Immersive Virtual Reality for Reducing Experimental Ischemic Pain
Abstract
This study explored the novel use of immersive virtual environments as a nonpharmacologic pain control technique and whether it works for both men and women. Fourteen female and 8 male students underwent pain induced via a blood pressure cuff ischemia lasting 10 min or less. Pain ratings increased significantly every 2 min during the no distraction phase (0 to 8 min) and dropped dramatically during the last 2 min period when participants were in the virtual environment (a 59% drop for women and a 41% drop for men). Five visual analog pain scores for each treatment condition served as the primary dependent variables. All 22 participants reported a drop in pain in the virtual environment, and the magnitude of pain reduction from the virtual environment was large (a 52% drop) and statistically significant. This is the first study to show immersive virtual environment distraction is also effective for women. The results show that virtual environments can function as a strong nonpharmacologic pain reduction technique, showing the same pattern of results obtained from recent clinical studies using virtual environments with burn patients during physical therapy. Practical applications of virtual environment pain reduction, and the value of a multidisciplinary approach to studying pain are discussed.
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Virtual Reality uses up a lot of attentional resources.
“Virtual Reality uses up a lot of attentional resources [21]”
Cites
(1963) · Medical Entomology and Zoology · Cited by 15,085 · see citing works
Pain mechanisms: a new theory.
Melzack, R., & Wall, P. D. (1965) · Science · doi:10.1126/science.150.3699.971 · Cited by 11,108 · see citing works
The American Journal of Physiology
(1899) · The American Naturalist · doi:10.1086/277182 · Cited by 5,680 · see citing works
Engineering Psychology and Human Performance
Wickens, C. D., Hollands, J. G., Banbury, S. P., & Parasuraman, R. (2015) · Psychology Press eBooks · doi:10.4324/9781315665177 · Cited by 4,998 · see citing works
HUSKISSON, E. C. (1974) · The Lancet · doi:10.1016/s0140-6736(74)90884-8 · Cited by 4,533 · see citing works
Melzack, R., & Wall, P. D. (1996) · Pain Forum · doi:10.1016/s1082-3174(96)80062-6 · Cited by 2,786 · see citing works
Rheingold, H. (1991) · Cited by 1,804 · see citing works
Visual analogue scales: measurement of subjective phenomena.
Gift, A. G. (1989) · PubMed · Cited by 1,138 · see citing works
The effects of divided attention on encoding and retrieval processes in human memory.
Craik, F. I. M., Govoni, R., Naveh-Benjamin, M., & Anderson, N. D. (1996) · Journal of Experimental Psychology: General · doi:10.1037/0096-3445.125.2.159 · Cited by 1,024 · see citing works
Neural Blockade in Clinical Anesthesia and Management of Pain
Cousins, M. J., Bridenbaugh, P. O., & Lippincott, P. J. B. (1981) · Anesthesiology · doi:10.1097/00000542-198110000-00046 · Cited by 825 · see citing works
Separating conscious and unconscious influences of memory: Measuring recollection.
Jacoby, L. L., Toth, J. P., & Yonelinas, A. P. (1993) · Journal of Experimental Psychology General · doi:10.1037/0096-3445.122.2.139 · Cited by 802 · see citing works
Distraction and coping with pain.
McCaul, K. D., & Malott, J. M. (1984) · Psychological Bulletin · doi:10.1037/0033-2909.95.3.516 · Cited by 713 · see citing works
Virtual reality as an adjunctive pain control during burn wound care in adolescent patients
Hoffman, H. G., Doctor, J. N., Patterson, D. R., Carrougher, G. J., & Furness, T. A. (2000) · Pain · doi:10.1016/s0304-3959(99)00275-4 · Cited by 651 · see citing works
Self-citationHypnosis In The Relief Of Pain
Hilgard, E. R., & Hilgard, J. R. (2013) · Routledge eBooks · doi:10.4324/9780203765647 · Cited by 638 · see citing works
