Cited by 183Neurotransmitter Receptor Influence on BehaviorTreatment of Major DepressionStress Responses and Cortisol

The DOI matches its Crossref record; 122 of the 122 references it cites were found in a registry or an index.

Sex differences in mood disorders: perspectives from humans and rodent models

Open access

Seney, Marianne L, Sibille, Etienne·2014·Biology of Sex Differences

DOI 10.1186/s13293-014-0017-3PMC PMC4268901

Open this paper in CoChat — free account Open PDF

Abstract

Mood disorders are devastating, often chronic illnesses characterized by low mood, poor affect, and anhedonia. Notably, mood disorders are approximately twice as prevalent in women compared to men. If sex differences in mood are due to underlying biological sex differences, a better understanding of the biology is warranted to develop better treatment or even prevention of these debilitating disorders. In this review, our goals are to: 1) summarize the literature related to mood disorders with respect to sex differences in prevalence, 2) introduce the corticolimbic brain network of mood regulation, 3) discuss strategies and challenges of modeling mood disorders in mice, 4) discuss mechanisms underlying sex differences and how these can be tested in mice, and 5) discuss how our group and others have used a translational approach to investigate mechanisms underlying sex differences in mood disorders in humans and mice.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1186/s13293-014-0017-3

Cites

122 of 122 references verified0 citation errors · 0 not checkable

Statistics

Figure 1 A novel model depicting a dynamic balance between sex chromosome complement and circulating testosterone on anxiety (black dotted line). A conventional interpretation in the sex difference field is that XY sex chromosome complement may exert a compensatory effect to reduce differences otherwise induced by circulating testosterone or vice versa. Data outlined in this review suggests that this is also the case for the regulation of mood and anxiety-like behaviors. Specifically, while male sex chromosome complement causes an increase in anxiety-like behavior, this effect is opposed by testosterone’s antianxiety effect. While sex chromosome complement appears to be acting via control of gene expression, we hypothesize that testosterone affects the activity of certain inhibitory GABA cell types (e.g., SST cells).CC BY · PubMed Central

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391
How do you feel — now? The anterior insula and human awareness
(Bud) Craig, A. D. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2555 · Cited by 6,657 · cited 1×
“Interestingly, neuroimaging studies show that features of sgACC dysfunction in MDD are sexually dimorphic, with women exhibiting higher levels of reactivity compared to males [33-35].”
Background
Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
Murray, C. J., & Lopez, A. D. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07495-8 · Cited by 4,492 · cited 1×
“In addition to the psychological stress on patients and families, MDD contributes to the development and progression of systemic and organ diseases [2-5].”
Background
Deep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059
A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif
Sinclair, A. H., Berta, P., Palmer, M. S., Hawkins, J. R., Griffiths, B. L., Smith, M. J., Foster, J. W., Frischauf, A., Lovell-Badge, R. H., & Goodfellow, P. N. (1990) · Nature · doi:10.1038/346240a0 · Cited by 3,234
Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions
Krishnan, V., Han, M.-H., Graham, D. L., Berton, O., Renthal, W., Russo, S. J., LaPlant, Q., Graham, A., Lutter, M., Lagace, D. C., et al. (2007) · Cell · doi:10.1016/j.cell.2007.09.018 · Cited by 2,307 · cited 1×
“, [54]).”
Male development of chromosomally female mice transgenic for Sry
Koopman, P. A., Gubbay, J., Vivian, N., Goodfellow, P. N., & Lovell-Badge, R. H. (1991) · Nature · doi:10.1038/351117a0 · Cited by 2,193
Major depressive disorder
Belmaker, R. H., & Agam, G. (2008) · New England Journal of Medicine · doi:10.1056/nejmra073096 · Cited by 2,166
National Health and Nutrition Examination Survey
Rothwell, C. J. (2009) · Springer eBooks · doi:10.1007/978-0-387-78665-0_6177 · Cited by 2,093
5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression
Pezawas, L., Meyer-Lindenberg, A., Drabant, E. M., Verchinski, B. A., Munoz, K. E., Kolachana, B. S., Egan, M. F., Mattay, V. S., Hariri, A. R., & Weinberger, D. R. (2005) · Nature Neuroscience · doi:10.1038/nn1463 · Cited by 1,980

Show all 122 references

Research works printed but not linked: 1

WHO:World Health Organization - The Global Burden of Disease - 2004 Update. WHO Library, Geneva, Switzerland; 2004.

