The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Model-Based Clustering, Discriminant Analysis, and Density Estimation
Abstract
Cluster analysis is the automated search for groups of related observations in a dataset. Most clustering done in practice is based largely on heuristic but intuitively reasonable procedures, and most clustering methods available in commercial software are also of this type. However, there is little systematic guidance associated with these methods for solving important practical questions that arise in cluster analysis, such as how many clusters are there, which clustering method should be used, and how should outliers be handled. We review a general methodology for model-based clustering that provides a principled statistical approach to these issues. We also show that this can be useful for other problems in multivariate analysis, such as discriminant analysis and multivariate density estimation. We give examples from medical diagnosis, minefield detection, cluster recovery from noisy data, and spatial density estimation. Finally, we mention limitations of the methodology and discuss recent developments in model-based clustering for non-Gaussian data, high-dimensional datasets, large datasets, and Bayesian estimation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Maximum Likelihood from Incomplete Data Via the EM Algorithm
Dempster, A. P., Laird, N. M., & Rubin, D. B. (1977) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1977.tb01600.x · Cited by 50,444
Cluster analysis and display of genome-wide expression patterns
Eisen, M. B., Spellman, P. T., Brown, P. O., & Botstein, D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14863 · Cited by 16,184
Finding Groups in Data: An Introduction to Cluster Analysis
Kaufman, L., & Rousseeuw, P. J. (1990) · Wiley Series in Probability and Statistics · doi:10.1002/9780470316801 · Cited by 7,344
An entropy criterion for assessing the number of clusters in a mixture model
Celeux, G., & Soromenho, G. (1996) · Journal of Classification · doi:10.1007/bf01246098 · Cited by 2,448 · cited 3×
“Cheeseman and Stutz (1995) and Chickering and Heckerman (1997) used a different approximation to the integrated likelihood; other approaches include an informational complexity criterion called ICOMP (Bozdogan 1994), an entropy criterion called NEC (Celeux and Soromenho 1996; Biernacki, Celeux, and Govaert 1999), the…”
Method
Cited by
McLachlan, G., & Peel, D. (2000) · Wiley Series in Probability and Statistics · doi:10.1002/0471721182 · Cited by 10,991
Hierarchical Dirichlet Processes
Teh, Y. W., Jordan, M. I., Beal, M. J., & Blei, D. M. (2006) · Journal of the American Statistical Association · doi:10.1198/016214506000000302 · Cited by 2,120
A Comprehensive Survey of Clustering Algorithms
Xu, D., & Tian, Y. (2015) · Annals of Data Science · doi:10.1007/s40745-015-0040-1 · Cited by 1,939
Single-cell genome sequencing: current state of the science
Gawad, C., Koh, W., & Quake, S. R. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2015.16 · Cited by 1,334
Clustering trees: a visualization for evaluating clusterings at multiple resolutions
Zappia, L., & Oshlack, A. (2018) · GigaScience · doi:10.1093/gigascience/giy083 · Cited by 1,064
Phenomapping for Novel Classification of Heart Failure With Preserved Ejection Fraction
Shah, S. J., Katz, D. H., Selvaraj, S., Burke, M. A., Yancy, C. W., Gheorghiade, M., Bonow, R. O., Huang, C.-C., & Deo, R. C. (2015) · Circulation · doi:10.1161/circulationaha.114.010637 · Cited by 1,157
The functional diversity of retinal ganglion cells in the mouse
Baden, T., Berens, P., Franke, K., Román Rosón, M., Bethge, M., & Euler, T. (2016) · Nature · doi:10.1038/nature16468 · Cited by 999
Hippo Pathway Activity Influences Liver Cell Fate
Yimlamai, D., Christodoulou, C., Galli, G. G., Yanger, K., Pepe-Mooney, B., Gurung, B., Shrestha, K., Cahan, P., Stanger, B. Z., & Camargo, F. D. (2014) · Cell · doi:10.1016/j.cell.2014.03.060 · Cited by 857
A framework for feature selection in clustering
Witten, D. M., & Tibshirani, R. (2010) · Journal of the American Statistical Association · doi:10.1198/jasa.2010.tm09415 · Cited by 696
The determination of standard metabolic rate in fishes
Chabot, D., Steffensen, J. F., & Farrell, A. P. (2016) · Journal of Fish Biology · doi:10.1111/jfb.12845 · Cited by 667
High-dimensional data clustering
Bouveyron, C., Girard, S., & Schmid, C. (2007) · Computational Statistics & Data Analysis · doi:10.1016/j.csda.2007.02.009 · Cited by 382
The cis-regulatory dynamics of embryonic development at single-cell resolution
Cusanovich, D. A., Reddington, J. P., Garfield, D. A., Daza, R. M., Aghamirzaie, D., Marco-Ferreres, R., Pliner, H. A., Christiansen, L., Qiu, X., Steemers, F. J., et al. (2018) · Nature · doi:10.1038/nature25981 · Cited by 363
