Multiple control of interleukin-8 gene expression

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Separately or Combined, LukG/LukH Is Functionally Unique Compared to Other Staphylococcal Bicomponent Leukotoxins

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Tip110/SART3 regulates IL-8 expression and predicts the clinical outcomes in melanoma

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Prolonged neutrophil retention in the wound impairs zebrafish heart regeneration after cryoinjury

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Induction of IL-8 expression by Cordyceps militaris grown on germinated soybeans through lipid rafts formation and signaling pathways via ERK and JNK in A549 cells

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A P2X Ion Channel–Triggered NF-κB Pathway Enhances TNF-α–Induced IL-8 Expression in Airway Epithelial Cells

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Inflammatory Regulation by TNF-α-Activated Adipose-Derived Stem Cells in the Human Bladder Cancer Microenvironment

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Quantifying persistence in the T‐cell signaling network using an optically controllable antigen receptor

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Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway

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Genetic polymorphisms of interleukin 8 and risk of ulcerative colitis in the Chinese population

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Increased Epithelial Gap Density in the Noninflamed Duodenum of Children With Inflammatory Bowel Diseases

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N-Methyl-D-Aspartate and σ-Ligands Change the Production of Interleukins 8 and 10 in Lymphocytes through Modulation of the NMDA Glutamate Receptor

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Induction of p38- and gC1qR-dependent IL-8 expression in pulmonary fibroblasts by soluble hepatitis C core protein

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p300 and C/EBPβ-regulated IKKβ expression are involved in thrombin-induced IL-8/CXCL8 expression in human lung epithelial cells

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Activation of muscarinic cholinoceptor ameliorates tumor necrosis factor‐α‐induced barrier dysfunction in intestinal epithelial cells

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Prostaglandin E 2modulates IL‐8 expression through formation of a multiprotein enhanceosome in human colonic epithelial cells

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Human neutrophil peptides induce interleukin-8 in intestinal epithelial cells through the P2 receptor and ERK1/2 signaling pathways

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Salmonella enterica Typhimurium SipA induces CXC-chemokine expression through p38MAPK and JUN pathways

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Inhibition of cell growth and induction of inflammation by endosulfan in HUVEC-C cells

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hKSR-2 inhibits MEKK3-activated MAP kinase and NF-κB pathways in inflammation

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Differential regulation of interleukin-8 gene transcription by death receptor 3 (DR3) and type I TNF receptor (TNFRI)

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THE p38 MITOGEN-ACTIVATED PROTEIN KINASE PATHWAY PLAYS A CRITICAL ROLE IN PAR2-INDUCED ENDOTHELIAL IL-8 PRODUCTION AND LEUKOCYTE ADHESION

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Amphiphilic pyridinium salts block TNFα/NFκB signaling and constitutive hypersecretion of interleukin-8 (IL-8) from cystic fibrosis lung epithelial cells

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EGR-1 and DUSP-1 are important negative regulators of pro-allergic responses in airway epithelium

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Investigating interleukin-8 in Alzheimer's disease: A comprehensive review

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Suppressing NF-κB and NKRF Pathways by Induced Pluripotent Stem Cell Therapy in Mice with Ventilator-Induced Lung Injury

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Aberrant cytokine pattern of the nasal mucosa in granulomatosis with polyangiitis

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IL-8 regulates the stemness properties of cancer stem cells in the small-cell lung cancer cell line H446

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Negative regulation of IL-8 in human astrocytes depends on β-catenin while positive regulation is mediated by TCFs/LEF/ATF2 interaction

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The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells

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Therapeutic and Metagenomic Potential of the Biomolecular Therapies against Periodontitis and the Oral Microbiome: Current Evidence and Future Perspectives

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Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect

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T oll‐Like Receptor Expression and Function in the COV 434 Granulosa Cell Line

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Transcriptional mechanisms and protein kinase signaling mediate organic dust induction of IL-8 expression in lung epithelial and THP-1 cells

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The tobacco smoke component acrolein induces glucocorticoid resistant gene expression via inhibition of histone deacetylase

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Evaluation of Glucocorticoid Receptor Function in COPD Lung Macrophages Using Beclomethasone-17-Monopropionate

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Infiltrating T Cells Promote Bladder Cancer Progression via Increasing IL1→Androgen Receptor→HIF1α→VEGFa Signals

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The intracellular pyrimidine 5′-nucleotidase NT5C3A is a negative epigenetic factor in interferon and cytokine signaling

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TRAF1 suppresses antifungal immunity through CXCL1-mediated neutrophil recruitment during Candida albicans intradermal infection

