The DOI matches its Crossref record; 175 of the 175 references it cites were found in a registry or an index.
Estrogen Receptors in Human Nontarget Tissues: Biological and Clinical Implications*
Abstract
THE idea to write this review began a number of years ago when one of us (D.R.C.) was working in Dr. William L. McGuire's laboratory in San Antonio, Texas,1 where we were involved in the study of estrogen receptor(s) (ER) and estrogen-regulated proteins in breast cancer. At that time ER were beginning to be identified in tissues not considered classic targets for estrogens. The idea of reviewing the literature on the presence of ER in nontarget tissues did not prosper because there were methodological problems that could give false positives for ER, such as those reported in melanomas (1). However, at that time ER could be detected by ligand binding assays. More than 10 yr have passed and the study of ER has been improved with the advent and widespread use of monoclonal antibodies against the receptor protein. The presence of ER has been described in numerous normal and pathological tissues using ligandbinding and immunochemical assays. In addition, ER have also been studied at the messenger RNA (mRNA) and DNA level. We can now explore whether the receptor is functional and whether it controls gene and cell functions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Simerly, R. B., Swanson, L. W., Chang, C., & Muramatsu, M. (1990) · Journal of Comparative Neurology · doi:10.1002/cne.902940107 · Cited by 2,118
Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6
Jilka, R. L., Hangoc, G., Girasole, G., Passeri, G., Williams, D. C., Abrams, J. S., Boyce, B., Broxmeyer, H., & Manolagas, S. C. (1992) · Science · doi:10.1126/science.1621100 · Cited by 1,442
Evidence of Estrogen Receptors in Normal Human Osteoblast-Like Cells
Eriksen, E. F., Colvard, D. S., Berg, N. J., Graham, M. L., Mann, K. G., Spelsberg, T. C., & Riggs, B. L. (1988) · Science · doi:10.1126/science.3388021 · Cited by 1,229
Knabbe, C., Lippman, M. E., Wakefield, L. M., Flanders, K. C., Kasid, A., Derynck, R., & Dickson, R. B. (1987) · Cell · doi:10.1016/0092-8674(87)90193-0 · Cited by 975
Estrogen Binding, Receptor mRNA, and Biologic Response in Osteoblast-Like Osteosarcoma Cells
Komm, B. S., Terpening, C. M., Benz, D. J., Graeme, K. A., Gallegos, A., Korc, M., Greene, G. L., O'Malley, B. W., & Haussler, M. R. (1988) · Science · doi:10.1126/science.3164526 · Cited by 812
Horwitz, K. B., & McGuire, W. L. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38062-6 · Cited by 799
Steroid Hormone Receptors: Interaction with Deoxyribonucleic Acid and Transcription Factors*
TRUSS, M., & BEATO, M. (1993) · Endocrine Reviews · doi:10.1210/edrv-14-4-459 · Cited by 741
Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line
Masiakowski, P., Breathnach, R., Bloch, J., Gannon, F., Krust, A., & Chambon, P. (1982) · Nucleic Acids Research · doi:10.1093/nar/10.24.7895 · Cited by 728
The Prolactin/Growth Hormone Receptor Family
KELLY, P. A., DJIANE, J., POSTEL-VINAY, M.-C., & EDERY, M. (1991) · Endocrine Reviews · doi:10.1210/edrv-12-3-235 · Cited by 727
Biological and Clinical Implications of Heat Shock Protein 27000 (Hsp27): a Review
Ciocca, D. R., Oesterreich, S., Chamness, G. C., MCGuire, W. L., & Fuqua, S. A. W. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.19.1558 · Cited by 542
Self-citation
Cited by
Molecular basis of agonism and antagonism in the oestrogen receptor
Brzozowski, A. M., Pike, A. C. W., Dauter, Z., Hubbard, R. E., Bonn, T., Engström, O., Öhman, L., Greene, G. L., Gustafsson, J.-Å., & Carlquist, M. (1997) · Nature · doi:10.1038/39645 · Cited by 3,355
Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?
Couse, J. F., & Korach, K. S. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0370 · Cited by 2,045
Mammary Gland Development and Tumorigenesis in Estrogen Receptor Knockout Mice
Bocchinfuso, W. P., & Korach, K. S. (1997) · Journal of Mammary Gland Biology and Neoplasia · doi:10.1023/a:1026339111278 · Cited by 362
Estrogen suppresses transcription of lipoprotein lipase gene
Homma, H., Kurachi, H., Nishio, Y., Takeda, T., Yamamoto, T., Adachi, K., Morishige, K.-I., Ohmichi, M., Matsuzawa, Y., & Murata, Y. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.15.11404 · Cited by 209
The Hair Follicle as an Estrogen Target and Source
Ohnemus, U., Uenalan, M., Inzunza, J., Gustafsson, J.-A., & Paus, R. (2006) · Endocrine Reviews · doi:10.1210/er.2006-0020 · Cited by 205
Metadata
- Authors
- CIOCCA, D. R., & VARGAS ROIG, L. M.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 1995-02
- Volume
- 16
- Issue
- 1
- Pages
- 35-62
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2008071275
- Cited by
- 260
- References
- 175
- FWCI
- 9.33
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Estrogen Receptors in Human Nontarget Tissues: Biological and Clinical Implications*. https://app.cochat.ai/papers/10.1210/edrv-16-1-35
- The paper
- CIOCCA, D. R., & VARGAS ROIG, L. M. (1995). Estrogen Receptors in Human Nontarget Tissues: Biological and Clinical Implications*. Endocrine Reviews. https://doi.org/10.1210/edrv-16-1-35
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