Jacoby, L. L., Woloshyn, V. E., & Kelley, C. (1989) · Journal of Experimental Psychology General · doi:10.1037/0096-3445.118.2.115 · Cited by 591 · see citing works
Ratio scales of sensory and affective verbal pain descriptors
Gracely, R. H., McGrath, P., & Dubner, R. (1978) · Pain · doi:10.1016/0304-3959(78)90020-9 · Cited by 553 · see citing works
Virtual reality in the treatment of spider phobia: a controlled study
Garcia-Palacios, A., Hoffman, H., Carlin, A., Furness, T. A., & Botella, C. (2002) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(01)00068-7 · Cited by 490 · see citing works
Self-citationIkemura, K. (1971) · Journal of Japan Institute of Light Metals · doi:10.2464/jilm.21.771 · Cited by 446 · see citing works
Virtual reality and tactile augmentation in the treatment of spider phobia: a case report
Carlin, A. S., Hoffman, H. G., & Weghorst, S. J. (1997) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(96)00085-x · Cited by 442 · see citing works
Self-citationHoffman, H. G., Patterson, D. R., & Carrougher, G. J. (2000) · Clinical Journal of Pain · doi:10.1097/00002508-200009000-00010 · Cited by 431 · see citing works
Self-citationMelzack, R. (1990) · Scientific American · doi:10.1038/scientificamerican0290-27 · Cited by 429 · see citing works
Effectiveness of Virtual Reality–Based Pain Control With Multiple Treatments
Hoffman, H. G., Patterson, D. R., Carrougher, G. J., & Sharar, S. R. (2001) · Clinical Journal of Pain · doi:10.1097/00002508-200109000-00007 · Cited by 360 · see citing works
Self-citationThe Event-Related Brain Potential as an Index of Display-Monitoring Workload
Isreal, J. B., Wickens, C. D., Chesney, G. L., & Donchin, E. (1980) · Human Factors The Journal of the Human Factors and Ergonomics Society · doi:10.1177/001872088002200210 · Cited by 309 · see citing works
Anderson, N. D., Craik, F. I. M., & Naveh‐Benjamin, M. (1998) · Psychology and Aging · doi:10.1037//0882-7974.13.3.405 · Cited by 296 · see citing works
The utility of cognitive coping strategies for altering pain perception: a meta-analysis
Fernandez, E., & Turk, D. C. (1989) · Pain · doi:10.1016/0304-3959(89)90230-3 · Cited by 290 · see citing works
Hoffman, H. G. (2002) · IEEE Conference on Virtual Reality and 3D User Interfaces (VR) · doi:10.1109/vrais.1998.658423 · Cited by 233 · see citing works
Self-citationThe Effectiveness of Virtual Reality for Dental Pain Control: A Case Study
Hoffman, H. G., García‐Palacios, A., Patterson, D. R., Jensen, M. P., Furness, T. A., & Ammons, W. F. (2001) · CyberPsychology & Behavior · doi:10.1089/109493101750527088 · Cited by 219 · see citing works
Self-citationCohen, L. L., Blount, R. L., & Panopoulos, G. (1997) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/22.3.355 · Cited by 219 · see citing works
Cognitive and cognitive-behavioral methods for pain control: A selective review
Tan, S. (1982) · Pain · doi:10.1016/0304-3959(82)90154-3 · Cited by 207 · see citing works
Ischemic but Not Thermal Pain Sensitivity Varies Across the Menstrual Cycle
Fillingim, R. B., Maixner, W. D., Girdler, S. S., Light, K. C., Harris, M. B., Sheps, D. S., & Mason, G. (1997) · Psychosomatic Medicine · doi:10.1097/00006842-199709000-00008 · Cited by 197 · see citing works
Profile Analysis of Simulator Sickness Symptoms: Application to Virtual Environment Systems
Kennedy, R. S., Lane, N. E., Lilienthal, M. G., Berbaum, K. S., & Hettinger, L. J. (1992) · PRESENCE Virtual and Augmented Reality · doi:10.1162/pres.1992.1.3.295 · Cited by 168 · see citing works
A Distraction Technique for Control of Burn Pain
Miller, A. C., Hickman, L. C., & LeMasters, G. K. (1992) · Journal of Burn Care & Rehabilitation · doi:10.1097/00004630-199209000-00012 · Cited by 148 · see citing works
Humor as a cognitive technique for increasing pain tolerance
Weisenberg, M., Tepper, I., & Schwarzwald, J. (1995) · Pain · doi:10.1016/0304-3959(95)00046-u · Cited by 147 · see citing works
Hypnosis for the treatment of burn pain.
