The DOI matches its Crossref record; 195 of the 195 references it cites were found in a registry or an index.
The Critical Role of Mast Cells in Allergy and Inflammation
Abstract
Abstract: Mast cells are well known for their involvement in allergic and anaphylactic reactions, but recent findings implicate them in a variety of inflammatory diseases affecting different organs, including the heart, joints, lungs, and skin. In these cases, mast cells appear to be activated by triggers other than aggregation of their IgE receptors (FcɛRI), such as anaphylatoxins, immunoglobulin‐free light chains, superantigens, neuropeptides, and cytokines leading to selective release of mediators without degranulation. These findings could explain inflammatory diseases, such as asthma, atopic dermatitis, coronary inflammation, and inflammatory arthritis, all of which worsen by stress. It is proposed that the pathogenesis of these diseases involve mast cell activation by local release of corticotropin‐releasing hormone (CRH) or related peptides. Combination of CRH receptor antagonists and mast cell inhibitors may present novel therapeutic interventions.
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MAST CELLS AS “TUNABLE” EFFECTOR AND IMMUNOREGULATORY CELLS: Recent Advances
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Cited by
Differential release of mast cell mediators and the pathogenesis of inflammation
Theoharides, T. C., Kempuraj, D., Tagen, M., Conti, P., & Kalogeromitros, D. (2007) · Immunological Reviews · doi:10.1111/j.1600-065x.2007.00519.x · Cited by 425
Self-citationKey role of CRF in the skin stress response system
Slominski, A. T., Zmijewski, M. A., Zbytek, B., Tobin, D. J., Theoharides, T. C., & Rivier, J. (2013) · Endocrine Reviews · doi:10.1210/er.2012-1092 · Cited by 400
Self-citationMediators of Chronic Pruritus in Atopic Dermatitis: Getting the Itch Out?
Mollanazar, N. K., Smith, P. K., & Yosipovitch, G. (2016) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-015-8488-5 · Cited by 353
Inflammation is Present in Early Human Tendinopathy
Millar, N. L., Hueber, A. J., Reilly, J. H., Xu, Y., Fazzi, U. G., Murrell, G. A. C., & McInnes, I. B. (2010) · The American Journal of Sports Medicine · doi:10.1177/0363546510372613 · Cited by 287
Mast Cells Increase Vascular Permeability by Heparin-Initiated Bradykinin Formation In Vivo
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Metadata
- Authors
- THEOHARIDES, T. C., & KALOGEROMITROS, D.
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 2006-11
- Volume
- 1088
- Issue
- 1
- Pages
- 78-99
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- OpenAlex
- W1971977052
- Cited by
- 291
- References
- 195
- FWCI
- 6.09
- Type
- journal article
- Language
- en
- Open access
- closed
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- THEOHARIDES, T. C., & KALOGEROMITROS, D. (2006). The Critical Role of Mast Cells in Allergy and Inflammation. Annals of the New York Academy of Sciences. https://doi.org/10.1196/annals.1366.025
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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