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Response and resistance in a non-small-cell lung cancer patient with an epidermal growth factor receptor mutation and leptomeningeal metastases treated with high-dose gefitinib
Open accessAbstract
HIV and human papillomavirus (HPV) coinfected patients are at high risk of developing precancerous anal lesions (anal intraepithelial neoplasia) and anal malignancies.1 The natural history (that is, progression and persistence) of HPV-associated lesions is accelerated by HIV-related immunosuppression, which may result in the reactivation of previously acquired HPV infection and loss of control of HPV viral replication.2 The longer life expectancy of these coinfected patients in the era of HAART provides an opportunity for invasive anal carcinoma to develop from its dysplastic precursor.The prognosis of anal squamous cell carcinoma is poor in HIV-positive patients, who often present with advanced tumors.3 The appropriate treatment of patients with advanced anal cancer and HIV infection is uncertain.4 Concomitant radiation therapy and chemotherapy (fluorouracil and mitomycin-C) is the current standard of care for HIV-negative patients with invasive anal carcinoma, and that approach has been investigated and applied successfully in HIV-positive patients with similar anal cancers, particularly those with CD4ϩ T-lymphocyte counts greater than 200 cells/L.5,6 HIV-positive patients with anal cancer treated with HAART tend to fare better than those patients who are not receiving HAART.7 It is prudent to point out that our patient never had an anal Papanicolaou (Pap) test (Fig 3, high-grade dysplastic squamous cells; ThinPrep, Cytyc Corporation, Marlborough, MA).HIV-associated anal carcinoma appears to mirror cervical carcinoma in unscreened women, presenting late in the course of the disease and having a protracted, ultimately fatal, course.8 Screening of HIV-positive patients for anorectal dysplasia and/or malignancy by means of an anal Pap test could save lives.9
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Cites
Lynch, T. J., Bell, D. W., Sordella, R., Gurubhagavatula, S., Okimoto, R. A., Brannigan, B. W., Harris, P. L., Haserlat, S. M., Supko, J. G., Haluska, F. G., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040938 · Cited by 11,486
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
Paez, J. G., Jänne, P. A., Lee, J. C., Tracy, S., Greulich, H., Gabriel, S., Herman, P., Kaye, F. J., Lindeman, N., Boggon, T. J., et al. (2004) · Science · doi:10.1126/science.1099314 · Cited by 9,368
Self-citationEGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
Kobayashi, S., Boggon, T. J., Dayaram, T., Jänne, P. A., Kocher, O., Meyerson, M., Johnson, B. E., Eck, M. J., Tenen, D. G., & Halmos, B. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa044238 · Cited by 3,964
Self-citationPao, W., Miller, V. A., Politi, K. A., Riely, G. J., Somwar, R., Zakowski, M. F., Kris, M. G., & Varmus, H. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020073 · Cited by 3,527
Baselga, J., Rischin, D., Ranson, M., Calvert, H., Raymond, E., Kieback, D. G., Kaye, S. B., Gianni, L., Harris, A., Bjork, T., et al. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.2002.03.100 · Cited by 829
Mukohara, T., Engelman, J. A., Hanna, N. H., Yeap, B. Y., Kobayashi, S. S., Lindeman, N. I., Halmos, B., Pearlberg, J., Tsuchihashi, Z., Cantley, L. C., et al. (2005) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dji238 · Cited by 314
Self-citationNakagawa, K., Tamura, T., Negoro, S., Kudoh, S., Yamamoto, N., Yamamoto, N., Takeda, K., Swaisland, H., Nakatani, I., Hirose, M., et al. (2003) · Annals of Oncology · doi:10.1093/annonc/mdg250 · Cited by 277