Patterson, D. R., Everett, J. J., Burns, G. L., & Marvin, J. A. (1992) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.60.5.713 · Cited by 146 · see citing works
Interfaces that heal: coupling real and virtual objects to treat spider phobia
Hoffman, H. G., Garcia-Palacios, A., Carlin, A., Furness III, T. A., & Botella-Arbona, C. (2003) · International Journal of Human-Computer Interaction · doi:10.1207/s15327590ijhc1602_08 · Cited by 144 · see citing works
Self-citationPhysically touching and tasting virtual objects enhances the realism of virtual experiences
Hoffman, H. G., Hollander, A., Schroder, K. E., Rousseau, S., & Furness, T. A. (1998) · Virtual Reality · doi:10.1007/bf01408703 · Cited by 122 · see citing works
Self-citationAssessment of Pain by Burn Patients
Perry, S. W., Heidrich, G., & Ramos, E. (1981) · Journal of Burn Care & Rehabilitation · doi:10.1097/00004630-198111000-00004 · Cited by 118 · see citing works
Gender Differences in Pain and Cardiovascular Responses to Forearm Ischemia
Maixner, W. D., & Humphrey, C. (1993) · Clinical Journal of Pain · doi:10.1097/00002508-199303000-00003 · Cited by 111 · see citing works
Proceedings of the 8th World Congress on Pain
Svensson, P., Johannsen, P., Jensen, T. E., Arendt‐Nielsen, L., Nielsen, J., Stødkilde‐Jørgensen, H., Gee, A. D., Hansen, S. B., & Gjedde, A. (1997) · Cited by 110 · see citing works
Presence in virtual environments as a function of visual and auditory cues
Hendrix, C. M., & Barfield, W. (2002) · doi:10.1109/vrais.1995.512482 · Cited by 107 · see citing works
Segerdahl, M., Ekblom, A., & Sollevi, A. (1994) · Anesthesia & Analgesia · doi:10.1213/00000539-199410000-00029 · Cited by 97 · see citing works
Cardiovascular and sensory responses to forearm ischemia and dynamic hand exercise
Maixner, W. D., Gracely, R. H., Zuniga, J. R., Humphrey, C., & Bloodworth, G. R. (1990) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1990.259.6.r1156 · Cited by 87 · see citing works
Lorenz, J., & Bromm, B. (1997) · Psychophysiology · doi:10.1111/j.1469-8986.1997.tb02387.x · Cited by 86 · see citing works
Pain, coping, and adjustment in patients with burns: Preliminary findings from a prospective study
Ptacek, J. T., Patterson, D. R., Montgomery, B. K., & Heimbach, D. M. (1995) · Journal of Pain and Symptom Management · doi:10.1016/0885-3924(95)00083-b · Cited by 84 · see citing works
Distraction and coping with pain.
McCaul, K. D., & Malott, J. M. (1984) · Psychological Bulletin · doi:10.1037//0033-2909.95.3.516 · Cited by 82 · see citing works
Virtual Chess: Meaning Enhances Users' Sense of Presence in Virtual Environments
Hoffman, H. G., Prothero, J. D., Wells, M. J., & Groen, J. (1998) · International Journal of Human-Computer Interaction · doi:10.1207/s15327590ijhc1003_3 · Cited by 81 · see citing works
Self-citationSuggestion and distraction in the control of pain: Test of two hypotheses.
Farthing, G. W., Venturino, M., & Brown, S. W. (1984) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.93.3.266 · Cited by 79 · see citing works
The attentional demands of encoding and retrieval in younger and older adults
Anderson, N. D. (1997) · Library and Archives Canada (Government of Canada) · Cited by 77 · see citing works
Hoffman, H. G., Patterson, D. R., Carrougher, G. J., Nakamura, D. Y., Moore, M. L., García‐Palacios, A., & Furness, T. A. (2001) · International Journal of Human-Computer Interaction · doi:10.1207/s15327590ijhc1301_1 · Cited by 73 · see citing works
Self-citationPractical Applications of Psychological Techniques in Controlling Burn Pain
Patterson, D. R. (1992) · Journal of Burn Care & Rehabilitation · doi:10.1097/00004630-199201000-00005 · Cited by 72 · see citing works
Comparison of patient satisfaction and self-reports of pain in adult burn-injured patients.
Carrougher, G., Ptacek, J., Sharar, S., Wiechman, S., Honari, S., Patterson, D., & Heimbach, D. (2003) · Journal of Burn Care and Rehabilitation · doi:10.1097/00004630-200301000-00003 · Cited by 62 · see citing works
Non-Opioid-Based Approaches to Burn Pain
Patterson, D. R. (1995) · Journal of Burn Care & Rehabilitation · doi:10.1097/00004630-199505001-00007 · Cited by 62 · see citing works
Slifer, K. J. (1996) · Journal of Pediatric Oncology Nursing · doi:10.1177/104345429601300208 · Cited by 61 · see citing works
