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Cited by 601Schizophrenia research and treatmentMental Health Treatment and AccessSuicide and Self-Harm Studies

The DOI matches its Crossref record; 29 of the 30 references it cites were found in a registry or an index.

Twenty-five year mortality of a community cohort with schizophrenia

Open access
Brown, Steve, Kim, Miranda, Mitchell, Clemence, Inskip, Hazel·2010·British Journal of Psychiatry
DOI 10.1192/bjp.bp.109.067512PMC PMC4560167
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Abstract

Background: People with schizophrenia have significantly raised mortality but we do not know how these mortality patterns in the UK have changed since the 1990s. Aims: To measure the 25-year mortality of people with schizophrenia with particular focus on changes over time. Method: Prospective record linkage study of the mortality of a community cohort of 370 people with schizophrenia. Results: The cohort had an all-cause standardised mortality ratio of 289 (95% CI 247–337). Most deaths were from the common causes seen in the general population. Unnatural deaths were concentrated in the first 5 years of follow-up. There was an indication that cardiovascular mortality may have increased relative to the general population ( P = 0.053) over the course of the study. Conclusions: People with schizophrenia have a mortality risk that is two to three times that of the general population. Most of the extra deaths are from natural causes. The apparent increase in cardiovascular mortality relative to the general population should be of concern to anyone with an interest in mental health.

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Research works printed but not linked: 6

  1. 2003, 20th Century Mortality Trends in England and Wales
  2. 2008, The ICD–10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines, Version for 2007
  3. 2006, Statistics on Smoking: England 2006
  4. 1978, International Statistical Classification of Diseases and Related Health Problems (ICD–9)
  5. 2008, Statistics on Deaths Reported to Coroners England and Wales, 2007
  6. 2008, Annual Mortality Statistics

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Metadata

Authors
Brown, S., Kim, M., Mitchell, C., & Inskip, H.
Affiliations
  • Southern Health NHS Foundation Trust (GB)
  • University of Southampton (GB)
Corresponding author
Brown, Steve
ORCID
Venue
British Journal of Psychiatry
Publisher
Royal College of Psychiatrists
Published
2010-02
Volume
196
Issue
2
Pages
116-121
ISSN
  • 0007-1250 (ISSN-L)
  • 1472-1465
DOI
10.1192/bjp.bp.109.067512
PMC
PMC4560167
OpenAlex
W2117811890
Cited by
601
References
30
Citations by year
2026: 7 · 2025: 20 · 2024: 39 · 2023: 29 · 2022: 24 · 2021: 37 · 2020: 36 · 2019: 43 · 2018: 45 · 2017: 39 · 2016: 46 · 2015: 50 · 2014: 42 · 2013: 62 · 2012: 42
FWCI
30.97
Type
journal article
Language
en
Open access
Licence
www.cambridge.org/core/terms (unspecified, 2892 d)
Locations
  • The British Journal of Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • ePrints Soton (University of Southampton) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
  • Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
Keywords
schizophrenia, mortality, all-cause mortality, cardiovascular mortality, unnatural death, natural death, mortality trends, community-based cohort, data linkage
MeSH terms
Adolescent, Adult, Aged, Cardiovascular Diseases, England, Epidemiologic Methods, Female, Humans, Male, Middle Aged, Mortality, Schizophrenia, Sex Factors, Smoking, Young Adult

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