Omuro, A. M. P., Kris, M. G., Miller, V. A., Franceschi, E., Shah, N. T., Milton, D. T., & Abrey, L. E. (2005) · Cancer · doi:10.1002/cncr.21033 · Cited by 227
A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening
Jänne, P. A., Borras, A. M., Kuang, Y., Rogers, A. M., Joshi, V. A., Liyanage, H., Lindeman, N., Lee, J. C., Halmos, B., Maher, E. A., et al. (2006) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-05-2047 · Cited by 214
Self-citationJones, H., Stafford, L. E., Swaisland, H., & Payne, R. K. (2002) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/s0731-7085(02)00014-6 · Cited by 63
Cited by
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Travis, W. D., Brambilla, E. M., Noguchi, M., Nicholson, A. G., Geisinger, K. R., Yatabe, Y., Beer, D. G., Powell, C. A., Riely, G. J., Schil, P. E. V., et al. (2011) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e318206a221 · Cited by 4,834
Self-citationRational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
Pao, W., & Chmielecki, J. (2010) · Nature Reviews Cancer · doi:10.1038/nrc2947 · Cited by 1,083
“This observation may be due to a lack of selective pressure, as the concentration of EGFR TKI that reaches the brain is 100-fold less than that found in bloo”
BackgroundAcquired resistance to TKIs in solid tumours: learning from lung cancer
Camidge, D. R., Pao, W., & Sequist, L. V. (2014) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2014.104 · Cited by 862
Jackman, D., Pao, W., Riely, G. J., Engelman, J. A., Kris, M. G., Jänne, P. A., Lynch, T., Johnson, B. E., & Miller, V. A. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.24.7049 · Cited by 793
Self-citationMechanisms of acquired resistance to first- and second-generation EGFR tyrosine kinase inhibitors
Westover, D., Zugazagoitia, J., Cho, B. C., Lovly, C. M., & Paz-Ares, L. (2018) · Annals of Oncology · doi:10.1093/annonc/mdx703 · Cited by 766
Weickhardt, A. J., Scheier, B., Burke, J. M., Gan, G., Lu, X., Bunn, P. A., Aisner, D. L., Gaspar, L. E., Kavanagh, B. D., Doebele, R. C., et al. (2012) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e3182745948 · Cited by 684
Oxnard, G. R., Arcila, M. E., Sima, C. S., Riely, G. J., Chmielecki, J., Kris, M. G., Pao, W., Ladanyi, M., & Miller, V. A. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-2692 · Cited by 627
Costa, D. B., Shaw, A. T., Ou, S. I., Solomon, B., Riely, G. J., Ahn, M., Zhou, C., Shreeve, S. M., Selaru, P., Polli, A., et al. (2015) · Journal of Clinical Oncology · doi:10.1200/jco.2014.59.0539 · Cited by 608
CSF Concentration of the Anaplastic Lymphoma Kinase Inhibitor Crizotinib
Costa, D. B., Kobayashi, S. S., Pandya, S. S., Yeo, W.-L., Shen, Z., Tan, W., & Wilner, K. D. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2010.34.1313 · Cited by 603
Clinical pharmacokinetics of tyrosine kinase inhibitors
van Erp, N. P., Gelderblom, H., & Guchelaar, H.-J. (2009) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2009.08.004 · Cited by 503
Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor–Resistant Disease
Ohashi, K., Maruvka, Y. E., Michor, F., & Pao, W. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2012.43.3912 · Cited by 467
Lin, N., Carey, L., Liu, M., Younger, J., Come, S. E., Ewend, M. G., Harris, G. J., Bullitt, E., den Abbeele, A. D. V., Henson, J. W., et al. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.12.3588 · Cited by 456
Pentsova, E. I., Shah, R. H., Tang, J., Boire, A. A., You, D., Briggs, S. R., Omuro, A. M. P., Lin, X., Fleisher, M., Grommes, C., et al. (2016) · Journal of Clinical Oncology · doi:10.1200/jco.2016.66.6487 · Cited by 421