Sorted by citations

Items 101–183 of 183

A Glimpse Into the Sexual Dimorphisms in Major Depressive Disorder Through Epigenetic Studies
Cahill, B., Poelker-Wells, S., Prather, J. F., & Li, Y. (2021) · Frontiers in Neural Circuits · doi:10.3389/fncir.2021.768571 · Cited by 11
Acute stress reveals different impacts in male and female Zdhhc7-deficient mice
Kerkenberg, N., Hohoff, C., Zhang, M., Lang, I., Schettler, C., Ponimaskin, E. G., Wachsmuth, L., Faber, C., Baune, B. T., & Zhang, W. (2021) · Brain Structure and Function · doi:10.1007/s00429-021-02275-y · Cited by 9
Mental rotation, episodic memory, and executive control: Possible effects of biological sex and oral contraceptive use
Jensen, A., Thériault, K., Yılmaz, E., Pon, E., & Davidson, P. S. R. (2023) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2023.107720 · Cited by 9
Genetic and Epigenetic Mechanisms Linking Pain and Psychiatric Disorders
Swiergiel, A. H., Juszczak, G. R., & Stankiewicz, A. M. (2015) · Modern trends in psychiatry · doi:10.1159/000435937 · Cited by 9
Screen time trajectories and psychosocial well-being among Chinese adolescents: a longitudinal study
Wang, W., Jiang, W., Zhu, L., Lu, C., Li, Y., Lai, W., & Guo, L. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-06329-3 · Cited by 8
Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines
Moudio, S., Willis, A., Pytka, K., Abulkassim, R., Brett, R. R., Webster, J. F., Wozny, C., Barbour, M., Jiang, H., Watson, D. G., et al. (2021) · Psychopharmacology · doi:10.1007/s00213-021-06040-1 · Cited by 8
Profile of a short-acting κ-antagonist, LY2795050, on self-grooming behaviors, forced swim test and locomotor activity: sex comparison in mice
Butelman, E. R., Baynard, C., McElroy, B. D., Prisinzano, T. E., & Kreek, M. J. (2021) · Journal of Psychopharmacology · doi:10.1177/0269881121996883 · Cited by 8
Gender differences in symptom profiles of individuals being treated for mood disorders
Weiss, S. J., Nagle-Yang, S. M., Flynn, H. A., Cooper, B. A., Muzik, M., Simeonova, D. I., & Özerdem, A. (2025) · Journal of Mood and Anxiety Disorders · doi:10.1016/j.xjmad.2025.100152 · Cited by 11
Qualitative Approaches to the Study of Substance and Behavioral Addictions
Simpson, K. A., & Bluthenthal, R. N. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.013 · Cited by 10
Ketamine and olanzapine alter behaviour and prefrontal-cortex BDNF differentially in male and female rats
Manooki, K., Gholami, M., Eslami, M., Vaseghi, S., & Yekta, B. G. (2025) · Scientific Reports · doi:10.1038/s41598-025-15499-3 · Cited by 6
Gender differences in cigarette smoking cessation attempts among adults who smoke and drink alcohol at high levels: Findings from the 2018–2020 International Tobacco Control Four Country Smoking and Vaping Surveys
Liu, C., Yong, H., Gravely, S. M. L., East, K. A., Kasza, K. A., GARTNER, C. E., Cummings, K. M., & Fong, G. T. (2023) · Addictive Behaviors · doi:10.1016/j.addbeh.2023.107817 · Cited by 6
The effect of sleep medications on prospective and retrospective memory: a population-based study
Dokkedal‐Silva, V., Oliveira, M. G. M., Galduróz, J. C. F., Tufik, S., & Andersen, M. L. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110043 · Cited by 6
Five-factor personality model versus affective temperaments: a study in a nonclinical Polish sample
Oniszczenko, W., & Stanisławiak, E. (2019) · Current Issues in Personality Psychology · doi:10.5114/cipp.2019.82751 · Cited by 6
Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant DefencesPreprint
Maes, M. H. J., Congio, A. C., Moraes, J. B., Bonifácio, K. L., Barbosa, D. S., Vargas, H. O., Morris, G., Puri, B. K., Michelin, A. P., & Nunes, S. O. V. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/397711 · Cited by 6
Correction: Novel polygenic risk score as a translational tool linking depression-related changes in the corticolimbic transcriptome with neural face processing and anhedonic symptoms