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Nucleosomes activate NF‐κB in endothelial cells for induction of the proangiogenic cytokine IL‐8

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Identification and Expression Profiles of IL-8 in Bighead Carp (Aristichthys nobilis) in Response to Microcystin-LR

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Characterisation of haematological profiles and whole blood relative gene expression levels in Holstein-Friesian and Jersey bull calves undergoing gradual weaning

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Air pollution-related metals induce differential cytokine responses in bronchial epithelial cells

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Modulation of vascular function and anti-aggregation effect induced by (1 → 3) (1 → 6)-β-d-glucan of Saccharomyces cerevisiae and its carboxymethylated derivative in rats

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Effect of interleukin (IL)-8 on benzo[a]pyrene metabolism and DNA damage in human lung epithelial cells

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7keto-stigmasterol and 7keto-cholesterol induce differential proteome changes to intestinal epitelial (Caco-2) cells

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Fluoride-induced IL-8 release in human epithelial lung cells: Relationship to EGF-receptor-, SRC- and MAP-kinase activation

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Functional characterisation of bovine interleukin 8 promoter haplotypes in vitro

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HOXC9: A Key Regulator of Endothelial Cell Quiescence and Vascular Morphogenesis

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15-Deoxy-Δ12,14-Prostaglandin J2 Inhibits IFN-Inducible Protein 10/CXC Chemokine Ligand 10 Expression in Human Microglia: Mechanisms and Implications

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Beyond the hype: a comprehensive exploration of CBD’s biological impacts and mechanisms of action

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The role of PKC in CXCL8 and CXCL10 directed prostate, breast and leukemic cancer cell migration

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Recombinant Human Trefoil Factor 3 Ameliorates Bowel Injury: Its Anti-Inflammatory Effect on Experimental Necrotizing Enterocolitis

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Synergistic Effect of Tumor Necrosis Factor-Alpha and Hydrogen Peroxide on the Induction of IL-8 Production in Human Intestinal Caco-2 Cells

Shin, H. S., Zhao, Z., Satsu, H., Totsuka, M., & Shimizu, M. (2010) · Inflammation · doi:10.1007/s10753-010-9251-y · Cited by 20

Anti-inflammatory effects of garenoxacin on IL-8 production and ERK1/2 activation induced by lipopolysaccharides in A549 and THP-1 cells

Hara, S., Ishimatsu, Y., Mukae, H., Sakamoto, N., Kakugawa, T., Fujita, H., Hara, A., & Kohno, S. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.06.046 · Cited by 20

Gene Expression Profiling of Human Vaginal Cells In Vitro Discriminates Compounds with Pro-Inflammatory and Mucosa-Altering Properties: Novel Biomarkers for Preclinical Testing of HIV Microbicide Candidates

Zalenskaya, I. A., Joseph, T. D., Bavarva, J. H., Yousefieh, N., Jackson, S. S., Fashemi, T., Yamamoto, H. S., Settlage, R. E., Fichorova, R. N., & Doncel, G. F. (2015) · PLoS ONE · doi:10.1371/journal.pone.0128557 · Cited by 21

Hemoglobin Receptor Protein from Porphyromonas gingivalis Induces Interleukin-8 Production in Human Gingival Epithelial Cells through Stimulation of the Mitogen-Activated Protein Kinase and NF-κB Signal Transduction Pathways

Fujita, Y., Nakayama, M., Naito, M., Yamachika, E., Inoue, T., Nakayama, K., Iida, S., & Ohara, N. (2013) · Infection and Immunity · doi:10.1128/iai.01140-12 · Cited by 20

New use for an old drug: COX‐independent anti‐inflammatory effects of sulindac in models of cystic fibrosis

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Effect of vitamin D3 on the immunomodulation of head kidney after Edwardsiella ictaluri challenge in yellow catfish (Pelteobagrus fulvidraco)

Cheng, K., Tang, Q., Huang, Y., Liu, X., Karrow, N. A., & Wang, C. (2020) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2020.02.023 · Cited by 20

Isoeugenol destabilizes IL-8 mRNA expression in THP-1 cells through induction of the negative regulator of mRNA stability tristetraprolin

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Activation of MAPK participates in low shear stress-induced IL-8 gene expression in endothelial cells

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Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells

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Bleomycin induces IL-8 and ICAM-1 expression in microvascular pulmonary endothelial cells

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Listeria monocytogenes induced Rac1-dependent signal transduction in endothelial cells

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Engulfment of apoptotic cells expressing HCV proteins leads to differential chemokine expression and STAT signaling in human dendritic cells