Schuler, M., Wu, Y.-L., Hirsh, V., O’Byrne, K., Yamamoto, N., Mok, T., Popat, S., Sequist, L. V., Massey, D., Zazulina, V., et al. (2016) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2015.11.014 · Cited by 361
Update on Epidermal Growth Factor Receptor Mutations in Non–Small Cell Lung Cancer
Riely, G. J., Politi, K. A., Miller, V. A., & Pao, W. J. (2006) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-0658 · Cited by 363
Oxnard, G. R., Arcila, M. E., Chmielecki, J., Ladanyi, M., Miller, V. A., & Pao, W. J. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-2571 · Cited by 359
Grommes, C., Oxnard, G. R., Kris, M. G., Miller, V. A., Pao, W., Holodny, A. I., Clarke, J. L., & Lassman, A. B. (2011) · Neuro-Oncology · doi:10.1093/neuonc/nor121 · Cited by 349
Carcinomatous meningitis: Leptomeningeal metastases in solid tumors
Chamberlain, M. C., Rhun, É. L., & Taillibert, S. (2013) · Surgical Neurology International · doi:10.4103/2152-7806.111304 · Cited by 342
Teplyuk, N. M., Mollenhauer, B., Gabriely, G., Giese, A., Kim, E. L., Smolsky, M., Kim, R. Y., Saria, M. G., Pastorino, S., Kesari, S. P., et al. (2012) · Neuro-Oncology · doi:10.1093/neuonc/nos074 · Cited by 304
Self-citationTogashi, Y., Masago, K., Masuda, S., Mizuno, T., Fukudo, M., Ikemi, Y., Sakamori, Y., Nagai, H., Kim, Y. H., Katsura, T., et al. (2012) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-012-1929-4 · Cited by 282
Leptomeningeal metastasis from systemic cancer: Review and update on management
Wang, N., Bertalan, M. S., & Brastianos, P. K. (2017) · Cancer · doi:10.1002/cncr.30911 · Cited by 262
Hoffknecht, P., Tufman, A., Wehler, T., Pelzer, T., Wiewrodt, R. G., Schütz, M., Serke, M. H., Stöhlmacher-Williams, J., Märten, A., Huber, R. M., et al. (2014) · Journal of Thoracic Oncology · doi:10.1097/jto.0000000000000380 · Cited by 259
Systemic therapy of brain metastases: non–small cell lung cancer, breast cancer, and melanoma
Chamberlain, M. C., Baik, C. S., Gadi, V. K., Bhatia, S., & Chow, L. Q. M. (2016) · Neuro-Oncology · doi:10.1093/neuonc/now197 · Cited by 224
Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors
Gion, P. D., Kanefendt, F., Lindauer, A., Scheffler, M., Doroshyenko, O., Fuhr, U., Wolf, J., & Jaehde, U. (2011) · Clinical Pharmacokinetics · doi:10.2165/11593320-000000000-00000 · Cited by 224
Héon, S., Yeap, B. Y., Britt, G. J., Costa, D. B., Rabin, M. S., Jackman, D. M., & Johnson, B. E. (2010) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-1588 · Cited by 217
Self-citationClarke, J. L., Pao, W., Wu, N., Miller, V. A., & Lassman, A. B. (2010) · Journal of Neuro-Oncology · doi:10.1007/s11060-010-0128-6 · Cited by 214
Tan, D. S. W., Yom, S. S., Tsao, M. S., Pass, H. I., Kelly, K., Peled, N., Yung, R. C., Wistuba, I. I., Yatabe, Y., Unger, M., et al. (2016) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2016.05.008 · Cited by 201
Remón, J., Rhun, É. L., & Besse, B. (2016) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2016.12.006 · Cited by 196
Kang, M., Ren, M., Yan, L., Fu, Y., Deng, M., & Li, C. (2018) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-018-0845-9 · Cited by 180
RetractedHata, A., Katakami, N., Yoshioka, H., Takeshita, J., Tanaka, K., Nanjo, S., Fujita, S., Kaji, R., Imai, Y., Monden, K., et al. (2013) · Cancer · doi:10.1002/cncr.28364 · Cited by 178
Heon, S., Yeap, B. Y., Lindeman, N. I., Joshi, V. A., Butaney, M., Britt, G. J., Costa, D. B., Rabin, M. S., Jackman, D. M., & Johnson, B. E. (2012) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-12-0357 · Cited by 176