Marečková, K., Hawco, C. S., Santos, F. C. D., Bakht, A., Calarco, N., Miles, A. E., Voineskos, A. N., Sibille, E. L., Hariri, A. R., & Nikolova, Y. S. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01277-y · Cited by 6
Self-citation
Impact of adolescent high-fat diet and psychosocial stress on neuroendocrine stress responses and binge eating behavior in adult male Lewis rats
Sierra, J., Simon, T. B., Hilal, D. A., Torres, Y. A., Santiago, J. M., & Figueroa, J. D. (2025) · Hormones and Behavior · doi:10.1016/j.yhbeh.2025.105744 · Cited by 5
Substance and Behavioral Addictions Assessment Instruments
Grigsby, T. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.012 · Cited by 6
The relationship between cobalamin and folate below the cutoff values on anxiety and insomnia symptoms: Findings from the 8-year longitudinal EPISONO study
Cavalcante‐Silva, V., Vallim, J. R. D. S., de Oliveira, A. C., D’Almeida, V., Tufik, S., & Andersen, M. L. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.119968 · Cited by 4
Sex differences in functional and structural alterations of hippocampus region in chronic pain: a DTI and resting-state fMRI study
Zhou, J.-Z., Deng, J. F., Luo, D., Mai, J.-W., Wu, J., Duan, Y.-J., Dong, B., Xin, W., Xu, T., & Wei, J. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1428666 · Cited by 5
Variation in moment-to-moment brain state engagement follows a consistent trajectory during development
Ye, J., Tejavibulya, L., Dai, W., Cope, L. M., Hardee, J. E., Heitzeg, M. M., Lichenstein, S. D., Yip, S. W., Banaschewski, T., Baker, G. J., et al. (2025) · Neuron · doi:10.1016/j.neuron.2025.08.020 · Cited by 9
Prevention and Treatment of Sex Addiction
Reid, R. C., Grubbs, J. B., & Kraus, S. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.025 · Cited by 4
The effect of Blastocystis sp. and Dientamoeba fragilis on psychological symptom severity in a sample of clinically diverse males and females
Ganci, M., Butt, H., Tyrrell, J., Suleyman, E., & Ball, M. (2021) · Current Psychology · doi:10.1007/s12144-021-01700-z · Cited by 4
Variation in moment-to-moment brain state engagement changes across development and contributes to individual differences in executive functionPreprint
Ye, J., Tejavibulya, L., Dai, W.-S., Cope, L., Hardee, J., Heitzeg, M., Lichenstein, S., Yip, S., Banaschewski, T., Baker, G. J., et al. (2024) · bioRxiv · doi:10.1101/2024.09.06.611627 · Cited by 3
Neuro-Inflammatory and Behavioral Changes Are Selectively Reversed by Sceletium tortuosum (Zembrin®) and Mesembrine in Male Rats Subjected to Unpredictable Chronic Mild Stress
Gericke, J., Steyn, S. F., Viljoen, F. P., & Harvey, B. H. (2025) · Cells · doi:10.3390/cells14131029 · Cited by 3
Neurogliovascular alterations in brain pathologies across lifespan
Daigle, B., Bevilacqua, L. M., Noël, V. P., Lebel, M., Côté, D. C., Lévesque, L., & Ménard, C. (2024) · Glial health research. · doi:10.1016/j.ghres.2024.100004 · Cited by 4
Contrasting patterns of extrasynaptic NMDAR-GluN2B expression in macaque subgenual cingulate and dorsolateral prefrontal cortices
Joyce, M. K. P., Datta, D., Arellano, J. I., Duque, A., Morozov, Y. M., Morrison, J. H., & Arnsten, A. F. T. (2025) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2025.1553056 · Cited by 3
Gaming Disorder and Its Treatment
Griffiths, M. D., Kuss, D. J., & Pontes, H. M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.029 · Cited by 6
The Night Eating Questionnaire through the lens of the Rasch model
Aleksic, V., Milić, M., Dotlić, J., Jeremic, B., Djerkovic, B., Radić, I., Karanovic, A., Kulić, L., Galjak, M., & Gazibara, T. M. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e31929 · Cited by 3
Treatment of Alcohol, Tobacco, and Other Drug (ATOD) Misuse
