The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Macrophage activation and polarization in post-infarction cardiac remodeling
Open accessAbstract
Adverse cardiac remodeling leads to impaired ventricular function and heart failure, remaining a major cause of mortality and morbidity in patients with acute myocardial infarction. It have been shown that, even if all the recommended therapies for ST-segment elevation myocardial infarction are performed, one third of patients undergoes progressive cardiac remodeling that represents morphological basis for following heart failure. The need to extend our knowledge about factors leading to different clinical scenarios of myocardial infarction and following complications has resulted in a research of immuno-inflammatory pathways and molecular activities as the basis for post-infarction remodeling. Recently, macrophages (cells of the innate immune system) have become a subject of scientific interest under both normal and pathological conditions. Macrophages, besides their role in host protection and tissue homeostasis, play an important role in pathophysiological processes induced by myocardial infarction. In this article we summarize data about the function of monocytes and macrophages plasticity in myocardial infarction and outline potential role of these cells as effective targets to control processes of inflammation, cardiac remodeling and healing following acute coronary event.
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Cites
The SOLVD Investigators* (1991) · New England Journal of Medicine · doi:10.1056/nejm199108013250501 · Cited by 8,029
The chemokine system in diverse forms of macrophage activation and polarization
MANTOVANI, A., SICA, A., SOZZANI, S., ALLAVENA, P., VECCHI, A., & LOCATI, M. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.09.015 · Cited by 6,534
Macrophage plasticity and polarization: in vivo veritas
Sica, A., & Mantovani, A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci59643 · Cited by 6,335
Alternative activation of macrophages
Gordon, S. (2003) · Nature Reviews Immunology · doi:10.1038/nri978 · Cited by 6,189
MANTOVANI, A., SOZZANI, S., LOCATI, M., ALLAVENA, P., & SICA, A. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)02302-5 · Cited by 5,528
Protective and pathogenic functions of macrophage subsets
Murray, P. J., & Wynn, T. A. (2011) · Nature Reviews Immunology · doi:10.1038/nri3073 · Cited by 5,269
Macrophage biology in development, homeostasis and disease
Wynn, T. A., Chawla, A., & Pollard, J. W. (2013) · Nature · doi:10.1038/nature12034 · Cited by 4,684 · cited 1×
“cing their functions, is their phenotypic and functional plasticity [39, 40].”
BackgroundAlternative activation of macrophages: mechanism and functions
Gordon, S., & Martinez, F. O. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.007 · Cited by 4,197
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
Biswas, S. K., & Mantovani, A. (2010) · Nature Immunology · doi:10.1038/ni.1937 · Cited by 3,840
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
Schulz, C., Perdiguero, E. G., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., et al. (2012) · Science · doi:10.1126/science.1219179 · Cited by 2,578
Cited by
Ma, Y., Mouton, A. J., & Lindsey, M. L. (2018) · Translational Research · doi:10.1016/j.trsl.2017.10.001 · Cited by 405
Kologrivova, I., Shtatolkina, M., Suslova, T., & Ryabov, V. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.664457 · Cited by 317
Self-citationMapping macrophage polarization over the myocardial infarction time continuum
Mouton, A. J., DeLeon-Pennell, K. Y., Rivera Gonzalez, O. J., Flynn, E. R., Freeman, T. C., Saucerman, J. J., Garrett, M. R., Ma, Y., Harmancey, R., & Lindsey, M. L. (2018) · Basic Research in Cardiology · doi:10.1007/s00395-018-0686-x · Cited by 309
Immune Cells and Immunotherapy for Cardiac Injury and Repair
Rurik, J. G., Aghajanian, H., & Epstein, J. A. (2021) · Circulation Research · doi:10.1161/circresaha.121.318005 · Cited by 265
Han, J., Kim, Y. S., Lim, M.-Y., Kim, H. Y., Kong, S., Kang, M., Choo, Y. W., Jun, J. H., Ryu, S., Jeong, H.-Y., et al. (2018) · ACS Nano · doi:10.1021/acsnano.7b09107 · Cited by 258
Metadata
- Authors
- Gombozhapova, A., Rogovskaya, Y., Shurupov, V., Rebenkova, M., Kzhyshkowska, J., Popov, S. V., Karpov, R. S., & Ryabov, V.
- Venue
- Journal of Biomedical Science
- Published
- 2017-02-07
- Volume
- 24
- Issue
- 1
- Pages
- 13-13
- ISSN
- 1021-7770 (ISSN-L)
- 1423-0127
- OpenAlex
- W2587273184
- Cited by
- 175
- References
- 25
- FWCI
- 12.68
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Gombozhapova, A., Rogovskaya, Y., Shurupov, V., Rebenkova, M., Kzhyshkowska, J., Popov, S. V., Karpov, R. S., & Ryabov, V. (2017). Macrophage activation and polarization in post-infarction cardiac remodeling. Journal of Biomedical Science. https://doi.org/10.1186/s12929-017-0322-3
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