Self-citationPark, J. H., Kim, Y. J., Lee, J., Lee, K., Kim, J. H., Bang, S., Chung, J.-H., Js, K., & Lee, J. S. (2011) · Lung Cancer · doi:10.1016/j.lungcan.2011.11.022 · Cited by 170
Therapy of leptomeningeal metastasis in solid tumors
Mack, F., Baumert, B. G., Schäfer, N., Hattingen, E., Scheffler, B., Herrlinger, U., & Glas, M. (2015) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2015.12.004 · Cited by 172
Lei, Y., Wang, G., Chen, B., Chen, L., Gong, J., & Li, W. (2018) · Oncology Reports · doi:10.3892/or.2018.6762 · Cited by 165
RetractedKoivunen, J. P., Kim, J., Lee, J., Rogers, A. M., Park, J. O., Zhao, X., Naoki, K., Okamoto, I., Nakagawa, K., Yeap, B. Y., et al. (2008) · British Journal of Cancer · doi:10.1038/sj.bjc.6604469 · Cited by 168
Self-citationKatayama, T., Shimizu, J., Suda, K., Onozato, R., Fukui, T., Ito, S., Hatooka, S., Sueda, T., Hida, T., Yatabe, Y., et al. (2009) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e3181b62572 · Cited by 161
HER Family Receptor Abnormalities in Lung Cancer Brain Metastases and Corresponding Primary Tumors
Sun, M., Behrens, C., Feng, L., Ozburn, N. C., Tang, X., Yin, G., Komaki, R. U., Varella‐Garcia, M., Hong, W. K., Aldape, K., et al. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-2921 · Cited by 152
Hata, A., Katakami, N., Yoshioka, H., Kaji, R., Masago, K., Fujita, S., Imai, Y., Nishiyama, A., Ishida, T., Nishimura, Y., et al. (2015) · Journal of Thoracic Oncology · doi:10.1097/jto.0000000000000647 · Cited by 150
Zeng, Q., Wang, J., Cheng, Z., Chen, K., Johnström, P., Varnäs, K., Li, D. Y., Yang, Z. F., & Zhang, X. (2015) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b01073 · Cited by 151
Melanoma central nervous system metastases: current approaches, challenges, and opportunities
Cohen, J. V., Tawbi, H., Margolin, K. A., Amravadi, R., Bosenberg, M., Brastianos, P. K., Chiang, V., de Groot, J., Glitza, I. C., Herlyn, M., et al. (2016) · Pigment Cell & Melanoma Research · doi:10.1111/pcmr.12538 · Cited by 150
Self-citationJamal‐Hanjani, M., & Spicer, J. F. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-2529 · Cited by 146
Small Molecule Kinase Inhibitors for the Treatment of Brain Cancer
Heffron, T. P. (2016) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6b00618 · Cited by 144
De Pas, T., Toffalorio, F., Manzotti, M., Fumagalli, C., Spitaleri, G., Catania, C., Delmonte, A., Giovannini, M., Spaggiari, L., de Braud, F., et al. (2011) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e318227e8c6 · Cited by 138
ALK inhibitors in non-small cell lung cancer: the latest evidence and developments
Sullivan, I., & Planchard, D. (2015) · Therapeutic Advances in Medical Oncology · doi:10.1177/1758834015617355 · Cited by 139
Togashi, Y., Masago, K., Fukudo, M., Terada, T., Fujita, S., Irisa, K., Sakamori, Y., Kim, Y. H., Mio, T., Inui, K., et al. (2010) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e3181e2138b · Cited by 130
Leptomeningeal Metastasis from Non–Small Cell Lung Cancer and Current Landscape of Treatments
Ozcan, G., Singh, M., & Vredenburgh, J. J. (2022) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-22-1585 · Cited by 126
Yi, H. G., Kim, H. J., Kim, Y. J., Han, S., Oh, D., Lee, S., Kim, D., Im, S., Kim, T., Kim, C. S., et al. (2008) · Lung Cancer · doi:10.1016/j.lungcan.2008.10.016 · Cited by 125
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Oxnard, G. R., Morris, M. J., Hodi, F. S., Baker, L. H., Kris, M. G., Venook, A. P., & Schwartz, L. H. (2012) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djs353 · Cited by 126