Sussman, S. Y., & Bolshakova, M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.022 · Cited by 3
The Role of Culture in Addiction
Hoffman, B. R., & Unger, J. B. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.018 · Cited by 3
Sex-specific mechanisms underlie long-term potentiation at hippocampus-nucleus accumbens synapsesPreprint
Copenhaver, A. E., & LeGates, T. A. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.15.575709 · Cited by 3
PREVALENCE AND ASSOCIATION OF DEPRESSION, ANXIETY AND STRESS AMONG UNDERGRADUATE MEDICAL STUDENTS OF NEPAL
Kansakar, S., Poudel, U., Guragain, A., Paudel, P., Sharma, P., Dhungana, B., Adhikari, A., & Pokhrel, P. (2023) · Journal of Chitwan Medical College · doi:10.54530/jcmc.1418 · Cited by 2
Moving Beyond Depression: Mood Symptoms Across the Spectrum Relate to Tau Pathology in Older Women at Risk for Alzheimer's Disease
Ahmadi, N., Dratva, M. A., Heyworth, N. C., Wang, X., Blennow, K., Banks, S. J., & Sudermann, E. E. (2024) · The International Journal of Aging and Human Development · doi:10.1177/00914150241253257 · Cited by 2
The Interplay of Food Insecurity, Resilience, Stress Mindset, and Mental Distress: Insights From a Cross‐Sectional Study
Begdache, L., Al‐Amery, A., Nagorny, K., Chowdhury, U., Rosenberg, L., & Ertem, Z. (2025) · Health Science Reports · doi:10.1002/hsr2.70787 · Cited by 5
Passionate Love Addiction: An Evolutionary Survival Mechanism That Can Go Terribly Wrong
Bolshakova, M., Fisher, H. E., Aubin, H., & Sussman, S. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.026 · Cited by 2
Philosophical Issues in the Addictions
Glackin, S. N. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.007 · Cited by 2
Prevention and Treatment
(2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.020 · Cited by 2
The Minnesota Multiphasic Personality Inventory–2–Restructured Form (MMPI-2-RF) and Patient-Reported Outcomes Measurement Information System–29 (PROMIS-29) Comparison Study: Assessing for PROMIS-29 Depression and Anxiety Psychopathologic Cutoff Values Amongst Patients Undergoing Elective Complex Spine Procedures
Kenfack, Y. J., Mofor, P., Christian, Z. K., Barrie, U., Dosselman, L. J., Stewart, N., Johnson, Z. D., Dodds, J., Hall, K., Aoun, S. G., et al. (2022) · World Neurosurgery · doi:10.1016/j.wneu.2022.05.069 · Cited by 2
Sex-by-age differences in the resting-state brain connectivityPreprint
Conrin, S. D., Zhan, L., Morrissey, Z. D., Xing, M., Forbes, A. G., Maki, P. M., Milad, M. R., Ajilore, O., & Leow, A. (2018) · arXiv (Cornell University) · doi:10.48550/arxiv.1801.01577 · Cited by 2
Molecular Signatures of Early-Onset Bipolar Disorder and Schizophrenia: Transcriptomic and Machine-Learning Insights into Calcium and cAMP Signaling, Including Sex-Specific Patterns
Afjeh, S. S., Dey, S., Kiss, D., Sanches, M., Santos, F. D., Pouget, J. G., Akbarian, N., Tripathy, S., Gonçalves, V. F., & Kennedy, J. L. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262412109 · Cited by 1
Timing Matters: Leveraging Positron Emission Tomography Imaging and Hormonal Cycles for Precision Psychiatry in Female Mental Health
May, E. M., Comasco, E., Tiepolt, S., Strauß, M., Kundaković, M., Hesse, S., Sabri, O., Villringer, A., & Sacher, J. (2026) · Biological Psychiatry · doi:10.1016/j.biopsych.2026.01.021 · Cited by 1
Neuroimmune lipidome dysregulation in major depressive disorder: A meta-analysis of peripheral endocannabinoid and N-acylethanolamine signaling
Yaseen, M., Chen, W.-J., Chang, J. P., Liu, W. C., Zailani, H., Chang, H.-C., Iqbal, A. Z., Khan, A., Yang, B., Baranova, A., et al. (2026) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2026.106910 · Cited by 1
Sex-Dependent Effects of Prenatal Stress on Learned Helplessness and Anxiety-Related Behaviours in Wistar Rats
Pereira-Figueiredo, I., Sancho, C., Carro, J., López, D. E., Gómez‐Nieto, R., & Castellano, O. (2015) · Journal of Behavioral and Brain Science · doi:10.4236/jbbs.2015.57026 · Cited by 1
