The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder
Open accessAbstract
Background: Attention-deficit hyperactivity disorder (ADHD) is associated with bipolar disorder and schizophrenia, and it has been suggested that combined bipolar disorder and ADHD is aetiologically distinct from the pure disorders. Aims: To clarify whether ADHD shares genetic and environmental factors with bipolar disorder and schizophrenia. Method: By linking longitudinal Swedish national registers, we identified 61 187 persons with ADHD (the proband group) and their first- and second-degree relatives, and matched them with a control group of people without ADHD and their corresponding relatives. Conditional logistic regression was used to determine the risks of bipolar disorder and schizophrenia in the relatives of the two groups. Results: First-degree relatives of the ADHD proband group were at increased risk of both bipolar disorder (odds ratio (OR) = 1.84−2.54 for parents, offspring and full siblings) and schizophrenia (OR = 1.71−2.22 for parents, offspring and full siblings). The risks of bipolar disorder and schizophrenia among second-degree relatives were substantially lower than among full siblings. Conclusions: These findings suggest that the co-occurrence of ADHD and bipolar disorder as well as ADHD and schizophrenia is due to shared genetic factors, rather than representing completely aetiologically distinct subsyndromes.
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Kessler, R. C., Adler, L., Barkley, R., Biederman, J., Conners, C. K., Demler, O., Faraone, S. V., Greenhill, L. L., Howes, M. J., Secnik, K., et al. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.4.716 · Cited by 3,886
Willcutt, E. G., Doyle, A. E., Nigg, J. T., Faraone, S. V., & Pennington, B. F. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.02.006 · Cited by 3,568
Molecular genetics of attention-deficit/hyperactivity disorder
Faraone, S. V., Perlis, R. H., Doyle, A. E., Smoller, J. W., Goralnick, J. J., Holmgren, M. A., & Sklar, P. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.024 · Cited by 2,357
Schizophrenia as a Complex Trait: Evidence From a Meta-analysis of Twin Studies
Sullivan, P. F., Kendler, K. S., & Neale, M. C. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.12.1187 · Cited by 2,356
Williams, N. M., Zaharieva, I., Martin, A., Langley, K., Mantripragada, K., Fossdal, R., Stefansson, H., Stefansson, K., Magnusson, P., Gudmundsson, O. O., et al. (2010) · The Lancet · doi:10.1016/s0140-6736(10)61109-9 · Cited by 572
The cognitive neuroscience of schizophrenia.
Barch, D. M. (2005) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.143959 · Cited by 437
Molecular Genetics of Attention Deficit Hyperactivity Disorder
Faraone, S. V., & Mick, E. (2010) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2009.12.004 · Cited by 411
Hansson, S. L., Svanströmröjvall, A., Rastam, M., Gillberg, C., Gillberg, C., & Anckarsäter, H. (2005) · British Journal of Psychiatry · doi:10.1192/bjp.187.3.262 · Cited by 208
Recurrence risks for schizophrenia in a Swedish National Cohort
LICHTENSTEIN, P., BJÖRK, C., HULTMAN, C. M., SCOLNICK, E., SKLAR, P., & SULLIVAN, P. F. (2006) · Psychological Medicine · doi:10.1017/s0033291706008385 · Cited by 197
Self-citationGrozeva, D. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.25 · Cited by 192
Cited by
ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Demontis, D., Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., Agerbo, E., Baldursson, G., et al. (2019) · Nature Genetics · doi:10.1038/s41588-018-0269-7 · Cited by 2,203
Genetics of attention deficit hyperactivity disorder
Faraone, S. V., & Larsson, H. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0070-0 · Cited by 1,338
Self-citationResearch Review: Polygenic methods and their application to psychiatric traits
Wray, N. R., Lee, S. H., Mehta, D., Vinkhuyzen, A. A. E., Dudbridge, F., & Middeldorp, C. M. (2014) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12295 · Cited by 666
Larsson, H., Chang, Z., D'Onofrio, B. M., & Lichtenstein, P. (2014) · Psychological Medicine · doi:10.1017/s0033291713002493 · Cited by 364
Self-citationChang, Z., Lichtenstein, P., D’Onofrio, B. M., Sjölander, A., & Larsson, H. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.4174 · Cited by 293
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Metadata
- Authors
- Larsson, H., Rydén, E., Boman, M., Långström, N., Lichtenstein, P., & Landén, M.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2013-08
- Volume
- 203
- Issue
- 2
- Pages
- 103-106
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2117177609
- Cited by
- 190
- References
- 11
- FWCI
- 12.76
- Type
- journal article
- Language
- en
- Open access
- bronze
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