Umemura, S., Tsubouchi, K., Yoshioka, H., Hotta, K., Takigawa, N., Fujiwara, K., Horita, N., Segawa, Y., Hamada, N., Takata, I., et al. (2012) · Lung Cancer · doi:10.1016/j.lungcan.2012.03.002 · Cited by 122
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Zhao, J., Chen, M., Zhong, W., Zhang, L., Li, L., Xiao, Y., Nie, L., Hu, P., & Wang, M. (2012) · Clinical Lung Cancer · doi:10.1016/j.cllc.2012.06.004 · Cited by 121
Lee, E., Keam, B., Kim, D., Kim, T. M., Lee, S., Chung, D. H., & Heo, D. S. (2013) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e318294c8e8 · Cited by 121
Zeng, Y.-D., Liao, H., Qin, T., Zhang, L., Wei, W.-D., Liang, J.-Z., Xu, F., Dinglin, X.-X., Ma, S.-X., & Chen, L.-K. (2015) · Oncotarget · doi:10.18632/oncotarget.3187 · Cited by 112
Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors
Scheffler, M., Gion, P. D., Doroshyenko, O., Wolf, J., & Fuhr, U. (2011) · Clinical Pharmacokinetics · doi:10.2165/11587020-000000000-00000 · Cited by 110
Lee, Y. J., Choi, H. J., Kim, S. I., Chang, J., Moon, J. W., Park, I. K., Kim, J.-H., & Cho, B. C. (2010) · Cancer · doi:10.1002/cncr.24877 · Cited by 106
Jackman, D. M., Cioffredi, L. A., Jacobs, L., Sharmeen, F., Morse, L. K., Lucca, J. V., Plotkin, S. R., Marcoux, P. J., Rabin, M. S., Lynch, T. J., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.2886 · Cited by 101
Self-citationGroves, M. D. (2010) · Neurosurgery Clinics of North America · doi:10.1016/j.nec.2010.08.006 · Cited by 100
Tang, X., Varella‐Garcia, M., Xavier, A. C., Massarelli, E., Ozburn, N. C., Moran, C. A., & Wistuba, I. I. (2008) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-08-0032 · Cited by 99
Masuda, T., Hattori, N., Hamada, A., Iwamoto, H., Ohshimo, S., Kanehara, M., Ishikawa, N., Fujitaka, K., Haruta, Y., Murai, H., et al. (2011) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-011-1555-6 · Cited by 97
Lee, J., Choi, Y., Han, J., Park, S., Jung, H. A., Su, J.-M., Lee, S., Ahn, J. S., Park, K., & Ahn, M. (2020) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2020.06.018 · Cited by 90
Shukuya, T., Takahashi, T., Naito, T., Kaira, R., Ono, A., Nakamura, Y., Tsuya, A., Kenmotsu, H., Murakami, H., Harada, H., et al. (2011) · Lung Cancer · doi:10.1016/j.lungcan.2011.04.007 · Cited by 90
Management of Brain Metastases in Epidermal Growth Factor Receptor Mutant Non-Small-Cell Lung Cancer
Kelly, W., Shah, N. J., & Subramaniam, D. S. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00208 · Cited by 86
Therapeutic strategy for advanced EGFR mutant non-small-cell lung carcinoma
Cadranel, J. L., Ruppert, A.-M., Beau‐Faller, M., & Wislez, M. (2013) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2013.06.009 · Cited by 83
Taillibert, S., & Chamberlain, M. C. (2018) · Handbook of clinical neurology · doi:10.1016/b978-0-12-811161-1.00013-x · Cited by 81
Takeda, M., Okamoto, I., & Nakagawa, K. (2013) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e31828c28e7 · Cited by 80
Brain Metastases in Oncogene-Addicted Non-Small Cell Lung Cancer Patients: Incidence and Treatment
Remón, J., & Besse, B. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00088 · Cited by 80
Togashi, Y., Masago, K., Fukudo, M., Tsuchido, Y., Okuda, C., Kim, Y. H., Ikemi, Y., Sakamori, Y., Mio, T., Katsura, T., et al. (2011) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-011-1691-z · Cited by 79
Chen, H., & Cheng, X. (2014) · OncoTargets and Therapy · doi:10.2147/ott.s66502 · Cited by 81
Kawamura, T., Hata, A., Takeshita, J., Fujita, S., Hayashi, M., Tomii, K., & Katakami, N. (2015) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-015-2759-y · Cited by 77
Targeted Therapy for Brain Metastases in EGFR-Mutated and ALK-Rearranged Non-Small-Cell Lung Cancer
