The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.
Challenges and emerging directions in single-cell analysis
Open accessAbstract
Single-cell analysis is a rapidly evolving approach to characterize genome-scale molecular information at the individual cell level. Development of single-cell technologies and computational methods has enabled systematic investigation of cellular heterogeneity in a wide range of tissues and cell populations, yielding fresh insights into the composition, dynamics, and regulatory mechanisms of cell states in development and disease. Despite substantial advances, significant challenges remain in the analysis, integration, and interpretation of single-cell omics data. Here, we discuss the state of the field and recent advances and look to future opportunities.
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Cites
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Kester, L., & van Oudenaarden, A. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.04.014 · Cited by 375
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Metadata
- Authors
- Yuan, G.-C., Cai, L., Elowitz, M., Enver, T., Fan, G., Guo, G., Irizarry, R., Kharchenko, P., Kim, J., Orkin, S., Quackenbush, J., Saadatpour, A., Schroeder, T., Shivdasani, R., & Tirosh, I.
- Venue
- Genome Biology
- Published
- 2017-05-08
- Volume
- 18
- Issue
- 1
- Pages
- 84-84
- ISSN
- 1465-6906 (ISSN-L)
- 1474-760X
- OpenAlex
- W2612758576
- Cited by
- 341
- References
- 94
- FWCI
- 13.10
- Type
- journal article
- Language
- en
- Open access
- gold
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- Yuan, G.-C., Cai, L., Elowitz, M., Enver, T., Fan, G., Guo, G., Irizarry, R., Kharchenko, P., Kim, J., Orkin, S., Quackenbush, J., Saadatpour, A., Schroeder, T., Shivdasani, R., & Tirosh, I. (2017). Challenges and emerging directions in single-cell analysis. Genome Biology. https://doi.org/10.1186/s13059-017-1218-y
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