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Hospital Anxiety and Depression (HAD) scale: Factor structure, item analyses and internal consistency in a large population
Open accessAbstract
Background: The Hospital Anxiety and Depression (HAD) rating scale is a commonly used questionnaire. Former studies have given inconsistent results as to the psychometric properties of the HAD scale. Aims: To examine the psychometric properties of the HAD scale in a large population. Method: All inhabitants aged 20–89 years (n=92 100) were invited to take part in The Nord-Tr⊘ndelag Health Study, Norway. A total of 65 648 subjects participated, and only completed HAD scale forms (n=51 930) formed the basis for the psychometric examinations. Results: Principal component analysis extracted two factors in the HAD scale that accounted for 57% of the variance. The anxiety and depression sub-scales shared 30% of the variance. Both sub-scales were found to be internally consistent, with values of Cronbach's coefficient (a) being 0.80 and 0.76, respectively. Conclusions: Based on data from a large population, the basic psychometric properties of the HAD scale as a self-rating instrument should be considered as quite good in terms of factor structure, intercorrelation, homogeneity and internal consistency.
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“Also, it demonstrated good factor structure, intercorrelation, homogeneity and internal consistency.28”
From Protocol for a feasibility and acceptability study using a brief ACT-based intervention for people from Southwest Wales who live with persistent pain (2018) · cites this paper as [28]
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“The HADS is a validated (Bjelland, Dahl, Haug, & Neckelmann, 2002; Mykletun, Stordal, & Dahl, 2001), 14-item measure of anxiety and depression.”
From A pilot case series of a brief acceptance and commitment therapy (ACT)-based guided self-help intervention for improving quality of life and mood in muscle disorders (2017) · cites this paper as Mykletun, Stordal, & Dahl, 2001
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“Therefore, the Hospital Anxiety and Depression Scale (HADS) seems more appropriate to use: this instrument has shown solid psychometric properties regarding factor analysis and internal consistency.”
From The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries (2015) · cites this paper as Mykletun et al., 2001
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“However, the psychometric approach to evaluate depression used a self-administrated scale with strong psychometric properties.”
From The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries (2015) · cites this paper as Mykletun et al., 2001
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Measurement invariance of the depressive symptoms scale during adolescence
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“…in terms of factor structure, intercorrelation, homogeneity, and internal consistency 30 and has been found to perform well in assessing symptom severity and caseness of anxiety and depression, 31 although use of the HADS as a reliable measure of depression has also been questioned by some authors.”
Loneliness as a risk factor for metabolic syndrome: results from the HUNT study
Henriksen, R. E., Nilsen, R. M., & Strandberg, R. B. (2019) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2019-212335 · Cited by 42
Nitrous oxide-oxygen or oral midazolam for pediatric outpatient sedation
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Comorbid Mental Disorders in Laryngectomees
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Sense of coherence, burden, and affective symptoms in family carers of people with dementia
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Comparação dos níveis de ansiedade e depressão entre idosos ativos e sedentários
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“At the end of each 3-month period, elevated levels of depression and/or anxiety (i.e. ≥16 on the CES-D and/or ≥8 on the HADS-A) induced moving on to the following step of the intervention.”
MethodInfluentialActivity of daily living problems in older cancer survivors: a population-based controlled study
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“All participants in HUNT-2 provided written consent.”
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“The HADS has shown good internal consistency [35, 36].”
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“HADS prevents the reference to somatic symptoms and is widely used to assess anxiety and depression among non-psychiatric, hospital outpatients, and well validated in several clinical situations [3, 28, 29].”
BackgroundSun, Y., Zhang, D., Yang, Y., Wu, M., Xie, H., Zhang, J., Jia, J., & Su, Y. (2016) · Archives of Psychiatric Nursing · doi:10.1016/j.apnu.2016.09.015 · Cited by 37
Metacognitions Across the Continuum of Smoking Dependence
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Psychological symptoms in children of parents with chronic pain—the HUNT study
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“The measure has shown to have good case-finding properties for anxiety and depression, as defined by the DSM-IV [4,16,26].”
MethodGynecologic oncology patients' satisfaction and symptom severity during palliative chemotherapy
von Gruenigen, V. E., Hutchins, J., Reidy, A. M., Gibbons, H. E., Daly, B. J., Eldermire, E., & Fusco, N. L. (2006) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-4-84 · Cited by 37
Autonomic and subjective responsivity to emotional images in people with dissociative seizures
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“The psychometric properties of the Norwegian translation of HADS were found to be excellent in the HUNT 2 [14].”
