The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Neurocognitive impairment in euthymic patients with bipolar affective disorder
Open accessAbstract
Background: Persistent impairments in neurocognitive function have been described in patients with bipolar disorder whose disease is in remission. However, methodological issues such as the effect of residual mood symptoms and hypercortisolaemia may confound such studies. Aims: To assess neurocognitive functioning in prospectively verified euthymic patients with bipolar disorder. Method: Sixty-three patients with bipolar disorder and a matched control group completed a comprehensive neurocognitive test battery. Euthymia was confirmed in the patient group by prospective clinical ratings over 1 month prior to testing. Saliva samples were collected to profile basal cortisol secretion. Results: Patients were significantly impaired across a broad range of cognitive domains. Across the domains tested, clinically significant impairment was observed in 3% to 42% of patients. Deficits were not causally associated with residual mood symptoms or hypercortisolaemia. Conclusions: Neurocognitive impairment persists in patients whose bipolar disorder is in remission. This may represent a trait abnormality and be a marker of underlying neurobiological dysfunction.
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Cites
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Self-citationImpaired Neuropsychological Performance in Euthymic Patients With Recurring Mood Disorders
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Different trait markers for schizophrenia and bipolar disorder: a neurocognitive approach
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Cited by
A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder
Robinson, L. J., Thompson, J. M., Gallagher, P., Goswami, U., Young, A. H., Ferrier, I. N., & Moore, P. B. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.02.016 · Cited by 962
Self-citationKurtz, M. M., & Gerraty, R. T. (2009) · Neuropsychology · doi:10.1037/a0016277 · Cited by 433
The HPA axis in bipolar disorder: Systematic review and meta-analysis
Belvederi Murri, M., Prestia, D., Mondelli, V., Pariante, C., Patti, S., Olivieri, B., Arzani, C., Masotti, M., Respino, M., Antonioli, M., et al. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.10.014 · Cited by 391
Knorr, U., Vinberg, M., Kessing, L. V., & Wetterslev, J. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.04.001 · Cited by 317
Neurocognitive impairment in bipolar disorder patients: functional implications
Wingo, A. P., Harvey, P. D., & Baldessarini, R. J. (2009) · Bipolar Disorders · doi:10.1111/j.1399-5618.2009.00665.x · Cited by 274
Metadata
- Authors
- Thompson, J. M., Gallagher, P., Hughes, J. H., Watson, S., Gray, J. M., Ferrier, I. N., & Young, A. H.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2005-01
- Volume
- 186
- Issue
- 1
- Pages
- 32-40
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2086340288
- Cited by
- 432
- References
- 8
- FWCI
- 17.78
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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