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Centella Asiatica Improves Memory and Promotes Antioxidative Signaling in 5XFAD Mice

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Luteolin alleviates methamphetamine-induced neurotoxicity by suppressing PI3K/Akt pathway-modulated apoptosis and autophagy in rats

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TBHQ-Overview of Multiple Mechanisms against Oxidative Stress for Attenuating Methamphetamine-Induced Neurotoxicity

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TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways

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The Crosstalk Between Neurons and Glia in Methamphetamine-Induced Neuroinflammation

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Methamphetamine-induced alterations in intestinal mucosal barrier function occur via the microRNA-181c/ TNF-α/tight junction axis

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Asiatic acid inhibits cardiac fibrosis throughNrf2/HO-1 and TGF-β1/Smads signaling pathways in spontaneous hypertension rats

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Blood-Brain Barrier Permeability of Asiaticoside, Madecassoside and Asiatic Acid in Porcine Brain Endothelial Cell Model

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K284-6111 alleviates memory impairment and neuroinflammation in Tg2576 mice by inhibition of Chitinase-3-like 1 regulating ERK-dependent PTX3 pathway

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The Role of Oxidative Stress and Inflammation in the Pathogenesis and Treatment of Vascular Dementia

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Targeting STATs in neuroinflammation: The road less traveled!

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Research Progress on Anti-Inflammatory Effects and Related Mechanisms of Astragalin

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Asiatic Acid Inhibits OVX-Induced Osteoporosis and Osteoclastogenesis Via Regulating RANKL-Mediated NF-κb and Nfatc1 Signaling Pathways

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Neuroprotective effect of nose-to-brain delivery of Asiatic acid in solid lipid nanoparticles and its mechanisms against memory dysfunction induced by Amyloid Beta1-42 in mice

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Luteolin Alleviates Methamphetamine-Induced Hepatotoxicity by Suppressing the p53 Pathway-Mediated Apoptosis, Autophagy, and Inflammation in Rats

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Apamin Suppresses LPS-Induced Neuroinflammatory Responses by Regulating SK Channels and TLR4-Mediated Signaling Pathways

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Asiatic acid: a review on its polypharmacological properties and therapeutic potential against various Maladies

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Brain Renin–Angiotensin System Blockade Attenuates Methamphetamine-Induced Hyperlocomotion and Neurotoxicity

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MicroRNA‐Enriched Plant‐Derived Exosomes Alleviate Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota

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Asiatic acid and its derivatives: Pharmacological insights and applications

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Activation of proline biosynthesis is critical to maintain glutamate homeostasis during acute methamphetamine exposure

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Effects of Apamin on MPP+-Induced Calcium Overload and Neurotoxicity by Targeting CaMKII/ERK/p65/STAT3 Signaling Pathways in Dopaminergic Neuronal Cells

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Lupenone Protects Neuroblastoma SH-SY5y Cells Against Methamphetamine-Induced Apoptotic Cell Death via PI3K/Akt/mTOR Signaling Pathway

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Elevated serum levels of TNF‐α, IL‐6, and IL‐18 in chronic methamphetamine users

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Fine particulate matter induces endoplasmic reticulum stress-mediated apoptosis in human SH-SY5Y cells

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METH-Induced Neurotoxicity Is Alleviated by Lactulose Pretreatment Through Suppressing Oxidative Stress and Neuroinflammation in Rat Striatum

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Asiatic acid ameliorates doxorubicin-induced cardiotoxicity by promoting FPN-mediated iron export and inhibiting ferroptosis

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Tooth Loss Induces Memory Impairment and Gliosis in App Knock-In Mouse Models of Alzheimer’s Disease

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Tumor necrosis factor-α promotes lipolysis and reduces insulin sensitivity by activating nuclear factor kappa B and c-Jun N-terminal kinase in primary bovine adipocytes

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MiR-142a-3p and miR-155-5p reduce methamphetamine-induced inflammation: Role of the target protein Peli1

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Role of Microglia in Psychostimulant Addiction

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Asiatic Acid Glucosamine Salt Alleviates Ultraviolet B‐induced Photoaging of Human Dermal Fibroblasts and Nude Mouse Skin

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Pentacyclic triterpenoids: diversity, distribution and their propitious pharmacological potential

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Cholecystokinin-8 attenuates methamphetamine-induced inflammatory activation of microglial cells through CCK2 receptor

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Asiatic Acid Inhibits Nasopharyngeal Carcinoma Cell Viability and Migration via Suppressing STAT3 and Claudin-1