Prevention and Treatment of Work Addiction
Quiñones, C., & Griffiths, M. D. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.028 · Cited by 2
Concepts of Addiction
Sussman, S. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.003 · Cited by 1
Kratom ( Mitragyna speciosa )
Smith, K. E., Grundmann, O., Swogger, M. T., & Garcia‐Romeu, A. (2023) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780197618431.013.15 · Cited by 1
Impact of Sexual Cognition and Sexual Anxiety on the Mental Health of Married and Unmarried Population in India
Jaisawal, K. M., Kumari, R., & Rai, G. K. (2024) · Journal of Psychosexual Health · doi:10.1177/26318318241277939 · Cited by 1
Stability and Change in Narcissism From Adolescence to Emerging Adulthood: Findings From a Longitudinal Study of Mexican-Origin Youth
Ma, W., Beck, E. D., & Robins, R. W. (2024) · Social Psychological and Personality Science · doi:10.1177/19485506241280324 · Cited by 1
Sex-specific gene expression and weighted co-expression network analysis suggest distinct sex-specific molecular signatures in acutely suicidal MDD-patients without somatic comorbidities
Fritz, M., Holzmann, K., Castany, S., Haas, H., Montag, C., Engblom, D., Streb, J., & Dudeck, M. (2025) · Frontiers in Genetics · doi:10.3389/fgene.2025.1653768 · Cited by 1
Adolescent Drug Misuse Prevention: Challenges in School-Based Programming
Scheier, L. M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.021 · Cited by 1
Measurement, Prevention, and Treatment of Exercise Addiction
Hausenblas, H. A., Mann, D. T. Y., & Downs, D. S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.036 · Cited by 2
Gender differences in geriatric syndromes as mental illness and nervous system diseases in hospitalized Thai older patients
Suanrueang, P., Shen, Y., Lin, H., Er, T., Suen, M., & Shieh, F.-A. (2021) · Psychogeriatrics · doi:10.1111/psyg.12679 · Cited by 1
The Role of Big Data Analytics in Developing System Dynamic ModelsPreprint
Kianmehr, H., Sabounchi, N. S., & Begdache, L. (2018) · Preprints.org · doi:10.20944/preprints201811.0074.v1 · Cited by 1
Validation of the Malay Translation of Brief Core Schema Scale (BCSS-M)
Jing, R. T. H. (2019) · Biomedical Journal of Scientific & Technical Research · doi:10.26717/bjstr.2019.20.003495
Contribuição do gênero, apego e estilos de amor nos tipos de ciúme
Stravogiannis, A. L. C. (2020) · doi:10.11606/t.5.2020.tde-09032020-102957
Foreword
Compton, W. M., & Blanco, C. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.001
Novel Psychoactive Substances: A New Challenge for Prevention and Treatment
Kapitány‐Fövény, M., Corazza, O., Marrinan, S., & Demetrovics, Z. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.032
Human Laboratory Paradigms in Addictions Research
Morris, V. L., Arshad, F., Balodis, I. M., Reed, D. D., MacKillop, J. M., & Amlung, M. T. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.010
Anhedonia in Addictive Behaviors
Dyer, W. G., Leventhal, A. M., Goldenson, N. I., & Bello, M. S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.039
American Legal Issues in Addiction Treatment and Research
Willick, D. H. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.041
The Physical and Social Environments as Determinants of Health: Implications for Substance and Behavioral Addictions
Strack, R. W., Orsini, M. M., Ewald, D. R., & Scheier, L. M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.019
Developmental Coupling of Cerebral Blood Flow and fMRI Fluctuations in YouthPreprint
Baller, E. B., Valcarcel, A. M., Adebimpe, A., Alexander‐Bloch, A. F., Cui, Z., Gur, R. C., Gur, R. E., Larsen, B., Linn, K. A., O’Donnell, C. M., et al. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3966641
Clinical and Research Methods in the Addictions