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Vigilant Keratinocytes Trigger Pathogen-Associated Molecular Pattern Signaling in Response to Streptococcal M1 Protein

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Splicing factor proline/glutamine-rich is a novel autoantigen of dermatomyositis and associated with anti-melanoma differentiation-associated gene 5 antibody

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BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer

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P38 MAPK, NF-κB, and JAK-STAT3 Signaling Pathways Involved in Capecitabine-Induced Hand-Foot Syndrome via Interleukin 6 or Interleukin 8 Abnormal Expression

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Canonical NF-κB p65, but Not p105, Contributes to IL-1β-Induced IL-8 Expression in Cardiac Fibroblasts

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Comparative effects of dietary methionine and cysteine supplementation on redox status and intestinal integrity in immunologically challenged-weaned pigs

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Effect of interleukin-17 on the expression of chemokines in gingival epithelial cells

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Expression of human papillomavirus type 16 E7 is sufficient to significantly increase expression of angiogenic factors but is not sufficient to induce endothelial cell migration

Walker, J. L., Smiley, L. C., Ingram, D. A., & Roman, A. (2010) · Virology · doi:10.1016/j.virol.2010.11.010 · Cited by 20

Cigarette smoke enhances human rhinovirus-induced CXCL8 production via HuR-mediated mRNA stabilization in human airway epithelial cells

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Modulation of NF-κB and Nrf2 control of inflammatory responses in FHs 74 Int cell line is tocopherol isoform-specific

Elisia, I., & Kitts, D. D. (2013) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00269.2013 · Cited by 19

CXCL8 is associated with the recurrence of patients with acute myeloid leukemia and cell proliferation in leukemia cell lines

Li, Y., Cheng, J., Li, Y., Jiang, Y., Ma, J., Li, Q., & Pang, T. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.03.181 · Cited by 19

Effects of a MAPK p38 inhibitor on lung function and airway inflammation in equine recurrent airway obstruction

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TRAF2 and RIPK1 redundantly mediate classical NFκB signaling by TNFR1 and CD95-type death receptors

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The CXCL8/MAPK/hnRNP-K axis enables susceptibility to infection by EV-D68, rhinovirus, and influenza virus in vitro

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Microfluidic Systems to Study Neutrophil Forward and Reverse Migration

Babatunde, K. A., Ayuso, J. M., Kerr, S. C., Huttenlocher, A., & Beebe, D. J. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.781535 · Cited by 16

Rebamipide inhibits tumor necrosis factor-α-induced interleukin-8 expression by suppressing the NF-κB signal pathway in human umbilical vein endothelial cells

Choe, J., Park, K.-Y., Lee, S., Park, S., & Kim, S. (2010) · Inflammation Research · doi:10.1007/s00011-010-0221-5 · Cited by 18

Nicotine‐Mediated Ca2+‐Influx Induces IL‐8 Secretion in Oral Squamous Cell Carcinoma Cell

Tsunoda, K., Tsujino, I., Koshi, R., Sugano, N., Sato, S., & Asano, M. (2015) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25387 · Cited by 18

A fucose specific lectin fromAspergillus flavusinduced interleukin-8 expression is mediated by mitogen activated protein kinase p38

Ghufran, M. S., Ghosh, K. K., & Kanade, S. R. (2016) · Medical Mycology · doi:10.1093/mmy/myw066 · Cited by 18

Addressing the effects of Salmonella internalization in host cell signaling on a reverse‐phase protein array

Molero, C., Rodríguez‐Escudero, I., Alemán, A., Rotger, R., Molina, M., & Cid, V. J. (2009) · PROTEOMICS · doi:10.1002/pmic.200800907 · Cited by 18

Exercise-induced up-regulation of MMP-1 and IL-8 genes in endurance horses

Cappelli, K., Felicetti, M., Capomaccio, S., Pieramati, C., Silvestrelli, M., & Supplizi, A. V. (2009) · BMC Physiology · doi:10.1186/1472-6793-9-12 · Cited by 18

Pro-inflammatory response and adverse drug reactions: Mechanisms of action of ximelagatran on chemokine and cytokine activation in a monocyte in vitro model

Edling, Y., Sivertsson, L., Andersson, T. B., Porsmyr‐Palmertz, M., & Ingelman‐Sundberg, M. (2008) · Toxicology in Vitro · doi:10.1016/j.tiv.2008.06.011 · Cited by 18

TIARP attenuates autoantibody-mediated arthritis via the suppression of neutrophil migration by reducing CXCL2/CXCR2 and IL-6 expression