The Quota System in Burn Rehabilitation
Ehde, D. M., Patterson, D. R., & Fordyce, W. E. (1998) · Journal of Burn Care & Rehabilitation · doi:10.1097/00004630-199809000-00014 · Cited by 39 · see citing works
Jacoby, L. L., Woloshyn, V. E., & Kelley, C. (1989) · Journal of Experimental Psychology General · doi:10.1037//0096-3445.118.2.115 · Cited by 34 · see citing works
Kozarek, R. A., Raltz, S. L., NEAL, L., WILBUR, P., STEWART, S., & RAGSDALE, J. A. (1997) · Gastroenterology Nursing · doi:10.1097/00001610-199701000-00004 · Cited by 19 · see citing works
Three Decades of Pain Research and its Control
Dubner, R. A. (1997) · Journal of Dental Research · doi:10.1177/00220345970760030401 · Cited by 11 · see citing works
Experimentally induced ischemic pain and so-called diaphase fix current
Hämäläinen, O., & Kemppainen, P. (2020) · Journal of Rehabilitation Medicine · doi:10.2340/1650197790222527 · Cited by 9 · see citing works
Slifer, K. J. (1996) · Journal of Pediatric Oncology Nursing · doi:10.1016/s1043-4542(96)90061-2 · Cited by 8 · see citing works
Flagged first, then by citations
2 of the 61 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
The effectiveness of virtual reality distraction for pain reduction: A systematic review
Malloy, K. M., & Milling, L. S. (2010) · Clinical Psychology Review · doi:10.1016/j.cpr.2010.07.001 · Cited by 653 · see citing works
Hoffman, H. G., Chambers, G. T., Meyer, W. J., Arceneaux, L. L., Russell, W. J., Seibel, E. J., Richards, T. L., Sharar, S. R., & Patterson, D. R. (2011) · Annals of Behavioral Medicine · doi:10.1007/s12160-010-9248-7 · Cited by 599 · see citing works
Self-citationVirtual Reality and Pain Management: Current Trends and Future Directions
Li, A., Montaño, Z., Chen, V. J., & Gold, J. I. (2011) · Pain Management · doi:10.2217/pmt.10.15 · Cited by 542 · see citing works
Indovina, P., Barone, D., Gallo, L., Chirico, A., De Pietro, G., & Giordano, A. (2018) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000599 · Cited by 388 · see citing works
Virtual reality pain control during burn wound debridement in the hydrotank
Hoffman, H. G., Patterson, D. R., Seibel, E., Soltani, M., Jewett-Leahy, L., & Sharar, S. R. (2008) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e318164d2cc · Cited by 352 · see citing works
Self-citationHoffman, H. G., Richards, T. L., Van Oostrom, T., Coda, B. A., Jensen, M. P., Blough, D. K., & Sharar, S. R. (2007) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000270205.45146.db · Cited by 295 · see citing works
Self-citationManipulating presence influences the magnitude of virtual reality analgesia
Hoffman, H. G., Sharar, S. R., Coda, B. A., Everett, J. J., Ciol, M. A., Richards, T. L., & Patterson, D. R. (2004) · Pain · doi:10.1016/j.pain.2004.06.013 · Cited by 267 · see citing works
Self-citationThe Neurobiology of Virtual Reality Pain Attenuation
Gold, J. I., Belmont, K. A., & Thomas, D. A. (2007) · CyberPsychology & Behavior · doi:10.1089/cpb.2007.9993 · Cited by 266 · see citing works
Navarro-Haro, M. V., López-del-Hoyo, Y., Campos, D., Linehan, M. M., Hoffman, H. G., García-Palacios, A., Modrego-Alarcón, M., Borao, L., & García-Campayo, J. (2017) · PLoS ONE · doi:10.1371/journal.pone.0187777 · Cited by 262 · see citing works
“Virtual Reality uses up a lot of attentional resources [21], making it less likely that attention will drift to sights and sounds in the real world, and the increased sensory input may reduce distressing thoughts or emotions, while in VR.”
BackgroundSelf-citationVirtual Reality Helmet Display Quality Influences the Magnitude of Virtual Reality Analgesia
Hoffman, H. G., Seibel, E. J., Richards, T. L., Furness, T. A., Patterson, D. R., & Sharar, S. R. (2006) · Journal of Pain · doi:10.1016/j.jpain.2006.04.006 · Cited by 246 · see citing works
Self-citationSmith, V., Warty, R. R., Sursas, J. A., Payne, O., Nair, A., Krishnan, S., Costa, F. D. S., Wallace, E. M., & Vollenhoven, B. J. (2020) · Journal of Medical Internet Research · doi:10.2196/17980 · Cited by 236 · see citing works
Sharar, S. R., Carrougher, G. J., Nakamura, D. Y., Hoffman, H. G., Blough, D. K., & Patterson, D. R. (2007) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2007.09.004 · Cited by 224 · see citing works
Self-citationVirtual reality therapy for anxiety disorders: Advances in evaluation and treatment.
