The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
CSF Concentration of the Anaplastic Lymphoma Kinase Inhibitor Crizotinib
Open accessAbstract
CSF Concentration of the Anaplastic Lymphoma Kinase Inhibitor Crizotinib Case ReportWe describe the case of a 29-year-old white man with a neversmoking history and EML4-ALK-E20A20 stage IV non-small-cell lung cancer (NSCLC) whose disease had progressed after first-line cisplatin plus pemetrexed and second-line erlotinib.He started crizotinib at 200 mg twice daily and attained significant symptomatic improvement and minor tumor regression of his intrathoracic disease best classified as stable disease. 1 Before start of therapy, brain imaging studies showed no abnormalities.His systemic disease retained radiographic control with crizotinib when he presented with new-onset headaches 7.5 months into his treatment course.Magnetic resonance imaging of the brain disclosed small enhancing masses throughout the supratentorial and infratentorial brain, as well as the leptomeninges.The sagittal view of the T1-weighted sequence shows these masses, with black arrows highlighting some of the lesions (Fig 1).CSF cytology was positive for malignant cells.The patient received 30 Gy of whole-brain radiotherapy.Crizotinib was restarted at 250 mg twice daily during month 8 after the initiation of drug.Two weeks later, CSF and plasma were sampled 5 hours after a dose of crizotinib 250 mg.Concentrations of crizotinib were measured using a validated high-D I A G N O S I S I N O N C O L O G
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Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
Mok, T. S., Wu, Y.-L., Thongprasert, S., Yang, C.-H., Chu, D.-T., Saijo, N., Sunpaweravong, P., Han, B., Margono, B., Ichinose, Y., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810699 · Cited by 8,261
Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR
Maemondo, M., Inoue, A., Kobayashi, K., Sugawara, S., Oizumi, S., Isobe, H., Gemma, A., Harada, M., Yoshizawa, H., Kinoshita, I., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0909530 · Cited by 5,525
Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer
Rosell, R., Moran, T., Queralt, C., Porta, R., Cardenal, F., Camps, C., Majem, M., Lopez-Vivanco, G., Isla, D., Provencio, M., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0904554 · Cited by 2,373
Jackman, D., Pao, W., Riely, G. J., Engelman, J. A., Kris, M. G., Jänne, P. A., Lynch, T., Johnson, B. E., & Miller, V. A. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.24.7049 · Cited by 793
Jackman, D. M., Holmes, A. J., Lindeman, N., Wen, P. Y., Kesari, S., Borras, A. M., Bailey, C., de Jong, F., Jänne, P. A., & Johnson, B. E. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2006.06.6126 · Cited by 260
Clarke, J. L., Pao, W., Wu, N., Miller, V. A., & Lassman, A. B. (2010) · Journal of Neuro-Oncology · doi:10.1007/s11060-010-0128-6 · Cited by 214
Cited by
Novello, S., Barlesi, F., Califano, R., Cufer, T., Ekman, S., Levra, M. G., Kerr, K., Popat, S., Reck, M., Senan, S., et al. (2016) · Annals of Oncology · doi:10.1093/annonc/mdw326 · Cited by 2,631
Planchard, D., Popat, S., Kerr, K., Novello, S., Smit, E. F., Faivre-Finn, C., Mok, T. S., Reck, M., Van Schil, P. E., Hellmann, M. D., et al. (2018) · Annals of Oncology · doi:10.1093/annonc/mdy275 · Cited by 2,274
Brigatinib versus Crizotinib in ALK -Positive Non–Small-Cell Lung Cancer
Camidge, D. R., Kim, H. R., Ahn, M.-J., Yang, J. C.-H., Han, J.-Y., Lee, J.-S., Hochmair, M. J., Li, J. Y.-C., Chang, G.-C., Lee, K. H., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1810171 · Cited by 980
Hida, T., Nokihara, H., Kondo, M., Kim, Y. H., Azuma, K., Seto, T., Takiguchi, Y., Nishio, M., Yoshioka, H., Imamura, F., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)30565-2 · Cited by 911
Acquired resistance to TKIs in solid tumours: learning from lung cancer
Camidge, D. R., Pao, W., & Sequist, L. V. (2014) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2014.104 · Cited by 862
Metadata
- Authors
- Costa, D. B., Kobayashi, S., Pandya, S. S., Yeo, W.-L., Shen, Z., Tan, W., & Wilner, K. D.
- Venue
- Journal of Clinical Oncology
- Published
- 2011-05-20
- Volume
- 29
- Issue
- 15
- Pages
- e443-e445
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W2147038864
- Cited by
- 596
- References
- 6
- FWCI
- 26.97
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Costa, D. B., Kobayashi, S., Pandya, S. S., Yeo, W.-L., Shen, Z., Tan, W., & Wilner, K. D. (2011). CSF Concentration of the Anaplastic Lymphoma Kinase Inhibitor Crizotinib. Journal of Clinical Oncology. https://doi.org/10.1200/jco.2010.34.1313
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