Baik, C. S., Chamberlain, M. C., & Chow, L. Q. M. (2015) · Journal of Thoracic Oncology · doi:10.1097/jto.0000000000000615 · Cited by 77
Tam, I. Y. S., Leung, E. L., Tin, V. P., Chua, D. T.-T., Sihoe, A. D., Cheng, L., Chung, L.-P., & Wong, M. P. (2009) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-08-1219 · Cited by 76
Berger, L. A., Riesenberg, H., Bokemeyer, C., & Atanackovic, D. (2013) · Lung Cancer · doi:10.1016/j.lungcan.2013.02.004 · Cited by 73
Zeng, Y.-D., Zhang, L., Liao, H., Liang, Y., Xu, F., Liu, J., Dinglin, X.-X., & Chen, L.-K. (2012) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2012.13.3.909 · Cited by 72
Evaluation of Polymer Nanoformulations in Hepatoma Therapy by Established Rodent Models
Wang, Q., Zhang, P., Li, Z., Feng, X., Lv, C., Zhang, H., Xiao, H., Ding, J., & Chen, X. (2019) · Theranostics · doi:10.7150/thno.31683 · Cited by 72
EGFR mutation status in brain metastases of non-small cell lung carcinoma
Burel‐Vandenbos, F., Ambrosetti, D., Coutts, M., & Pédeutour, F. (2012) · Journal of Neuro-Oncology · doi:10.1007/s11060-012-0990-5 · Cited by 72
Lee, H., Chung, T.-S., Ting, L., Tsai, J., Chen, S.-W., Chiou, J., Leung, H. W.-C., & Liu, H. E. (2012) · Radiation Oncology · doi:10.1186/1748-717x-7-181 · Cited by 65
Aw, D. C., Tan, E. H., Chin, T. M., Lim, H. L., Lee, H. Y., & Soo, R. A. (2017) · Asia-Pacific Journal of Clinical Oncology · doi:10.1111/ajco.12687 · Cited by 69
Ulahannan, D., Khalifa, J., Finn, C. F., & Lee, S. M. (2017) · Annals of Oncology · doi:10.1093/annonc/mdx481 · Cited by 63
Carcinomatous Meningitis in Non–Small-Cell Lung Cancer: Response to High-Dose Erlotinib
Dhruva, N., & Socinski, M. A. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.21.0963 · Cited by 64
Zhang, J., Yu, J., Sun, X., & Meng, X. (2014) · Cancer Letters · doi:10.1016/j.canlet.2014.04.019 · Cited by 63
Jacus, M. O., Daryani, V. M., Harstead, K. E., Patel, Y. T., Throm, S. L., & Stewart, C. F. (2015) · Clinical Pharmacokinetics · doi:10.1007/s40262-015-0319-6 · Cited by 60
Qiu, B., Liang, Y., Li, Q.-W., Liu, G.-H., Wang, F., Chen, Z., Liu, M., Zhao, M. D., & Liu, H. (2017) · Clinical Lung Cancer · doi:10.1016/j.cllc.2017.04.002 · Cited by 61
Baek, M. Y., Ahn, H. K., Park, K. R., Park, H.-S., Kang, S. M., Park, I., Kim, Y. S., Hong, J., Sym, S. J., Park, J., et al. (2016) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2015.158 · Cited by 54
Sasaki, S., Yoshioka, Y., Ko, R., Katsura, Y., Namba, Y., Shukuya, T., Kido, K., Iwakami, S., Tominaga, S., & Takahashi, K. (2015) · Respiratory Investigation · doi:10.1016/j.resinv.2015.07.001 · Cited by 53
Zhao, J., Ye, X., Xu, Y., Chen, M., Zhong, W., Sun, Y., Yang, Z., Zhu, G., Gu, Y., & Wang, M. (2016) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-016-3155-y · Cited by 53
How, J., Mann, J., Laczniak, A. N., & Baggstrom, M. Q. (2017) · Clinical Lung Cancer · doi:10.1016/j.cllc.2017.01.013 · Cited by 52
Hata, A., Kaji, R., Fujita, S., & Katakami, N. (2011) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e3181d899bb · Cited by 50
Kaneda, H., Okamoto, I., & Nakagawa, K. (2013) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e3182843771 · Cited by 50
Targeted Therapies in Brain Metastases
Lin, N. (2013) · Current Treatment Options in Neurology · doi:10.1007/s11940-013-0276-z · Cited by 49
Chen, Y., Wang, M., Zhong, W., & Zhao, J. (2013) · Lung Cancer · doi:10.1016/j.lungcan.2013.08.013 · Cited by 48
Tsakonas, G., Petris, L. D., & Ekman, S. (2017) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2017.02.004 · Cited by 48
Wrona, A., Dziadziuszko, R., & Jassem, J. (2018) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2018.10.011 · Cited by 48