MethodInsomnia and Endothelial Function – The HUNT 3 Fitness Study
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“The psychometric properties of the scale have been validated previously in the HUNT study [22].”
MethodSampogna, F., ABENI, D. D., Gieler, U., Tomas-Aragones, L., Lien, L., Poot, F., Jemec, G. B. E., Szabó, C., Linder, D., van Middendorp, H., et al. (2020) · Acta Dermato Venereologica · doi:10.2340/00015555-3477 · Cited by 36
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Metal Music and Mental Health in France
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“It is short and rapid in administration (taking 2–5 min) and generally wellaccepted (Mykletun et al., 2001).”
BackgroundCharacteristics of anxiety and psychological well-being in chronic post-stroke patients.
D'Aniello, G. E., Scarpina, F., Mauro, A., Mori, I., Castelnuovo, G., Bigoni, M., Baudo, S., & Molinari, E. (2014) · Journal of Neurological Sciences · doi:10.1016/j.jns.2014.01.005 · Cited by 38
“Depression and anxiety were measured using the Italian version of the Hospital Anxiety and Depression Scale (HAD Scale) [32] which is a commonly used questionnaire assessing psychiatric morbidity [33] and mood disorders [34] in post-stroke patients by relying on the feelings from the previous week.”
MethodGalé, C. R., Allerhand, M., Sayer, A. A., Cooper, C. C., Dennison, E. M., Starr, J. M., Ben‐Shlomo, Y., Gallacher, J., Kuh, D. J., & Deary, I. J. (2010) · International Psychogeriatrics · doi:10.1017/s1041610210000256 · Cited by 40
“Comparison of factor structures in both the Dutch (Spinhoven et al., 1997) and the Norwegian samples (Mykletun et al., 2001) found no indication that these differed between age groups, but in a study using the English version of the scale in general population samples, relative loadings of symptoms…”
InfluentialPost-traumatic growth and value-directed living after acquired brain injury
Baseotto, M. C., Morris, P. G., Gillespie, D. C., & Trevethan, C. T. (2022) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2020.1798254 · Cited by 34
“80) subscales (Mykletun et al., 2001), and for a combined overall “distress” score (α = .”
BackgroundBratås, O., Ga, E., Rannestad, T., & Walstad, R. A. (2010) · Chronic Respiratory Disease · doi:10.1177/1479972310374343 · Cited by 34
Knowles, S. R., Tribbick, D., Connell, W. R., Castle, D. J., Salzberg, M. R., & Kamm, M. A. (2014) · Journal of Wound Ostomy and Continence Nursing · doi:10.1097/won.0000000000000073 · Cited by 34
Saltnes, S. S., Jensen, J. L., Sæves, R., Nordgarden, H., & Geirdal, A. Ø. (2017) · Acta Odontologica Scandinavica · doi:10.1080/00016357.2017.1357189 · Cited by 36
“The psychometric properties of the Norwegian version of HADS have been demonstrated to be excellent [17].”
MethodLeahy, F., Ridout, N., Mushtaq, F., & Holland, C. (2017) · Aging Neuropsychology and Cognition · doi:10.1080/13825585.2017.1365815 · Cited by 35
“In a large population study, Mykletun, Stordal, and Dahl (2001) reported Cronbach’s alpha of 0.76 for depression and 0.8 for anxiety.”
BackgroundInfluentialReproductive outcomes among dental personnel: a review of selected exposures.
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Psychosocial consequences of skin cancer screening
Risica, P. M., Matthews, N. H., Dionne, L. A., Mello, J., Ferris, L. K., Saul, M. I., Geller, A. C., Solano, F. X., Kirkwood, J. M., & Weinstock, M. A. (2018) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2018.04.011 · Cited by 34
“com/educationalresources) has been previously shown to improve PCP skills related to melanoma detection, including the ability to appropriately reassure patients who have benign lesions that may resemble melanoma, such as seborrheic keratoses (Mykletun et al., 2001; Singer et al., 2009).”