Wiederhold, B. K., & Wiederhold, M. D. (2005) · doi:10.1037/10858-000 · Cited by 199 · see citing works
Maani, C. V., Hoffman, H. G., Morrow, M., Maiers, A., Gaylord, K., McGhee, L. L., & DeSocio, P. A. (2011) · Journal of Trauma: Injury, Infection & Critical Care · doi:10.1097/ta.0b013e31822192e2 · Cited by 202 · see citing works
The use of virtual reality for pain control: A review
Mahrer, N. E., & Gold, J. I. (2009) · Current Pain and Headache Reports · doi:10.1007/s11916-009-0019-8 · Cited by 194 · see citing works
Hoffman, H. G., Meyer, W. J., Ramirez, M., Roberts, L., Seibel, E. J., Atzori, B., Sharar, S. R., & Patterson, D. R. (2014) · Cyberpsychology Behavior and Social Networking · doi:10.1089/cyber.2014.0058 · Cited by 175 · see citing works
Self-citationWismeijer, A. A. J., & Vingerhoets, A. J. J. M. (2005) · Annals of Behavioral Medicine · doi:10.1207/s15324796abm3003_11 · Cited by 175 · see citing works
Virtual Reality Distraction for Pain Control During Periodontal Scaling and Root Planing Procedures
Furman, E., Jasinevicius, T. R., Bissada, N. F., Victoroff, K. Z., Skillicorn, R., & Buchner, M. (2009) · The Journal of the American Dental Association · doi:10.14219/jada.archive.2009.0102 · Cited by 174 · see citing works
Hoffman, H. G., Rodriguez, R. A., Gonzalez, M., Bernardy, M. K., Peña, R., Beck, W., Patterson, D. R., & Meyer, W. J. (2019) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2019.00262 · Cited by 165 · see citing works
Self-citationExtended Reality (XR) Remote Research: a Survey of Drawbacks and Opportunities
Ratcliffe, J., Soave, F., Bryan–Kinns, N., Tokarchuk, L. N., & Farkhatdinov, I. (2021) · University of the Arts London Research Online (University of the Arts London) · Cited by 145 · see citing works
Introduction to Games-Based Learning
Tang, S., Hanneghan, M., & Rhalibi, A. E. (2009) · IGI Global eBooks · doi:10.4018/978-1-60566-360-9.ch001 · Cited by 141 · see citing works
Extended Reality (XR) Remote Research: a Survey of Drawbacks and Opportunities
Ratcliffe, J., Soave, F., Bryan-Kinns, N., Tokarchuk, L., & Farkhatdinov, I. (2021) · CHI Conference on Human Factors in Computing Systems · doi:10.1145/3411764.3445170 · Cited by 176 · see citing works
Sharar, S. R., Alamdari, A., Hoffer, C. J., Hoffman, H. G., Jensen, M. P., & Patterson, D. R. (2016) · Games for Health Journal · doi:10.1089/g4h.2015.0046 · Cited by 113 · see citing works
Self-citationThe Past, Present, and Future of Virtual Reality in Pharmacy Education
Coyne, L., Merritt, T. A., Parmentier, B. L., Sharpton, R. A., & Takemoto, J. K. (2019) · American Journal of Pharmaceutical Education · doi:10.5688/ajpe7456 · Cited by 113 · see citing works
Analgesic effects of posthypnotic suggestions and virtual reality distraction on thermal pain
Patterson, D. R., Hoffman, H. G., Palacios, A. G., & Jensen, M. J. (2006) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.115.4.834 · Cited by 100 · see citing works
Self-citationJahanishoorab, N., Zagami, S. E., Nahvi, A., Mazluom, S. R., Golmakani, N., Talebi, M., & Pabarja, F. (2015) · PubMed Central · Cited by 84 · see citing works
Leibovici, V., Magora, F., Cohen, S. E., & Ingber, A. (2009) · Pain Research and Management · doi:10.1155/2009/178751 · Cited by 82 · see citing works
Hoffman, H. G. (2021) · Scientific Reports · doi:10.1038/s41598-021-89526-4 · Cited by 67 · see citing works
Self-citationThe Impact of Flow Experience and Personality Type on the Intention to Use Virtual World
Ahmad, N., & Abdulkarim, H. (2018) · International Journal of Human-Computer Interaction · doi:10.1080/10447318.2018.1509500 · Cited by 65 · see citing works
Gold, J. I., Kant, A. J., Kim, S. H., & Rizzo, A. (2005) · Seminars in Anesthesia Perioperative Medicine and Pain · doi:10.1053/j.sane.2005.10.005 · Cited by 63 · see citing works
Use of Virtual Reality Feedback for Patients with Chronic Neck Pain and Kinesiophobia
Chen, K., Sesto, M. E., Ponto, K., Leonard, J. W., Mason, A. H., Vanderheiden, G. C., Williams, J., & Radwin, R. G. (2016) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2016.2621886 · Cited by 61 · see citing works
Catastrophizing delays the analgesic effect of distraction
Campbell, C. M., Witmer, K., Simango, M., Carteret, A. F., Loggia, M. L., Campbell, J. N., Haythornthwaite, J. A., & Edwards, R. R. (2010) · Pain · doi:10.1016/j.pain.2009.11.012 · Cited by 59 · see citing works
Virtual reality immersion method of distraction to control experimental ischemic pain.
Magora, F., Cohen, S. E., Shochina, M., & Dayan, E. (2006) · PubMed · Cited by 53 · see citing works
Virtual Reality as a Tool for Cognitive Behavioral Therapy: A Review
Scozzari, S., & Gamberini, L. (2011) · Studies in computational intelligence · doi:10.1007/978-3-642-17824-5_5 · Cited by 52 · see citing works
What are the psychiatric sequelae of burn pain?
