Associations of self-reported physical activity and depression in 10,000 Irish adults across harmonised datasets: a DEDIPAC-study
Open accessAbstract
BACKGROUND: Depression is a prevalent, debilitating, and often recurrent mood disorder for which successful first-line treatments remains limited. The purpose of this study was to investigate the cross-sectional associations between self-reported physical activity (PA) and depressive symptoms and status among Irish adults, using two existing datasets, The Irish Longitudinal Study on Ageing (TILDA) and The Mitchelstown Cohort Study. METHODS: The two selected databases were pooled (n = 10,122), and relevant variables were harmonized. PA was measured using the short form International Physical Activity Questionnaire. Depressive symptoms were measured by the Center for Epidemiologic Studies Depression (CES-D) questionnaire. Participants were classified as meeting World Health Organization moderate-to-vigorous PA (MVPA) guidelines or not, and divided into tertiles based on weekly minutes of MVPA. A CES-D score of ≥16 indicated elevated depressive symptoms. Data collection were conducted in 2010-2011. RESULTS: Significantly higher depressive symptoms were reported by females (7.11 ± 7.87) than males (5.74 ± 6.86; p < 0.001). Following adjustment for age, sex, BMI, and dataset, meeting the PA guidelines was associated with 44.7% (95%CI: 35.0 to 52.9; p < 0.001) lower odds of elevated depressive symptoms. Compared to the low PA tertile, the middle and high PA tertiles were associated with 25.2% (95%CI: 8.7 to 38.6; p < 0.01) and 50.8% (95%CI: 40.7 to 59.2; p < 0.001) lower odds of elevated depressive symptoms, respectively. CONCLUSION: Meeting the PA guidelines is associated with lower odds of elevated depressive symptoms, and increased volumes of MVPA are associated with lower odds of elevated depressive symptoms.
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Cross-sectional studies over the past 30 years have suggested that low physical activity is an important risk factor for the development of depression.
“Cross-sectional studies over the past 30 years have suggested that low physical activity is an important risk factor for the development of depression [11, 12].”
From Systematic review and meta-analysis of the effects of exercise on depression in adolescents (2022) · cites this paper as [12]
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Effects of Health-Related Behaviors and Changes on Successful Aging among Indonesian Older People
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Self-citationNeurobehavioral alterations in a mouse model of chronic partial sleep deprivation
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- Authors
- Mc Dowell, C. P., Carlin, A., Capranica, L., Dillon, C., Harrington, J. M., Lakerveld, J., Loyen, A., Ling, F. C. M., Brug, J., MacDonncha, C., & Herring, M. P.
- Affiliations
- University of Ulster (GB)
- Foro Italico University of Rome (IT)
- University College Cork (IE)
- Amsterdam Public Health (NL)
- University of Limerick (IE)
- ORCID
- Venue
- BMC Public Health
- Published
- 2018-07-01
- Volume
- 18
- Issue
- 1
- Pages
- 779-779
- ISSN
- 1471-2458 (ISSN-L)
- PMC
- PMC6026508
- OpenAlex
- W2809086346
- Cited by
- 41
- References
- 59
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 4 · 2023: 2 · 2022: 6 · 2021: 9 · 2020: 7 · 2019: 5 · 2018: 2
- FWCI
- 3.94
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Public Health (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Cork Open Research Archive (University College Cork, Ireland) (publishedVersion, cc-by)
- Ulster University Research Portal (Ulster University) (publishedVersion, cc-by)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion, other-oa)
- Bournemouth University Research Online (Bournemouth University) (acceptedVersion)
- Northumbria Research Link (Northumbria University) (acceptedVersion)
- Arrow@dit (Dublin Institute of Technology) (acceptedVersion)
- University of Limerick Institutional Repository (University of Limerick) (acceptedVersion, other-oa)
- Victoria University Research Repository (Victoria University) (submittedVersion, cc-by)
- Arrow@dit (Dublin Institute of Technology) (submittedVersion, cc-by-nc-sa)
- Cork Open Research Archive (University College Cork, Ireland) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Figshare (submittedVersion, cc-by-nc-sa)
- Pure Amsterdam UMC (submittedVersion, cc-by)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Funders
- Health Research Board (TILDA-2017-1)
- University College Cork
- ZonMw
- Ministero dell’Istruzione, dell’Università e della Ricerca ((PRIN 2010), 2010KL2Y73_003, B84G14000040008, P.R.I.N. 2010/11)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Health › Health disparities and outcomes
- Keywords
- physical activity, depression, depressive symptoms, moderate-to-vigorous physical activity, physical activity guidelines, sex differences, Irish adults, Irish Longitudinal Study on Ageing
- MeSH terms
- Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Depression, Female, Humans, Ireland, Longitudinal Studies, Male, Middle Aged, Cohort Studies, Exercise, Guidelines as Topic, Guideline Adherence, Self Report, Datasets as Topic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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