BackgroundMethodDres, M. (2011) · Revue des Maladies Respiratoires Actualités · doi:10.1016/s1877-1203(11)70038-6 · Cited by 33
The Fear of Others: A Pilot Study of Social Anxiety Processes in Paranoia
Newman‐Taylor, K., & Stopa, L. (2012) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465812000690 · Cited by 38
Lu, W. Y.-R., Krellman, J. W., & Dijkers, M. P. J. M. (2016) · Neurorehabilitation · doi:10.3233/nre-151296 · Cited by 39
Explicit Facial Emotion Processing in Patients With Dissociative Seizures
Pick, S., Mellers, J. D. C., & Goldstein, L. H. (2016) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000327 · Cited by 33
“This reliable and valid scale (39,42) was developed for use in general medical settings, measuring current (nonsomatic) symptoms of anxiety and depression over the previous week.”
BackgroundCaregiver Choice and Caregiver Outcomes: A Longitudinal Study of Irish Spousal Dementia Caregivers
Pertl, M. M., Sooknarine-Rajpatty, A., Brennan, S., Robertson, I. H., & Lawlor, B. A. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.01801 · Cited by 33
McDonald, J. S., & Rapkin, A. J. (2012) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2012.02909.x · Cited by 33
Straat, J. H., van der Ark, L. A., & Sijtsma, K. (2013) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2012.11.012 · Cited by 33
“Exploratory factor analysis [14,17] yielded a 2-factor solution in which all items with index A loaded on the Anxiety factor and all items with index D loaded on the Depression factor.”
MethodLindberg, M. F., Miaskowski, C. A., Rustøen, T., Rosseland, L. A., Paul, S. M., Cooper, B. A., & Lerdal, A. (2016) · Pain Medicine · doi:10.1093/pm/pnw080 · Cited by 33
Assessing the Chinese version of Pittsburgh Sleep Quality Index in non-clinical adolescents
Guo, C. (2022) · Current Psychology · doi:10.1007/s12144-022-03581-2 · Cited by 34
Algladi, T., HARRIS, M. L., Whorwell, P. J., Paine, P., & Hamdy, S. (2015) · Pain · doi:10.1097/j.pain.0000000000000187 · Cited by 32
“Healthy volunteers and patients with IBS were asked to complete the Hospital Anxiety and Depression (HAD) rating scale.(37) In addition, patients with IBS were asked to complete the IBS Symptom Severity Score.”
MethodSarmanova, A., Fernandes, G., Richardson, H., Valdes, A. M., Walsh, D. A., Zhang, W., & Doherty, M. (2018) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2018.07.013 · Cited by 32
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An exploration of the psychologic impact of contact isolation on patients in Singapore
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Rimehaug, T., & Wallander, J. L. (2009) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-009-0110-9 · Cited by 32
“The validity of HADS has been satisfactory in numerous analyses [6, 18, 31].”
BackgroundKlokk, M., Götestam, K. G., & Mykletun, A. (2010) · BMC Dermatology · doi:10.1186/1471-5945-10-3 · Cited by 32
“In accordance with the findings on anxiety disorders and depression in the National Comorbidity Survey [29], the HADS components of anxiety and depression shares 30% variance [30].”
ResultSelf-citationIsaksen, K., Munk, P. S., Giske, R., & Larsen, A. I. (2016) · Journal of Rehabilitation Medicine · doi:10.2340/16501977-2043 · Cited by 36
Andenæs, R., Momyr, A., & Brekke, I. (2018) · BMC Public Health · doi:10.1186/s12889-018-5094-5 · Cited by 31
“Previous studies and reviews have concluded that the HADS is a reliable and valid instrument for assessing the separate dimensions and symptom severity of anxiety and depression in somatic, psychiatric, and primary care patients, as well as in the general population [28].”
BackgroundHolten, K. I. A., Bernklev, T., Opheim, R., Johansen, I., Olsen, B. C., Lund, C. I., Strande, V., Medhus, A. W., Perminow, G., Bengtson, M., et al. (2023) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjad094 · Cited by 33
“22 The HADS has been translated into Norwegian and validated, 25 and consists of 14 items divided into two-dimensional subscales, HADS-D and HADS-A, with seven items each.”
MethodCaregivers’ experience of risk in dementia: The LASER-AD Study
Walker, A. E., Livingston, G., Cooper, C., Katona, C., & Kitchen, G. (2006) · Aging & Mental Health · doi:10.1080/13607860600637828 · Cited by 31
“This scale has been validated throughout the age range and in all settings including the community to identify clinically significant anxiety and depression (Mykletun, Stordal, & Dahl, 2001 ; Bjelland, Dahl, Haug, & Neckelmann, 2002 ).”
