Cited by 184Maternal Mental Health During Pregnancy and PostpartumChild Abuse and TraumaChild and Adolescent Psychosocial and Emotional Development

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Maternal depression during pregnancy and offspring depression in adulthood: Role of child maltreatment

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Plant, Dominic T., Pariante, Carmine M., Sharp, Deborah, Pawlby, Susan·2015·British Journal of Psychiatry

DOI 10.1192/bjp.bp.114.156620PMC PMC4555443

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Abstract

BACKGROUND: Studies have shown that maternal depression during pregnancy predicts offspring depression in adolescence. Child maltreatment is also a risk factor for depression. AIMS: To investigate (a) whether there is an association between offspring exposure to maternal depression in pregnancy and depression in early adulthood, and (b) whether offspring child maltreatment mediates this association. METHOD: Prospectively collected data on maternal clinical depression in pregnancy, offspring child maltreatment and offspring adulthood (18-25 years) DSM-IV depression were analysed in 103 mother-offspring dyads of the South London Child Development Study. RESULTS: Adult offspring exposed to maternal depression in pregnancy were 3.4 times more likely to have a DSM-IV depressive disorder, and 2.4 times more likely to have experienced child maltreatment, compared with non-exposed offspring. Path analysis revealed that offspring experience of child maltreatment mediated the association between exposure to maternal depression in pregnancy and depression in adulthood. CONCLUSIONS: Maternal depression in pregnancy is a key vulnerability factor for offspring depression in early adulthood.

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Additional file 3 of Early intervention to prevent adverse child emotional and behavioural development following maternal depression in pregnancy: study protocol for a randomised controlled trial
Milgrom, J., Hirshler, Y., Holt, C., Skouteris, H., Galbally, M., East, C., Glover, V. A. S., Reece, J., O’Donnell, K. J., Walker, S. P., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26608554
Additional file 1 of Early intervention to prevent adverse child emotional and behavioural development following maternal depression in pregnancy: study protocol for a randomised controlled trial
Milgrom, J., Hirshler, Y., Holt, C., Skouteris, H., Galbally, M., East, C., Glover, V. A. S., Reece, J., O’Donnell, K. J., Walker, S. P., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26608548
Additional file 2 of Early intervention to prevent adverse child emotional and behavioural development following maternal depression in pregnancy: study protocol for a randomised controlled trial
Milgrom, J., Hirshler, Y., Holt, C., Skouteris, H., Galbally, M., East, C., Glover, V. A. S., Reece, J., O’Donnell, K. J., Walker, S. P., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26608551
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Authors: Plant, D. T., Pariante, C. M., Sharp, D., & Pawlby, S.
Affiliations: King's College London (GB)
Corresponding author: Plant, Dominic T.
ORCID: Plant, Dominic T.
Pariante, Carmine M.
Pawlby, Susan
Venue: British Journal of Psychiatry
Publisher: Royal College of Psychiatrists
Published: 2015-09
Volume: 207
Issue: 3
Pages: 213-220
ISSN: 0007-1250 (ISSN-L)
1472-1465
DOI: 10.1192/bjp.bp.114.156620
PMC: PMC4555443
OpenAlex: W1857560301
Cited by: 184
References: 59
Citations by year: 2026: 8 · 2025: 13 · 2024: 15 · 2023: 15 · 2022: 18 · 2021: 21 · 2020: 27 · 2019: 21 · 2018: 17 · 2017: 18 · 2016: 9 · 2015: 2
FWCI: 16.41
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
creativecommons.org/licenses/by/3.0/ (unspecified, 854 d)
Locations: The British Journal of Psychiatry (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
Research Portal (King's College London) (submittedVersion, cc-by)
Funders: Wellcome Trust
Psychiatry Research Trust
National Institute for Health and Care Research
King's College London
Cardiff University
Medical Research Council (MR/J002739/1)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords: maternal depression, pregnancy, offspring depression, early adulthood, child abuse, mediation, intergenerational transmission, vulnerability factors
MeSH terms: Adolescent, Adult, Child, Child Abuse, Child, Preschool, Depressive Disorder, Female, Humans, Longitudinal Studies, Pregnancy, Pregnancy Complications, Prenatal Exposure Delayed Effects, Prospective Studies, Depression, Postpartum, Adult Survivors of Child Abuse, Young Adult

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Maternal depression during pregnancy and offspring depression in adulthood: Role of child maltreatment

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