Sussman, S. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.008
Levels of Analysis and Etiology
(2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.014
Ongoing and Future Research Directions
(2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.030
Preface
Sussman, S. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.002
Impaired Physicians
Srivastava, A. B., & Gold, M. S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.033
Index
Sussman, S. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.042
Sex-specific association between emotion negativity and neural processing of reward feedback in young childrenPreprint
Chung, Y. S., Bagdasarov, A., & Gaffrey, M. S. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.06.20.496831
relationship between specific psychiatric disorders and type of crimes committed in a forensic psychiatry population
de Jesús, M., Martins, V. E., Faria, I., & Quartilho, M. J. (2022) · Debates em Psiquiatria · doi:10.25118/2763-9037.2022.v12.405
X-Chromosome Dependent Differences in the Neuronal Molecular Signatures and Their Implications in Sleep Patterns
Moysés‐Oliveira, M., Favilla, B. P., Melaragno, M. I., & Tufik, S. B. (2023) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2023.06.014
Astroglial Cells as Gonadal Hormone Targets: Mediators of Sex Differences in Development and Adulthood
Rurak, G. M. (2023) · Carleton University's Institutional Repository (MacOdrum Library, Carleton University) · doi:10.22215/etd/2023-15750
Behavioral, endocrine, and neural responses to stress in postpartum and nulliparous rats : potential mechanisms of postpartum stress resilience
Medina, J. (2021) · doi:10.54014/mfr0-spyt
Sex and gender differences in co-occurring substance use and depressive disorders: a systematic review
Grant, P. E., Sorkhou, M., Ryan, J., & George, T. P. (2025) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2025.2577725
Sex-Specific Insights in Neuroscience: From Brain Structure to Mental Health Interventions
Kim, H., & Lee, H. (2026) · Springer eBooks · doi:10.1007/978-981-95-2070-1_4
Divergent behavioral strategies in Wistar and Wistar-Kyoto rats in a naturalistic task reveal mood disorder phenotypes
Ham, J. R., & McDonald, R. J. (2026) · iScience · doi:10.1016/j.isci.2026.115459
Epilepsie et psychopathologie dans deux populations vulnérables : les adultes avec déficience intellectuelle et les adultes suicidants
Akrout, B. (2022) · theses.fr (ABES) · doi:10.70675/c468b341z4e42z402dz9a54zf997695047a1
Multi-omic molecular signatures from peripheral blood samples of patients with mood disorders
Mokhtari, A. (2022) · theses.fr (ABES) · doi:10.70675/6e6b049ez0ae2z40f2za015z47c5c58102d3
Temporal trends in the prevalence of psychiatric diagnoses among aging veterans in the U.S. Department of Veterans Affairs healthcare system: An analysis by sex, age, period, and cohort
Beydoun, H. A., Beydoun, M. A., Nixdorff, N., Wallace, R. B., & Tsai, J. (2026) · Psychiatry Research · doi:10.1016/j.psychres.2026.117291
Personality disorders and related healthcare use among older United States veterans experiencing housing instability and homelessness, 2016–2024
Beydoun, H. A., Beydoun, M. A., Edwards‐Stewart, A., & Tsai, J. (2026) · GeroScience · doi:10.1007/s11357-026-02409-2
Sex-Specific Stress Outcomes Following Acute and Chronic Social Defeat StressPreprint
Stewart, E., Manganaro, A., Anderson, K., Lipshutz, A. B., Jagnarine, S., Fortuna, D., Bryan, L., Aziz, L., Rogu, P. J., Saltz, V., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.25.754264
BindingDB Entry 50045665: Exploring new selective 3-benzylquinoxaline-based MAO-A inhibitors: design, synthesis, biological evaluation and docking studies.
BindingDB (2016) · UC San Diego · doi:10.7270/q2vh5qj9
BindingDB Entry 50012399: New 2-Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors.
BindingDB (2022) · UC San Diego · doi:10.7270/q2g44v06

