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Cited by 1,330

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Zinc oxide nanoparticles for selective destruction of tumor cells and potential for drug delivery applications

Open access
Rasmussen, John W, Martinez, Ezequiel, Louka, Panagiota, Wingett, Denise G·2010·Expert Opinion on Drug Delivery

Abstract

IMPORTANCE OF THE FIELD: Metal oxide nanoparticles, including zinc oxide, are versatile platforms for biomedical applications and therapeutic intervention. There is an urgent need to develop new classes of anticancer agents, and recent studies demonstrate that ZnO nanomaterials hold considerable promise. AREAS COVERED IN THIS REVIEW: This review analyzes the biomedical applications of metal oxide and ZnO nanomaterials under development at the experimental, preclinical and clinical levels. A discussion regarding the advantages, approaches and limitations surrounding the use of metal oxide nanoparticles for cancer applications and drug delivery is presented. The scope of this article is focused on ZnO, and other metal oxide nanomaterial systems, and their proposed mechanisms of cytotoxic action, as well as current approaches to improve their targeting and cytotoxicity against cancer cells. WHAT THE READER WILL GAIN: This review aims to give an overview of ZnO nanomaterials in biomedical applications. TAKE HOME MESSAGE: Through a better understanding of the mechanisms of action and cellular consequences resulting from nanoparticles interactions with cells, the inherent toxicity and selectivity of ZnO nanoparticles against cancer may be improved further to make them attractive new anticancer agents.

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Crossref · 10.1517/17425247.2010.502560

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Metadata

Authors
Rasmussen, J. W., Martinez, E., Louka, P., & Wingett, D. G.
Venue
Expert Opinion on Drug Delivery
Published
2010-08-18
Volume
7
Issue
9
Pages
1063-1077
ISSN
  • 1742-5247 (ISSN-L)
  • 1744-7593
OpenAlex
W2158685498
Cited by
1,330
References
6
FWCI
10.19
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Zinc oxide nanoparticles for selective destruction of tumor cells and potential for drug delivery applications. https://app.cochat.ai/papers/10.1517/17425247.2010.502560
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Rasmussen, J. W., Martinez, E., Louka, P., & Wingett, D. G. (2010). Zinc oxide nanoparticles for selective destruction of tumor cells and potential for drug delivery applications. Expert Opinion on Drug Delivery. https://doi.org/10.1517/17425247.2010.502560

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.