Kuiper, J. L., & Smit, E. F. (2013) · Lung Cancer · doi:10.1016/j.lungcan.2012.12.024 · Cited by 46
Tan, C., Cho, B. C., & Soo, R. A. (2017) · Lung Cancer · doi:10.1016/j.lungcan.2017.02.012 · Cited by 45
Conforti, F., Catania, C., Toffalorio, F., Duca, M., Spitaleri, G., Barberis, M. C. P., Noberasco, C., Delmonte, A., Santarpía, M., Lazzari, C., et al. (2013) · Lung Cancer · doi:10.1016/j.lungcan.2013.05.019 · Cited by 43
EGFR-TKI and lung adenocarcinoma with CNS relapse: interest of molecular follow-up
Ruppert, A.-M., Beau‐Faller, M., Neuville, A., Guérin, É., Voegeli, A.-C., Mennecier, B., Legrain, M., Molard, A., Jeung, M.-Y., Gaub, M.-P., et al. (2009) · European Respiratory Journal · doi:10.1183/09031936.00162307 · Cited by 44
Zhou, L., He, J., Xiong, W., Liu, Y., Xiang, J., Yu, Q., Liang, M., Zhou, X., Ding, Z., Huang, M., et al. (2016) · Lung Cancer · doi:10.1016/j.lungcan.2016.04.003 · Cited by 40
High-Dose Crizotinib for Brain Metastases Refractory to Standard-Dose Crizotinib
Kim, Y. H., Ozasa, H., Nagai, H., Sakamori, Y., Yoshida, H., Yagi, Y., Nakaoku, T., & Mishima, M. (2013) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e31829cebbb · Cited by 39
Novel approaches to treating leptomeningeal metastases
Grewal, J., Saria, M. G., & Kesari, S. (2011) · Journal of Neuro-Oncology · doi:10.1007/s11060-011-0686-2 · Cited by 39
Self-citationContinuing EGFR inhibition beyond progression in advanced non-small cell lung cancer
Yap, T. A., Macklin-Doherty, A., & Popat, S. (2017) · European Journal of Cancer · doi:10.1016/j.ejca.2016.10.014 · Cited by 38
Erlotinib for the treatment of brain metastases in non-small cell lung cancer
Brower, J. V., & Robins, H. I. (2016) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2016.1165206 · Cited by 37
Metadata
- Authors
- Jackman, D. M., Holmes, A. J., Lindeman, N., Wen, P. Y., Kesari, S., Borras, A. M., Bailey, C., de Jong, F., Jänne, P. A., & Johnson, B. E.
- Affiliations
- Brigham and Women's Hospital (US)
- Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
- Dana-Farber Cancer Institute (US)
- AstraZeneca (United Kingdom) (GB)
- Analytico Medinet BV, Breda, the Netherlands
- Department of Medical Oncology, Dana-Farber Cancer Institute; Department of Medicine, Brigham and Women’s Hospital; Harvard Medical School, Boston, MA
- Venue
- Journal of Clinical Oncology
- Published
- 2006-09-20
- Volume
- 24
- Issue
- 27
- Pages
- 4517-4520
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W2126767708
- Cited by
- 260
- References
- 10
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 7 · 2023: 11 · 2022: 7 · 2021: 4 · 2020: 10 · 2019: 4 · 2018: 15 · 2017: 18 · 2016: 31 · 2015: 22 · 2014: 18 · 2013: 26 · 2012: 24
- FWCI
- 7.98
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Oncology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Cancer Institute (R01CA114465, P20CA090578, P20 CA 90578-02, 1K12CA87723-01, K12CA087723)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Treatments and Mutations
- Health Sciences › Medicine › Surgery › Colorectal and Anal Carcinomas
- Health Sciences › Medicine › Oncology › HER2/EGFR in Cancer Research
- Keywords
- non-small cell lung cancer, EGFR mutation, leptomeningeal metastasis, gefitinib, drug resistance, EGFR tyrosine kinase inhibitors
- MeSH terms
- Gefitinib, Antineoplastic Agents, Carcinoma, Non-Small-Cell Lung, Humans, Lung Neoplasms, Male, Meningeal Neoplasms, Middle Aged, Mutation, Quinazolines, Treatment Outcome, Drug Resistance, Neoplasm, Protein Kinase Inhibitors, ErbB Receptors
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