Askay, S. W., & Patterson, D. R. (2008) · Current Pain and Headache Reports · doi:10.1007/s11916-008-0018-1 · Cited by 48 · see citing works
Alghamdi, N., Meyer, W. J., Atzori, B., Alhalabi, W., Seibel, C. C., Ullman, D., & Hoffman, H. G. (2020) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2019.00467 · Cited by 47 · see citing works
Self-citationKaya, M., & Özlü, Z. K. (2022) · Burns · doi:10.1016/j.burns.2022.06.001 · Cited by 46 · see citing works
Maani, C. V., Hoffman, H. G., Fowler, M., Maiers, A. J., Gaylord, K. M., & DeSocio, P. A. (2011) · Pain Medicine · doi:10.1111/j.1526-4637.2011.01091.x · Cited by 45 · see citing works
Self-citationWilson, K., & Scorsone, G. (2021) · Frontiers in Virtual Reality · doi:10.3389/frvir.2021.695449 · Cited by 40 · see citing works
Hadjiat, Y., & Marchand, S. (2022) · Frontiers in Pain Research · doi:10.3389/fpain.2022.840921 · Cited by 40 · see citing works
The feasibility of a mixed reality surgical training environment
Moody, L., Waterworth, A., McCarthy, A. D., Harley, P. J., & Smallwood, R. H. (2007) · Virtual Reality · doi:10.1007/s10055-007-0080-8 · Cited by 32 · see citing works
Optimizing Control of Pain from Severe Burns: A Literature Review
Patterson, D. R., Hoffman, H. G., Weichman, S. A., Jensen, M. P., & Sharar, S. R. (2004) · American Journal of Clinical Hypnosis · doi:10.1080/00029157.2004.10401474 · Cited by 29 · see citing works
Self-citationHoffman, H. G., Fontenot, M. R., García‐Palacios, A., Greenleaf, W. J., Alhalabi, W., Curatolo, M., & Flor, H. (2023) · Scientific Reports · doi:10.1038/s41598-023-31038-4 · Cited by 29 · see citing works
Self-citationVirtual reality in managing dental pain and anxiety: a comprehensive review
Fan, L., Zeng, J., Ran, L., Zhang, C., Wang, J., Yu, C., & Zhao, N. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1285142 · Cited by 31 · see citing works
Virtual Reality Distraction to Help Control Acute Pain during Medical Procedures
Hoffman, H. G., Meyer, W. J., Drever, S. A., Soltani, M., Atzori, B., Herrero, R., Alhalabi, W., Richards, T. L., Sharar, S. R., Jensen, M. P., et al. (2019) · Virtual reality technologies for health and clinical applications · doi:10.1007/978-1-4939-9482-3_8 · Cited by 28 · see citing works
Self-citationMobile virtual reality distraction reduces needle pain and stress in children?
Piskorz, J., Czub, M., Šulžickaja, B., & Kiliś‐Pstrusińska, K. (2020) · Cyberpsychology Journal of Psychosocial Research on Cyberspace · doi:10.5817/cp2020-1-3 · Cited by 26 · see citing works
Virtual reality in the treatment of pain
Botella, C., Díaz‐García, A., Baños, R., Quero, S., & Bretón, J. M. (2008) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 24 · see citing works
Liszio, S., Basu, O., & Masuch, M. (2020) · Annual Symposium on Computer-Human Interaction in Play · doi:10.1145/3410404.3414263 · Cited by 21 · see citing works
Demeter, N., Josman, N., Eisenberg, E., & Pud, D. (2015) · European Journal of Pain · doi:10.1002/ejp.678 · Cited by 21 · see citing works
Lier, E. J., Harder, J., Oosterman, J. M., de Vries, M., & van Goor, H. (2018) · PLoS ONE · doi:10.1371/journal.pone.0208405 · Cited by 21 · see citing works
Momenyan, N., Safaei, A., & Hantoushzadeh, S. (2021) · Clinical and Experimental Obstetrics & Gynecology · doi:10.31083/j.ceog.2021.01.2116 · Cited by 19 · see citing works
Influence of altered visual feedback on neck movement for a virtual reality rehabilitative system
Chen, K., Ponto, K., Sesto, M. E., & Radwin, R. G. (2014) · Proceedings of the Human Factors and Ergonomics Society Annual Meeting · doi:10.1177/1541931214581162 · Cited by 15 · see citing works
Virtual reality for gait rehabilitation - promises, proofs and preferences
Powell, W. A., Powell, V., & Simmonds, M. J. (2014) · International Conference on PErvasive Technologies Related to Assistive Environments (PETRA) · doi:10.1145/2674396.2674450 · Cited by 14 · see citing works
Effects of Virtual Reality during Exercise in Children