Authors: Seney, M. L., & Sibille, E.
Affiliations: University of Pittsburgh (US)
Centre for Addiction and Mental Health (CA)
Corresponding author: Seney, Marianne L
Sibille, Etienne
ORCID: Seney, Marianne L
Sibille, Etienne
Venue: Biology of Sex Differences
Publisher: Springer Science and Business Media LLC
Published: 2014-12
Volume: 5
Issue: 1
Pages: 17-17
ISSN: 2042-6410 (ISSN-L)
DOI: 10.1186/s13293-014-0017-3
PMC: PMC4268901
OpenAlex: W2120430663
Cited by: 181
References: 122
Citations by year: 2026: 7 · 2025: 12 · 2024: 11 · 2023: 16 · 2022: 17 · 2021: 19 · 2020: 55 · 2019: 9 · 2018: 13 · 2017: 9 · 2016: 5 · 2015: 8
FWCI: 3.51
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0 (unspecified)
Locations: Biology of Sex Differences (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
D-Scholarship@Pitt (University of Pittsburgh) (acceptedVersion)
TSpace (University of Toronto) (submittedVersion)
Funders: National Institute of Mental Health (MH084060, MH103473, MH085111, R21MH085111, K01MH103473, K02MH084060)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Keywords: mood disorders, sex differences, depression, anhedonia, cortico-limbic network, mood regulation, rodent models, mouse model of depression, translational research, sex differences in prevalence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Sex differences in mood disorders: perspectives from humans and rodent models

Abstract

Overview

Integrity signals

Figures

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks