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Cited by 801

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors

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Thase, Michael E., Entsuah, A. Richard, Rudolph, Richard L.·2001·British Journal of Psychiatry
DOI 10.1192/bjp.178.3.234
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Abstract

Background: It had been suggested that the antidepressant venlafaxine, which inhibits reuptake of both serotonin and (at higher doses) noradrenaline, may result in better outcomes than treatment with selective serotonin reuptake inhibitors (SSRIs). Aims: To compare remission rates during treatment with SSRIs or venlafaxine. Method: Data from eight comparable randomised, double-blind studies of major depressive disorder were pooled to compare remission rates (Hamilton Rating Scale for Depression score ≤ 7) during treatment with venlafaxine (n=851), SSRIs (fluoxetine, paroxetine, fluvoxamine;n=748) or placebo (four studies;n=446). Results: Remission rates were: venlafaxine, 45% (382/851); SSRIs, 35% (260/748); placebo, 25% (110/446) (P< 0.001; odds ratio for remission is 1.50 (1.3–1.9), favouring venlafaxine v.SSRIs). The difference between venlafaxine and the SSRIs was significant at week 2, whereas the difference between SSRIs and placebo reached significance at week 4. Results were not dependent on any one study or the definition of remission. Conclusions: Remission rates were significantly higher with venlafaxine than with an SSRI.

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Metadata

Authors
Thase, M. E., Entsuah, A. R., & Rudolph, R. L.
Venue
British Journal of Psychiatry
Publisher
Royal College of Psychiatrists
Published
2001-03
Volume
178
Issue
3
Pages
234-241
ISSN
  • 0007-1250 (ISSN-L)
  • 1472-1465
DOI
10.1192/bjp.178.3.234
OpenAlex
W2099564543
Cited by
801
References
13
FWCI
35.74
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. https://app.cochat.ai/papers/10.1192/bjp.178.3.234
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Thase, M. E., Entsuah, A. R., & Rudolph, R. L. (2001). Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. British Journal of Psychiatry. https://doi.org/10.1192/bjp.178.3.234

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.