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Cited by 72Gestational Diabetes Research and ManagementDiabetes, Cardiovascular Risks, and LipoproteinsMaternal and Neonatal Healthcare

Prevalence and risk factors of gestational diabetes mellitus: findings from a universal screening feasibility program in Lima, Peru

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Larrabure-Torrealva, Gloria T., Martinez, Stephanie, Luque-Fernandez, Miguel Angel, Sanchez, Sixto E., Mascaro, Pedro A., Ingar, Hugo, Castillo, Walter, Zumaeta, Rina +5 more·2018·BMC Pregnancy and Childbirth
DOI 10.1186/s12884-018-1904-0PMC PMC6052534
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Abstract

BACKGROUND: Gestational diabetes mellitus (GDM) is a global public health concern with potential implications for the health of a mother and her offspring. However, data on the prevalence and risk factors of GDM in Latin America are scarce. The study was designed to estimate the prevalence of GDM and identify maternal risk factors among Peruvian women. METHODS: A cross-sectional study was conducted among 1300 pregnant women attending a prenatal clinic in Lima, Peru. GDM was diagnosed using an Oral Glucose Tolerance Test (OGTT) performed between 24 and 28 gestational weeks using the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria. Depression status was assessed using the Patient Health Questionnaire-9. Multivariate logistic regression models were used to identify risk factors of GDM. RESULTS: Approximately 16% of pregnant women were diagnosed with GDM. The prevalence of obesity and depression were 24.4 and 10.6%, respectively. After adjusting for confounders, mid-pregnancy obesity was associated with a 1.64-fold increased odds of GDM (OR: 1.64; 95% CI: 1.03-2.61). Participants with a family history of diabetes had a 1.5-fold increased odds of developing GDM (OR: 1.51, 95% CI: 1.10-2.07) as compared to women without this family history. Depression was associated with a 1.54-fold increased odds of GDM (OR: 1.54; 95% CI:1.09-2.17). CONCLUSIONS: GDM is highly prevalent and was associated with maternal obesity, family history of diabetes and antepartum depression among Peruvian women. Intervention programs aimed at early diagnoses and management of GDM need to take maternal obesity, family history of diabetes and antepartum depression into account.

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  • In Peru, a large prospective study using IADPSG/WHO criteria found a 16% gestational diabetes mellitus prevalence among pregnant women.

    “The results presented a 16% GDM prevalence among pregnant women.”

    From Evolution of Gestational Diabetes Mellitus across Continents in 21st Century (2022) · cites this paper as [94]

    The Abstract Results report that approximately 16% of pregnant women were diagnosed with GDM, and the Abstract Methods identify a sample of 1,300 women in Lima assessed using IADPSG criteria. The Methods describe the study as cross-sectional, not prospective, and do not identify the diagnostic criteria as WHO criteria. No page numbers are available in our copy. (LLM, conf=0.86)

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  • In Peru, mid-pregnancy obesity and family history of diabetes had increased odds ratios of gestational diabetes mellitus.

    “Additionally, researchers found that mid-pregnancy obesity, and family history of diabetes, had increased odds ratios of GDM [94].”

    From Evolution of Gestational Diabetes Mellitus across Continents in 21st Century (2022) · cites this paper as [94]

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Authors
Larrabure-Torrealva, G. T., Martinez, S., Luque-Fernandez, M. A., Sanchez, S. E., Mascaro, P. A., Ingar, H., Castillo, W., Zumaeta, R., Grande, M., Motta, V., Pacora, P., Gelaye, B., & Williams, M. A.
Affiliations
  • National University of San Marcos (PE)
  • Harvard University (US)
Corresponding author
Gelaye, Bizu
ORCID
Venue
BMC Pregnancy and Childbirth
Publisher
Springer Science and Business Media LLC
Published
2018-07-18
Volume
18
Issue
1
Pages
303-303
ISSN
1471-2393 (ISSN-L)
DOI
10.1186/s12884-018-1904-0
PMC
PMC6052534
OpenAlex
W2883515392
Cited by
72
References
3
Citations by year
2026: 1 · 2025: 5 · 2024: 12 · 2023: 16 · 2022: 17 · 2021: 8 · 2020: 7 · 2019: 4 · 2018: 1 · 2017: 1
FWCI
5.61
Type
journal article
Language
en
Open access
Licence
Locations
  • BMC Pregnancy and Childbirth (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, other-oa)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, cc-by)
Funders
  • Roche Diagnostic Operations (208617-5074547)
  • National Center on Minority Health and Health Disparities (T37-MD0014490)
Topics
  • Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
Keywords
gestational diabetes mellitus, prevalence, risk factors, maternal obesity, antenatal depression, family history of diabetes, prenatal screening, IADPSG criteria
MeSH terms
Adult, Cross-Sectional Studies, Female, Glucose Tolerance Test, Humans, Medical History Taking, Obesity, Peru, Pregnancy, Risk Factors, Prevalence, Diabetes, Gestational, Risk Assessment, Needs Assessment, Early Diagnosis, Early Medical Intervention

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