The DOI matches its Crossref record; 91 of the 91 references it cites were found in a registry or an index.
Piezoelectric smart biomaterials for bone and cartilage tissue engineering
Open accessAbstract
Tissues like bone and cartilage are remodeled dynamically for their functional requirements by signaling pathways. The signals are controlled by the cells and extracellular matrix and transmitted through an electrical and chemical synapse. Scaffold-based tissue engineering therapies largely disturb the natural signaling pathways, due to their rigidity towards signal conduction, despite their therapeutic advantages. Thus, there is a high need of smart biomaterials, which can conveniently generate and transfer the bioelectric signals analogous to native tissues for appropriate physiological functions. Piezoelectric materials can generate electrical signals in response to the applied stress. Furthermore, they can stimulate the signaling pathways and thereby enhance the tissue regeneration at the impaired site. The piezoelectric scaffolds can act as sensitive mechanoelectrical transduction systems. Hence, it is applicable to the regions, where mechanical loads are predominant. The present review is mainly concentrated on the mechanism related to the electrical stimulation in a biological system and the different piezoelectric materials suitable for bone and cartilage tissue engineering.
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Cites
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Cited by
Costa, C. M., Cardoso, V. F., Martins, P., Correia, D. M., Gonçalves, R., Costa, P., Correia, V., Ribeiro, C., Fernandes, M. M., Martins, P. M., et al. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00196 · Cited by 498
Liu, Z., Wan, X., Wang, Z. L., & Li, L. (2021) · Advanced Materials · doi:10.1002/adma.202007429 · Cited by 478
Piezoelectric nanogenerators for personalized healthcare
Deng, W., Zhou, Y., Libanori, A., Chen, G., Yang, W., & Chen, J. (2022) · Chemical Society Reviews · doi:10.1039/d1cs00858g · Cited by 434
Recent Advances in 3D Printing of Smart Scaffolds for Bone Tissue Engineering and Regeneration
Yuan, X., Zhu, W., Yang, Z., He, N., Chen, F., Han, X., & Zhou, K. (2024) · Advanced Materials · doi:10.1002/adma.202403641 · Cited by 339
On the road to smart biomaterials for bone research: definitions, concepts, advances, and outlook
Montoya, C., Du, Y., Gianforcaro, A. L., Orrego, S., Yang, M., & Lelkes, P. I. (2021) · Bone Research · doi:10.1038/s41413-020-00131-z · Cited by 298
Metadata
- Authors
- Jacob, J., More, N., Kalia, K., & Kapusetti, G.
- Venue
- Inflammation and Regeneration
- Published
- 2018-02-27
- Volume
- 38
- Issue
- 1
- Pages
- 2-2
- ISSN
- 1346-8022 (ISSN-L)
- 1880-8190
- OpenAlex
- W2789404783
- Cited by
- 454
- References
- 91
- FWCI
- 10.29
- Type
- journal article
- Language
- en
- Open access
- gold
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