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Asiatic acid, an active substance of Centella asiatica, presynaptically depresses glutamate release in the rat hippocampus

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Exercise modulates central and peripheral inflammatory responses and ameliorates methamphetamine-induced anxiety-like symptoms in mice

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Ropivacaine-loaded hydrogels for prolonged relief of chemotherapy-induced peripheral neuropathic pain and potentiated chemotherapy

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Biological role of mitochondrial TLR4‐mediated NF‐κB signaling pathway in central nervous system injury

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Methamphetamine Exposure in Adolescent Impairs Memory of Mice in Adulthood Accompanied by Changes in Neuroplasticity in the Dorsal Hippocampus

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GKT136901 protects primary human brain microvascular endothelial cells against methamphetamine-induced blood-brain barrier dysfunction

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LincRNA-Cox2 regulates IL6/JAK3/STAT3 and NF-κB P65 pathway activation in Listeria monocytogenes-infected RAW264.7 cells

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Natural Products in Modulating Methamphetamine-Induced Neuronal Apoptosis

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Apigenin ameliorates imiquimod-induced psoriasis in C57BL/6J mice by inactivating STAT3 and NF-κB

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Urotensin receptor antagonist urantide improves atherosclerosis-related kidney injury by inhibiting JAK2/STAT3 signaling pathway in rats

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Fucoxanthin alleviates methamphetamine-induced neurotoxicity possibly via the inhibition of interaction between Keap1 and Nrf2

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Effects of manganese on microglia M1 / M2 polarization and SIRT1 ‐mediated transcription of STAT3 ‐dependent genes in mouse

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GPx-1-encoded adenoviral vector attenuates dopaminergic impairments induced by methamphetamine in GPx-1 knockout mice through modulation of NF-κB transcription factor

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MicroRNAs in Methamphetamine-Induced Neurotoxicity and Addiction

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Hippocampal blood–brain barrier of methamphetamine self‐administering HIV‐1 transgenic rats

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S100A1 expression is increased in spinal cord injury and promotes inflammation, oxidative stress and apoptosis of PC12 cells induced by LPS via ERK signaling

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TAK1 Improves Cognitive Function via Suppressing RIPK1-Driven Neuronal Apoptosis and Necroptosis in Rats with Chronic Hypertension

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Neuroprotective prospectives of triterpenoids

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PI3K/AKT/mTOR, NF-κB and ERS pathway participated in the attenuation of H2O2-induced IPEC-J2 cell injury by koumine

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Translocator Protein 18 kDa (TSPO) as a Novel Therapeutic Target for Chronic Pain

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Asiatic acid rescues intestinal tissue by suppressing molecular, biochemical, and histopathological changes associated with the development of ulcerative colitis

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Methamphetamine-mediated astrocytic pyroptosis and neuroinflammation involves miR-152–NLRP6 inflammasome signaling axis

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Aconiti lateralis Radix Praeparata inhibits Alzheimer’s disease by regulating the complex regulation network with the core of GRIN1 and MAPK1

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Atractylodin Induces Apoptosis and Inhibits the Migration of A549 Lung Cancer Cells by Regulating ROS-Mediated Signaling Pathways

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Asiatic Acid, Corosolic Acid, and Maslinic Acid Interfere with Intracellular Trafficking and N-Linked Glycosylation of Intercellular Adhesion Molecule-1

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The interaction between central and peripheral immune systems in methamphetamine use disorder: current status and future directions

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Assessing the neurotoxic risks of triethyl citrate in daily environmental exposure using network toxicology and molecular docking

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6,7,4′-Trihydroxyflavanone Prevents Methamphetamine-Induced T Cell Deactivation by Protecting the Activated T Cells from Apoptosis

Lee, H., & Jeong, G. (2021) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x21500051 · Cited by 12 · see citing works

Asiatic acid alleviates Ang-II induced cardiac hypertrophy and fibrosis via miR-126/PIK3R2 signaling

Li, H., Tian, X., Ruan, Y., Xing, J., & Meng, Z. (2021) · Nutrition & Metabolism · doi:10.1186/s12986-021-00596-7 · Cited by 12 · see citing works

Oral Asiatic Acid Improves Cognitive Function and Modulates Antioxidant and Mitochondrial Pathways in Female 5xFAD Mice

Varada, S., Chamberlin, S. R., Bui, L., Brandes, M. S., Gladen-Kolarsky, N., Harris, C., Hack, W. R., Neff, C. J., Brumbach, B. H., Soumyanath, A., et al. (2025) · Nutrients · doi:10.3390/nu17040729 · Cited by 11 · see citing works

Network Pharmacology Analysis and Experimental Validation to Explore the Anti-inflammatory Mechanism of Asiatic Acid on Alcoholic Steatohepatitis

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EGFR mediated the renal cell apoptosis in rhabdomyolysis-induced model via upregulation of autophagy

Sun, T., Wu, D., Deng, Y., & Zhang, D. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.121050 · Cited by 11 · see citing works

Anxiolytic-like effects of the ethanol extract of Magnolia obovata leaves through its effects on GABA-benzodiazepine receptor and neuroinflammation.