Deconstructing transcriptional heterogeneity in pluripotent stem cells
Kumar, R. M., Cahan, P., Shalek, A. K., Satija, R., Jay DaleyKeyser, A., Li, H., Zhang, J., Pardee, K., Gennert, D., Trombetta, J. J., et al. (2014) · Nature · doi:10.1038/nature13920 · Cited by 356
Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells
Miao, Y., Yang, H., Levorse, J., Yuan, S., Polak, L., Sribour, M., Singh, B., Rosenblum, M. D., & Fuchs, E. (2019) · Cell · doi:10.1016/j.cell.2019.03.025 · Cited by 299
An Approach for Determining the Number of Clusters in a Model-Based Cluster Analysis
Akogul, S., & Erisoglu, M. (2017) · Entropy · doi:10.3390/e19090452 · Cited by 269
Discovery of brainwide neural-behavioral maps via multiscale unsupervised structure learning
Vogelstein, J. T., Park, Y., Ohyama, T., Kerr, R. A., Truman, J. W., Priebe, C. E., & Zlatic, M. (2014) · Science · doi:10.1126/science.1250298 · Cited by 218
Circadian Phase Variation in Bipolar I Disorder
Mansour, H. A., Wood, J., Chowdari, K. V., Dayal, M., Thase, M. E., Kupfer, D. J., Monk, T. H., Devlin, B., & Nimgaonkar, V. L. (2005) · Chronobiology International · doi:10.1081/cbi-200062413 · Cited by 204
Liu, L., Sabo, A., Neale, B. M., Nagaswamy, U., Stevens, C., Lim, E., Bodea, C. A., Muzny, D., Reid, J. G., Banks, E., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003443 · Cited by 135
Neuropathological and transcriptomic characteristics of the aged brain
Miller, J. A., Guillozet-Bongaarts, A., Gibbons, L. E., Postupna, N., Renz, A., Beller, A. E., Sunkin, S. M., Ng, L., Rose, S. E., Smith, K. A., et al. (2017) · eLife · doi:10.7554/elife.31126 · Cited by 134
Expression Quantitative Trait Loci Mapping With Multivariate Sparse Partial Least Squares Regression
Chun, H., & Keleş, S. (2009) · Genetics · doi:10.1534/genetics.109.100362 · Cited by 97
Berthoz, S., Lalanne, C., Crane, L., & Hill, E. L. (2013) · Psychiatry Research · doi:10.1016/j.psychres.2013.05.014 · Cited by 97
Population identification using genetic data
Lawson, D. J., & Falush, D. (2012) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-082410-101510 · Cited by 89
Reis, G. F., Yang, G., Szpankowski, L., Weaver, C., Shah, S. B., Robinson, J. T., Hays, T. S., Danuser, G., & Goldstein, L. S. B. (2012) · Molecular Biology of the Cell · doi:10.1091/mbc.e11-11-0938 · Cited by 80
Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo
Gunawardena, S., Yang, G., & Goldstein, L. S. B. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt237 · Cited by 66
Polster, A., Van Oudenhove, L., Jones, M., Öhman, L., Törnblom, H., & Simrén, M. (2017) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14207 · Cited by 65
Model-based clustering of meta-analytic functional imaging data
Neumann, J., Cramon, D. Y. V., & Lohmann, G. (2008) · Human Brain Mapping · doi:10.1002/hbm.20380 · Cited by 57
Subedi, S., & McNicholas, P. D. (2014) · Advances in Data Analysis and Classification · doi:10.1007/s11634-014-0165-7 · Cited by 51
Applying network theory to animal movements to identify properties of landscape space use
Bastille‐Rousseau, G., Douglas‐Hamilton, I., Blake, S., Northrup, J. M., & Wittemyer, G. (2018) · Ecological Applications · doi:10.1002/eap.1697 · Cited by 51
Influence of birth cohort on age of onset cluster analysis in bipolar I disorder
Bauer, M., Glenn, T., Alda, M., Andreassen, O. A., Angelopoulos, E., Ardau, R., Baethge, C., Bauer, R., Bellivier, F., Belmaker, R. H., et al. (2015) · European Psychiatry · doi:10.1016/j.eurpsy.2014.10.005 · Cited by 39
Monoallelic silencing and haploinsufficiency in early murine intestinal neoplasms
Amos-Landgraf, J. M., Irving, A. A., Hartman, C., Hunter, A., Laube, B., Chen, X., Clipson, L., Newton, M. A., & Dove, W. F. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120753109 · Cited by 16
Gendered Analysis of Fatal Crashes among Young Drivers in Alabama, USA
Adanu, E. K., Penmetsa, P., Jones, S., & Smith, R. (2018) · Safety · doi:10.3390/safety4030029 · Cited by 15
Mahmoud, O., Dudbridge, F., Smith, G. D., Munafo, M., & Tilling, K. (2020) · doi:10.1101/2020.01.31.928077 · Cited by 15
Luppino, F., Adzhubei, I. A., Cassa, C. A., & Toth-Petroczy, A. (2023) · Nature Communications · doi:10.1038/s41467-023-37661-z · Cited by 12
Adama, S., & Bogdan, M. (2026) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2026.1797090 · Cited by 1
Metadata
- Authors
- Fraley, C., & Raftery, A. E.
- Venue
- Journal of the American Statistical Association
- Publisher
- Informa UK Limited
- Published
- 2002-06
- Volume
- 97
- Issue
- 458
- Pages
- 611-631
- ISSN
- 0162-1459 (ISSN-L)
- 1537-274X
- OpenAlex
- W2011832962
- Cited by
- 4,257
- References
- 4
- FWCI
- 48.85
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.