Inoue, A., Matsumoto, I., Tanaka, Y., Umeda, N., Takai, C., Kawaguchi, H., Ebe, H., Yoshida, H., Matsumoto, Y., Segawa, S., et al. (2016) · Scientific Reports · doi:10.1038/srep38684 · Cited by 18

Long term metabolic arrest and recovery of HEK293 spheroids involves NF‐κB signaling and sustained JNK activation

Jack, G. D., Mead, E. A., Garst, J. F., Cabrera, M. C., DeSantis, A. M., Slaughter, S. M., Jervis, J., Brooks, A. I., Potts, M., & Helm, R. F. (2005) · Journal of Cellular Physiology · doi:10.1002/jcp.20499 · Cited by 18

Differential role for phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate-stimulated MAPK activation, Cox-2 and IL-8 expression

Grab, L. T., Kearns, M. W., Morris, A. J., & Daniel, L. W. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2003.12.002 · Cited by 18

Motorcycle Exhaust Particles Induce IL-8 Production Through NF-κB Activation in Human Airway Epithelial Cells

Lee, C., Cheng, Y., & Kang, J. (2005) · Journal of Toxicology and Environmental Health · doi:10.1080/15287390590967496 · Cited by 18

Lipopolysaccharide Exposure Modifies High Tidal Volume Ventilation-Induced Proinflammatory Mediator Expression in Newborn Rat Lungs

Roth‐Kleiner, M., Ridsdale, R. A., Cao, L., Kuliszewski, M. J., Tseu, I., McKerlie, C., & Post, M. (2007) · Pediatric Research · doi:10.1203/01.pdr.0000252437.51779.21 · Cited by 18

Molecular Biomarkers for Timely and Personalized Prediction of Maternal-Fetal Health Risk

Estrela, D., Santos, R. F., Masserdotti, A., Silini, A. R., Parolini, O., Pinto, I. M., & Cruz, A. (2025) · Biomolecules · doi:10.3390/biom15030312 · Cited by 20

Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases

Xiong, Y., Murphy, M., Manavalan, T. T., Pattabiraman, G., Qiu, F., Chang, H., Ho, I., & Medvedev, A. E. (2015) · Journal of Innate Immunity · doi:10.1159/000440838 · Cited by 17

Reversible disruption of XPO1-mediated nuclear export inhibits respiratory syncytial virus (RSV) replication

Mathew, C., Tamir, S., Tripp, R. A., & Ghildyal, R. (2021) · Scientific Reports · doi:10.1038/s41598-021-98767-2 · Cited by 17

Cancer anorexia‐cachexia syndrome is characterized by more than one inflammatory pathway

Gagnon, B., Murphy, J., Simonyan, D., Penafuerte, C., Sirois, J., Chasen, M. R., & Tremblay, M. L. (2024) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13430 · Cited by 17

TNF-α-induced CXCL8 production by A549 cells: Involvement of the non-neuronal cholinergic system

Xu, Z., Devillier, P., Xu, G.-N., Qi, H. Y., Zhu, L., Zhou, W., Hou, L.-N., Tang, Y., Yang, K., Yu, Z., et al. (2012) · Pharmacological Research · doi:10.1016/j.phrs.2012.10.016 · Cited by 17

Toll like receptor-3 priming alters diesel exhaust particle-induced cytokine responses in human bronchial epithelial cells

Bach, N. S., Låg, M., & Øvrevik, J. (2014) · Toxicology Letters · doi:10.1016/j.toxlet.2014.03.021 · Cited by 17

The biological, biochemical, and molecular profile of leukocyte chemotactic and activating cytokine, interleukin-8

Harada, A., Mukaida, N., & Matsushima, K. (1997) · Growth factors and cytokines in health and disease · doi:10.1016/s1874-5687(97)80028-6 · Cited by 2

Molecular mechanism of interleukin-8 gene expression

Mukaida, N., Okamoto, S., Ishikawa, Y., & Matsushima, K. (1994) · Journal of Leukocyte Biology · doi:10.1002/jlb.56.5.554 · Cited by 452

Regulation of Interleukin-8 Gene Expression

Roebuck, K. A. (1999) · Journal of Interferon & Cytokine Research · doi:10.1089/107999099313866 · Cited by 414

Molecular mechanisms of interleukin-8 gene expression

Mukaida, N., Okamoto, S.-I., Ishikawa, Y., & Matsushima, K. (1994)

Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways

Holtmann, H., Winzen, R., Holland, P. M., Eickemeier, S., Hoffmann, E., Wallach, D., Malinin, N. L., Cooper, J. A., Resch, K., & Kracht, M. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.10.6742 · Cited by 294