Evidence for differential effects of apoE3 and apoE4 on HDL metabolism

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ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.

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Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E

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[24] Nondenaturing polyacrylamide gradient gel electrophoresis

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Abnormal in vivo metabolism of apolipoprotein E4 in humans.

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Apo E structure determines VLDL clearance and atherosclerosis risk in mice

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Apolipoprotein E distribution among human plasma lipoproteins: role of the cysteine-arginine interchange at residue 112

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Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice

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Human Intestinal Lipoproteins

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Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption.

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ApoE polymorphism and predisposition to coronary heart disease in youths of different European populations. The EARS Study. European Atherosclerosis Research Study.

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Overexpression and Accumulation of Apolipoprotein E as a Cause of Hypertriglyceridemia

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A plasma lipoprotein containing only apolipoprotein Eand with gamma mobility on electrophoresis releases cholesterol fromcells.

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Increased prebeta-high density lipoprotein, apolipoprotein AI, and phospholipid in mice expressing the human phospholipid transfer protein and human apolipoprotein AI transgenes.

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Genetic Background Determines the Extent of Atherosclerosis in ApoE-Deficient Mice

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Plasma Phospholipid Transfer Protein

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Increased sphingomyelin content of plasma lipoproteins in apolipoprotein E knockout mice reflects combined production and catabolic defects and enhances reactivity with mammalian sphingomyelinase.

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Differential distribution of apolipoprotein E isoforms in human plasma lipoproteins.

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Phenotype-dependent differences in apolipoprotein E metabolism and in cholesterol homeostasis in human monocyte-derived macrophages.

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Low Levels of Extrahepatic Nonmacrophage ApoE Inhibit Atherosclerosis Without Correcting Hypercholesterolemia in ApoE-Deficient Mice

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Phospholipid transfer protein gene knock-out mice have low high density lipoprotein levels, due to hypercatabolism, and accumulate apoA-IV-rich lamellar lipoproteins

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Overexpression of Hepatic Lipase in Transgenic Mice Decreases Apolipoprotein B-containing and High Density Lipoproteins

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Decreased selective uptake of high density lipoprotein cholesteryl esters in apolipoprotein E knock-out mice

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Reverse Cholesterol Transport in Plasma of Patients With Different Forms of Familial HDL Deficiency

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Hydrophobic patches on protein subunit interfaces: Characteristics and prediction

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Transfer of human lymph chylomicron constituents to other lipoprotein density fractions during in vitro lipolysis

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Transcriptional and post-transcriptional control of apolipoprotein E gene expression in differentiating human monocytes.

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Lipoprotein lipase- and hepatic triglyceride lipase-promoted very low density lipoprotein degradation proceeds via an apolipoprotein E-dependent mechanism

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Apolipoprotein effects on the lipolysis of perfused triglyceride by heparin-immobilized milk lipase.

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Influence of macrophage-derived apoprotein E on plasma lipoprotein distribution of apolipoprotein A-I in apoprotein E-deficient mice

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Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation

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Lead (Pb) and neurodevelopment: A review on exposure and biomarkers of effect (BDNF, HDL) and susceptibility

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Role of the N- and C-Terminal Domains in Binding of Apolipoprotein E Isoforms to Heparan Sulfate and Dermatan Sulfate: A Surface Plasmon Resonance Study

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Differential effects of apoE4 and activation of ABCA1 on brain and plasma lipoproteins

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Apolipoprotein (apo) E genotype and apoE concentration determine binding of normal very low density lipoproteins to HepG2 cell surface receptors.

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Complex effects of inhibiting hepatic apolipoprotein B100 synthesis in humans

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The Recycling of Apolipoprotein E in Primary Cultures of Mouse Hepatocytes

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