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Atractylodin: An Alkyne Compound with Anticancer Potential

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Single-Cell RNA-Seq Uncovers Robust Glial Cell Transcriptional Changes in Methamphetamine-Administered Mice

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Gynura bicoloraqueous extract attenuated H2O2induced injury in PC12 cells

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Asiatic acid inhibits osteosarcoma cell migration and invasion via the AKT / Sp1 / MMP1 axis

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Thioredoxin-1 Protects Spinal Cord from Demyelination Induced by Methamphetamine through Suppressing Endoplasmic Reticulum Stress and Inflammation

Yang, L., Guo, Y., Huang, M., Wu, X., Li, X., Chen, G., Li, Y., & Bai, J. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00049 · Cited by 10 · see citing works

Role of alpha-synuclein phosphorylation at Serine 129 in methamphetamine-induced neurotoxicity in vitro and in vivo

Ding, J., Wang, Y., Huang, J. A., Lian, Y., Meng, Y., Li, C., He, Y., & Qiu, P. (2020) · Neuroreport · doi:10.1097/wnr.0000000000001495 · Cited by 10 · see citing works

Methamphetamine: Mechanism of Action and Chinese Herbal Medicine Treatment for Its Addiction

Zeng, R., Pu, H., Zhang, X., Yao, M., & Sun, Q. (2023) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-023-3635-y · Cited by 10 · see citing works

5-HTP decreases goat mammary epithelial cells apoptosis through MAPK/ERK/Bcl-3 pathway

Zhao, H., Chen, S., Hu, K., Zhang, Z., Yan, X., Gao, H., Du, W., & Zheng, H. (2020) · Gene · doi:10.1016/j.gene.2020.145240 · Cited by 10 · see citing works

Asiatic Acid Alleviates LPS‐Induced Pyroptosis and Endoplasmic Reticulum Stress‐Mediated Apoptosis via Inhibiting the HMGB1/TLR4/NF‐κB Pathway in Broiler Hepatocytes

Qiu, W., Jiang, W., Su, Y., Huang, H., Ye, J., Wang, R., Tang, Z., & Su, R. (2024) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.14070 · Cited by 9 · see citing works

Resveratrol Attenuates the Disruption of Lipid Metabolism Observed in APP/PS1 Mouse Brains and Cultured Primary Neurons Exposed to Aβ.

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Neuroprotective Effects of Zerumbone on H 2 O 2 -Induced Oxidative Injury in Human Neuroblastoma SH-SY5Y Cells

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Asiatic acid prevents glucocorticoid-induced femoral head osteonecrosis via PI3K/AKT pathway

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The neuroprotective and anti-neuroinflammatory effects of ramalin synthetic derivatives in BV2 and HT22 cells

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Additional file 5: Figure S5. of Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway

Park, J.-H., Seo, Y., Jang, J.-H., Jeong, C.-H., Lee, S., & Park, B. (2017) · Figshare · doi:10.6084/m9.figshare.5691790

Additional file 3: Figure S3. of Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway

Park, J.-H., Seo, Y., Jang, J.-H., Jeong, C.-H., Lee, S., & Park, B. (2017) · Figshare · doi:10.6084/m9.figshare.5691751

Additional file 2: Figure S2. of Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway

Park, J.-H., Seo, Y., Jang, J.-H., Jeong, C.-H., Lee, S., & Park, B. (2017) · Figshare · doi:10.6084/m9.figshare.5691730

Additional file 1: Figure S1. of Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway

Park, J.-H., Seo, Y., Jang, J.-H., Jeong, C.-H., Lee, S., & Park, B. (2017) · Figshare · doi:10.6084/m9.figshare.5691703

Additional file 4: Figure S4. of Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway

Park, J.-H., Seo, Y., Jang, J.-H., Jeong, C.-H., Lee, S., & Park, B. (2017) · Figshare · doi:10.6084/m9.figshare.5691766