Cebolla, A., Botella, C., Lurbe, E., Guixeres, J., Sáiz, J., Lisón, J. F., Álvarez‐Pitti, J., Cantero, L., Alcañíz, M., Escobar, P., et al. (2020) · Repositori UJI (Universitat Jaume I) · doi:10.3217/jucs-019-09-1199 · Cited by 14 · see citing works
Therapy-led design of home-based virtual rehabilitation
Powell, V., & Powell, W. A. (2015) · IEEE Workshop on Everyday Virtual Reality (WEVR) · doi:10.1109/wevr.2015.7151688 · Cited by 13 · see citing works
Powell, W. A., & Stevens, B. (2013) · International Conference on Virtual Rehabilitation · doi:10.1109/icvr.2013.6662085 · Cited by 12 · see citing works
Gomez, A. M., Hill, C., Lin, H. Y., Fotouhi, J., Han-Oh, S., Wang, K. K.-H., Navab, N., & Narang, A. K. (2020) · Computer Methods in Biomechanics and Biomedical Engineering Imaging & Visualization · doi:10.1080/21681163.2020.1835547 · Cited by 11 · see citing works
EMMA: An Adaptive Display for Virtual Therapy
Alcañíz, M., Botella, C., Solaz, B. R., Baños, R., Lozano, J. A., de la Vega, N. L., Castilla, D., Montesa, J., & Hospitaler, A. (2007) · Lecture notes in computer science · doi:10.1007/978-3-540-73216-7_29 · Cited by 11 · see citing works
Hoffman, H. G., Seibel, C. C., Coron, L., Simons, L. E., Drever, S. A., May, S. L., Mason, K. P., & Flor, H. (2024) · Frontiers in Virtual Reality · doi:10.3389/frvir.2024.1452486 · Cited by 10 · see citing works
Self-citationPowell, W. A., & Simmonds, M. J. (2014) · Cyberpsychology Behavior and Social Networking · doi:10.1089/cyber.2014.0061 · Cited by 9 · see citing works
Active Virtual Reality Games Reduce Pain Sensitivity in Young, Healthy Adults
Evans, E. J., Naugle, K. E., Ovispo, A., Kaleth, A. S., Arnold, B. L., & Naugle, K. M. (2021) · Frontiers in Virtual Reality · doi:10.3389/frvir.2021.772293 · Cited by 7 · see citing works
Demeter, N., Pud, D., & Josman, N. (2018) · Frontiers in Robotics and AI · doi:10.3389/frobt.2017.00070 · Cited by 6 · see citing works
Electrical Muscle Stimulation to Develop and Implement Menstrual Simulator System
Asada, C., Tsutsumi, K., Tamura, Y., Hara, N., Omori, W., Otsuka, Y., & Sato, K. (2021) · Journal of Robotics and Mechatronics · doi:10.20965/jrm.2021.p1051 · Cited by 6 · see citing works
Aboushady, R. M. N., Soliman, H. F. A., Amr, T. E.-S. E.-S., & Elnabi, M. M. E. A. (2023) · Egyptian Journal of Health Care · doi:10.21608/ejhc.2023.295784 · Cited by 5 · see citing works
EFFECTIVENESS OF DIFFERENT VIRTUAL REALITY ENVIRONMENTS ON THERMAL PAIN DISTRACTION
Czub, M., & Piskorz, J. (2012) · Polish Journal of Applied Psychology · Cited by 5 · see citing works
Demirci, H., Lachkar, T., Fleur, W. X. I., Barsom, E. Z., Eskes, A. M., & Schijven, M. P. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e40858 · Cited by 6 · see citing works
Powell, W. A. (2011) · UPT. Syiah Kuala University Library (Syiah Kuala University) · Cited by 4 · see citing works
Powell, V., & Powell, W. A. (2014) · Cited by 3 · see citing works
Extended Reality in Patient Care and Pharmacy Practice: A Viewpoint
Takemoto, J. K., Parmentier, B. L., Bratelli, R., & Merritt, T. A. (2020) · Journal of Contemporary Pharmacy Practice · doi:10.37901/jcphp18-00030 · Cited by 3 · see citing works
Ratcliffe, J., & Tokarchuk, L. N. (2022) · Frontiers in Computer Science · doi:10.3389/fcomp.2022.952996 · Cited by 3 · see citing works
Medical interface research at the HIT Lab
Weghorst, S. J., Seibel, E. J., Oppenheimer, P., Hoffman, H. G., Schowengerdt, B. T., & Furness, T. A. (2008) · Virtual Reality · doi:10.1007/s10055-008-0107-9 · Cited by 3 · see citing works
Self-citationExtended Reality in Patient Care and Pharmacy Practice: A Viewpoint
Takemoto, J. K., Parmentier, B. L., Bratelli, R., Merritt, T. A., & Coyne, L. (2019) · Journal of Contemporary Pharmacy Practice · doi:10.37901/2573-2765-66.4.33 · Cited by 2 · see citing works
The acute hypoalgesic effects of active head-mounted display virtual reality games
Naugle, K. E., Cervantes, X. A., Boone, C. L., Wind, B., & Naugle, K. M. (2024) · PLoS ONE · doi:10.1371/journal.pone.0308064 · Cited by 2 · see citing works
Considerations for virtual environments for upper limb rehabilitation tasks