MethodPetraškienė, R., Valiukevičienė, S., & Macijauskienė, J. (2016) · Medicina · doi:10.1016/j.medici.2016.07.001 · Cited by 31
“This scale is used for surveys of patients treated in general and specialized non-mental healthcare institutions [26].”
Nøst, T. H., Steinsbekk, A., Bratås, O., & Grønning, K. (2018) · BMC Health Services Research · doi:10.1186/s12913-018-3843-x · Cited by 35
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The Treatment of Anxiety in Young Children: Results of an Open Trial of the Fun FRIENDS Program
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“In addition, scores on the Hospital Anxiety and Depression Scale (HADS), seen in Table 3, showed a significant (p 0.01) reduction in both anxiety and depression during the rehabilitation period.”
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The effect of attachment orientation priming on pain sensitivity in pain-free individuals
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Factors Associated With Presenteeism and Psychological Distress Using a Theory-Driven Approach
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Watchful waiting for subthreshold depression and anxiety in visually impaired older adults
van der Aa, H. P. A., Bruin, E. K.-D., van Rens, G. H. M. B., Twisk, J. W. R., & van Nispen, R. M. A. (2015) · Quality of Life Research · doi:10.1007/s11136-015-1032-5 · Cited by 31
“The HADS-A is a 7-item subscale which specifically targets anxiety, with scores ranging from 0 to 21 and a cut-off score for subthreshold anxiety of C8 [34].”
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“Also, it demonstrated good factor structure, intercorrelation, homogeneity and internal consistency.(28) This scale has been routinely used in research involving patients with persistent pain.”
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Co-morbid depression and chronic illness related to coping and physical and mental health status
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“In addition, patients completed the HADS, which has excellent psychometric properties in specialist and primary care populations [35,36].”
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“‘Integration’; ‘mixed picture in which integration predominates’; ‘mixed picture in which sealingover predominates’ and ‘sealing-over’(49)]; Insight Scale reliably assesses changes in levels of insight in terms of perceived need for treatment (50); HADS a 14-item self-report measure found to reliably assess anxiety an…”
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Anxiety and Depression in Patients with Intracranial Arachnoid Cysts–A Prospective Study
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“83) (Mykletun et al., 2001; Bjelland et al., 2002; Michopoulos et al., 2008).”
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“In both scales, a score of 0-7 indicates the absence of anxiety or depression, a score of 8-10 indicates possible anxiety or depression, and a score of 11 or higher indicates presence of anxiety or depression [10], [11].”
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“…populations were analysed in the UK and abroad, from the Netherlands (Andrea et al. 2004), Germany (Barth & Martin 2005), France (Friedman et al. 2001), Greece (Michopoulos et al. 2008), Norway (Mykletun et al. 2001), Portugal (Pais-Ribeiro et al. 2007) and Spain (Quintana et al. 2003).”
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“[15], reported a Cronbach’s alpha coefficient of 0.”
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“70 (39) indicate a good internal reliability.”
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Metadata
- Authors
- Mykletun, A., Stordal, E., & Dahl, A. A.
- Affiliations
- University of Bergen (NO)
- University of Oslo (NO)
- Corresponding author
- Mykletun, Arnstein
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2001-12
- Volume
- 179
- Issue
- 6
- Pages
- 540-544
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2106572906
- Cited by
- 908
- References
- 23
- Citations by year
- 2026: 16 · 2025: 28 · 2024: 33 · 2023: 31 · 2022: 39 · 2021: 31 · 2020: 28 · 2019: 31 · 2018: 36 · 2017: 38 · 2016: 48 · 2015: 60 · 2014: 58 · 2013: 61 · 2012: 56
- FWCI
- 21.49
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Norges Teknisk-Naturvitenskapelige Universitet
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
- Health Sciences › Nursing › Research and Theory › Health Education and Validation
- Keywords
- Hospital Anxiety and Depression Scale, psychometric properties, factor structure, internal consistency, anxiety, depression, self-report questionnaire, Nord-Trøndelag Health Study, item analysis
- MeSH terms
- Adult, Aged, Aged, 80 and over, Anxiety Disorders, Mental Disorders, Depressive Disorder, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Psychometrics, Reproducibility of Results
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