatigue, sleep disturbances, pain, and physical vitality. CONCLUSIONS: Findings from the review suggest a positive relationship between psychological interventions and physiological Multiple Sclerosis symptoms. Implications for future research are discussed.

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  1. [10]Langer EJ Mindfulness 1989 Reading, MA Addison-Wesley/Addison Wesley Longman

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Authors
Pagnini, F., Bosma, C. M., Phillips, D., & Langer, E.
Affiliations
  • Università Cattolica del Sacro Cuore (IT)
  • Harvard University (US)
Corresponding author
Pagnini, Francesco
Venue
BMC Neurology
Published
2014-11-30
Volume
14
Issue
1
Pages
222-222
ISSN
1471-2377 (ISSN-L)
OpenAlex
W2142574335
Cited by
62
References
52
Citations by year
2026: 3 · 2025: 2 · 2024: 9 · 2023: 8 · 2022: 5 · 2021: 6 · 2020: 5 · 2019: 5 · 2018: 4 · 2017: 6 · 2016: 8 · 2015: 1
FWCI
0.71
Type
journal article
Language
en
Open access
Locations
  • BMC Neurology (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
  • PubliCatt (Università Cattolica del Sacro Cuore) (submittedVersion, other-oa)
Funders
Fondazione Italiana Sclerosi Multipla
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
Keywords
multiple sclerosis, psychological intervention, symptom change, fatigue, sleep disorders, pain, physical vitality, psychotherapy outcome, physiological symptoms
MeSH terms
Fatigue, Humans, Multiple Sclerosis, Sleep Wake Disorders

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