The DOI matches its Crossref record; 91 of the 91 references it cites were found in a registry or an index.
Circulating microRNAs as potential cancer biomarkers: the advantage and disadvantage
Open accessAbstract
MicroRNAs are endogenous single-stranded non-coding small RNA molecules that can be secreted into the circulation and exist stably. They usually exhibit aberrant expression under different physiological and pathological conditions. Recently, differentially expressed circulating microRNAs were focused on as potential biomarkers for cancer screening. We herein review the role of circulating microRNAs for cancer diagnosis, tumor subtype classification, chemo- or radio-resistance monitoring, and outcome prognosis. Moreover, circulating microRNAs still have several issues hindering their reliability for the practical clinical application. Future studies need to elucidate further potential application of circulating microRNAs as specific and sensitive markers for clinical diagnosis or prognosis in cancers.
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Cited by
Trials and Tribulations of MicroRNA Therapeutics
Seyhan, A. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031469 · Cited by 381
Therapeutic Cancer Vaccines—T Cell Responses and Epigenetic Modulation
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Metadata
- Authors
- Wang, H., Peng, R., Wang, J., Qin, Z., & Xue, L.
- Venue
- Clinical Epigenetics
- Published
- 2018-04-23
- Volume
- 10
- Issue
- 1
- Pages
- 59-59
- ISSN
- 1868-7075 (ISSN-L)
- 1868-7083
- OpenAlex
- W2804641693
- Cited by
- 527
- References
- 91
- FWCI
- 16.87
- Type
- journal article
- Language
- en
- Open access
- gold
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- Wang, H., Peng, R., Wang, J., Qin, Z., & Xue, L. (2018). Circulating microRNAs as potential cancer biomarkers: the advantage and disadvantage. Clinical Epigenetics. https://doi.org/10.1186/s13148-018-0492-1
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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