Powell, V., Powell, W. A., & Simmonds, M. J. (2014) · International Conference on PErvasive Technologies Related to Assistive Environments (PETRA) · doi:10.1145/2674396.2674451 · Cited by 2 · see citing works
Transcutaneous electrical nerve stimulation based pain control system via Q-EEG validation
Panavaranan, P., & Wongsawat, Y. (2014) · Biomedical Engineering International Conference · doi:10.1109/bmeicon.2014.7017431 · Cited by 2 · see citing works
Virtual Reality Therapy for Acute/Procedural Pain
Frey, D. P., & Sharar, S. R. (2018) · Springer eBooks · doi:10.1007/978-3-319-95369-4_29 · Cited by 2 · see citing works
Virtual Reality Distraction Analgesia
Sharar, S. R. (2006) · Cited by 2 · see citing works
Pentangelo, V., Gravino, C., & Palomba, F. (2026) · Virtual Reality · doi:10.1007/s10055-026-01340-3 · Cited by 1 · see citing works
Im, J.-B., Hong, R.-L., Joo, M., Zhang, E., & Kim, J.-H. (2025) · Architectural Science Review · doi:10.1080/00038628.2025.2584180 · Cited by 1 · see citing works
Enhancing Mindfulness Training in Virtual Reality: A Randomized Trial of Biofeedback Integration
Domingues, A., Beato, A. F., Oliveira, J., & Gamito, P. S. (2025) · Cyberpsychology Behavior and Social Networking · doi:10.1177/21522715251397933 · Cited by 1 · see citing works
Emrich, M., McAleavey, A. A., Wyka, K., Greenway, A., Houng, A., Chang, P., Zhou, C. Q., & Difede, J. (2026) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-026-10146-z · Cited by 1 · see citing works
Kasai, R., Itoh, N., Kamijo, F., Kano, T., Shimamine, T., Ogino, M., Hinata, N., Tanaka, K., Shinohara, K., & Mizuno‐Matsumoto, Y. (2020) · Electronics and Communications in Japan · doi:10.1002/ecj.12289 · Cited by 1 · see citing works
A Systematic Review of Studies on Virtual Reality Use in Management of Pain
Eze, U. I. H., Adeyi, A. O., Ojieabu, W., & Eze, M. S. C. (2022) · Nigerian Journal of Pharmaceutical Research · doi:10.4314/njpr.v17i2.1 · Cited by 1 · see citing works
The effects of serious gaming on pain and fear of movement in patients with chronic low back pain
Van Hove, J., & Wolters, P. (2016) · Document Server@UHasselt (UHasselt)
Virtual Reality: An Emerging Tool to Treat Pain
Belard, J., Hoffman, H. G., Shore, J. H., Gaylord, K. M., & Maani, C. V. (2010)
Self-citationThe influence of virtual reality exposure on social and phobic behaviours
Oing, T. (2019) · UBIR (University of Greater Manchester)
Kasai, R., Itoh, N., Kamijo, F., Kano, T., Shimamine, T., Ogino, M., Hinata, N., Tanaka, K., Shinohara, K., & Mizuno‐Matsumoto, Y. (2020) · IEEJ Transactions on Electronics Information and Systems · doi:10.1541/ieejeiss.140.979
Hoffman, H. G. (2021) · Research Square · doi:10.21203/rs.3.rs-145582/v1
Self-citationArmstrong, M., Williams, H., Faith, E. F., Ni, A., & Xiang, H. (2026) · JMIR Research Protocols · doi:10.2196/87207
Armstrong, M., Williams, H., Faith, E. F., Ni, A., & Xiang, H. (2026) · medRxiv · doi:10.64898/2026.04.21.26351381
Sebastien, J., Zhu, J., Chirico, A., Mancuso, V., MARKS, A., Soffer, G., & Won, A. S. (2026) · Augmented Humans International Conference (AHs) · doi:10.1145/3795011.3795032
- Authors
- Hoffman, H. G., Garcia-Palacios, A., Kapa, V., Beecher, J., & Sharar, S. R.
- Affiliations
- University of Washington (US)
- Venue
- International Journal of Human-Computer Interaction
- Publisher
- Informa UK Limited
- Published
- 2003-06
- Volume
- 15
- Issue
- 3
- Pages
- 469-486
- ISSN
- 1044-7318 (ISSN-L)
- 1532-7590
- OpenAlex
- W1976683074
- Cited by
- 93
- References
- 61
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 9 · 2020: 9 · 2019: 5 · 2018: 5 · 2017: 1 · 2016: 3 · 2015: 3 · 2014: 7 · 2013: 1 · 2012: 1
- FWCI
- 4.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Human-Computer Interaction (publishedVersion)
- Topics
- Physical Sciences › Computer Science › Human-Computer Interaction › Virtual Reality Applications and Impacts
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- immersive virtual reality, ischemic pain, non-pharmacological pain management, analgesia, sex differences, pain perception, virtual reality therapy
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