The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Comorbid substance use and age at onset of schizophrenia
Open accessAbstract
Background: Substance use may be a risk factor for the onset of schizophrenia. Aims: To examine the association between substance use and age at onset in a UK, inner-city sample of people with recent-onset schizophrenia. Method: The study sample consisted of 152 people recruited to the West London First-Episode Schizophrenia Study. Self-reported data on drug and alcohol use, as well as information on age at onset of psychosis, were collected. Mental state, cognition (IQ, memory and executive function) and social function were also assessed. Results: In total, 60% of the participants were smokers, 27% reported a history of problems with alcohol use, 35% reported current substance use (not including alcohol), and 68% reported lifetime substance use (cannabis and psychostimulants were most commonly used). Cannabis use and gender had independent effects on age at onset of psychosis, after adjusting for alcohol misuse and use of other drugs. Conclusions: The strong association between self-reported cannabis use and earlier onset of psychosis provides further evidence that schizophrenia may be precipitated by cannabis use and/or that the early onset of symptoms is a risk factor for cannabis use.
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Cites
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Self-citationSubstance abuse in schizophrenia: a review of the literature and a study of correlates in Sweden
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The social and economic burden of treatment-resistant schizophrenia: a systematic literature review
Kennedy, J. L., Altar, C. A., Taylor, D. L., Degtiar, I., & Hornberger, J. C. (2014) · International Clinical Psychopharmacology · doi:10.1097/yic.0b013e32836508e6 · Cited by 392
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Self-citationReasons for increased substance use in psychosis
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Tobacco Use Before, At, and After First-Episode Psychosis: A Systematic Meta-Analysis
Myles, N., Newall, H. D., Curtis, J., Nielssen, O., Shiers, D., & Large, M. (2012) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.11r07222 · Cited by 158
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Predictors of Relapse and Functioning in First-Episode Psychosis: A Two-Year Follow-Up Study
Bergé, D., Mané, A., Salgado, P., Cortizo, R., Garnier, C., Gomez, L., Diez-Aja, C., Bulbena, A., & Pérez, V. (2016) · Psychiatric Services · doi:10.1176/appi.ps.201400316 · Cited by 96
Beary, M., Hodgson, R., & Wildgust, H. J. (2012) · Journal of Psychopharmacology · doi:10.1177/0269881112440512 · Cited by 79
Gleason, K. A., Birnbaum, S. G., Shukla, A., & Ghose, S. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.122 · Cited by 77
Interventions for co-occurring addictive and other mental disorders (AMDs)
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Metadata
- Authors
- Barnes, T. R. E., Mutsatsa, S. H., Hutton, S. B., Watt, H. C., & Joyce, E. M.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2006-03
- Volume
- 188
- Issue
- 3
- Pages
- 237-242
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2161346464
- Cited by
- 271
- References
- 4
- FWCI
- 11.88
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
