Cost-effectiveness of current and optimal treatment for schizophrenia
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Background: This paper is part of a project to identify the proportion of the burden of each mental disorder averted by current and optimal interventions, and the cost-effectiveness of both. Aims: To use epidemiological data on schizophrenia to model the cost-effectiveness of current and optimal treatment. Method: Calculate the burden of schizophrenia in the years lived with disability (YLD) component of disability-adjusted life-years lost, the proportion averted by current interventions, the proportion that could be averted by optimal treatment and the cost-effectiveness of both. Results: Current interventions avert some 13% of the burden, whereas 22% could be averted by optimal treatment. Current interventions cost about AUS$200 000 per YLD averted, whereas optimal treatment at a similar cost could increase the number of YLDs averted by two-thirds. Even so, the majority of the burden of schizophrenia remains unavertable. Conclusions: Optimal treatment is affordable within the present budget and should be implemented.
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Many people with schizophrenia have persisting symptoms, despite the best mix of interventions we can offer.
“Many people with schizophrenia have persisting symptoms, despite the best mix of interventions we can offer.”
From A Systematic Review of the Prevalence of Schizophrenia (2005) · cites this paper as [239]
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“The case I wish to prosecute relates to the deeper issue of how we can address the unavoidable burden of disability associated with schizophrenia (Andrews et al., 2003).”
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“Yet, in Australia, the risk of treatments impacting adversely on labor force activity is increased by the fact that universal health care and welfare systems [20, 21 ] are typically segregated from the available forms of public funded disability employment and occupational rehabilitation services.”
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Cannabis: A Clue or a Distraction in the Search for ‘Causes’ of Psychosis?
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“Even our best treatments are suboptimal ( Andrews et al. 2003, 2004 ).”
Background
- Authors
- Andrews, G., Sanderson, K., Corry, J., Issakidis, C., & Lapsley, H.
- Affiliations
- UNSW Sydney (AU)
- Corresponding author
- Andrews, Gavin
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2003-11
- Volume
- 183
- Issue
- 5
- Pages
- 427-435
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2171184241
- Cited by
- 83
- References
- 42
- Citations by year
- 2026: 1 · 2025: 2 · 2023: 1 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 5 · 2017: 2 · 2016: 2 · 2015: 2 · 2014: 2 · 2013: 4 · 2012: 4
- FWCI
- 5.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- eCite Digital Repository (University of Tasmania) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- UEA Digital Repository (University of East Anglia) (submittedVersion)
- Funders
- Medical Research Council
- National Health and Medical Research Council (113807)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- schizophrenia, cost-effectiveness, optimal treatment, disability-adjusted life years, years lived with disability, disease burden, mental illness, treatment affordability
- MeSH terms
- Aged, Cost-Benefit Analysis, Financing, Organized, Humans, Mental Health Services, Psychotherapy, Schizophrenia, Prevalence, Treatment Outcome, Cost of Illness, Quality-Adjusted Life Years, Evidence-Based Medicine
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