Cited by 455Effects and risks of endocrine disrupting chemicalsEpigenetics and DNA MethylationSexual Differentiation and Disorders

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Epigenetic Transgenerational Actions of Endocrine Disruptors

Anway, Matthew D., Skinner, Michael K.·2006·Endocrinology

DOI 10.1210/en.2005-1058

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Abstract

Endocrine disruptors have recently been shown to promote an epigenetic transgenerational phenotype involving a number of disease states (e.g. male infertility). The anti-androgenic fungicide vinclozolin was found to act transiently at the time of embryonic sex determination to promote in the F1 generation a spermatogenic cell defect and subfertility in the male. When the animals were allowed to age up to 1 yr, a number of other disease states developed. This phenotype was transferred through the male germ line to all subsequent generations analyzed (F1-F4). The ability of an environmental factor (i.e. endocrine disruptor) to promote an epigenetic transgenerational phenotype impacts the potential hazards of environmental toxins, mechanisms of disease etiology, and evolutionary biology. The biological importance of the epigenetic actions of environmental agents is reviewed in the context of the primordial germ cell and development of epigenetic transgenerational phenotypes.

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DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
Okano, M., Bell, D. W., Haber, D. A., & Li, E. (1999) · Cell · doi:10.1016/s0092-8674(00)81656-6 · Cited by 6,143
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
Li, E., Bestor, T. H., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90611-f · Cited by 3,984
Epigenetic differences arise during the lifetime of monozygotic twins
Fraga, M. F., Ballestar, E., Paz, M. F., Ropero, S., Setien, F., Ballestar, M. L., Heine-Suñer, D., Cigudosa, J. C., Urioste, M., Benitez, J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500398102 · Cited by 3,602
Epigenetic Reprogramming in Mammalian Development
Reik, W., Dean, W., & Walter, J. (2001) · Science · doi:10.1126/science.1063443 · Cited by 3,078
Evidence for decreasing quality of semen during past 50 years.
Carlsen, E., Giwercman, A., Keiding, N., & Skakkebæk, N. E. (1992) · BMJ · doi:10.1136/bmj.305.6854.609 · Cited by 2,768
Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility
Anway, M. D., Cupp, A. S., Uzumcu, M., & Skinner, M. K. (2005) · Science · doi:10.1126/science.1108190 · Cited by 2,563
Self-citation
Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man
Smith, E. P., Boyd, J., Frank, G. R., Takahashi, H., Cohen, R. M., Specker, B., Williams, T. C., Lubahn, D. B., & Korach, K. S. (1994) · New England Journal of Medicine · doi:10.1056/nejm199410203311604 · Cited by 2,471
Genomic imprinting: parental influence on the genome
Reik, W., & Walter, J. (2001) · Nature Reviews Genetics · doi:10.1038/35047554 · Cited by 2,288
The Role of DNA Methylation in Mammalian Epigenetics
Jones, P. A., & Takai, D. (2001) · Science · doi:10.1126/science.1063852 · Cited by 2,125
Transposable elements: targets for early nutritional effects on epigenetic gene regulation
Waterland, R. A., & Jirtle, R. L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5293-5300.2003 · Cited by 2,019

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John, N., Rehman, H., Razak, S., David, M., Ullah, W., Afsar, T., Almajwal, A. M., Alam, I., & Jahan, S. (2019) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-019-0491-x · Cited by 28
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de Oliveira, S. R. L., Silva, I. C. B. D., Mariz, B. A. L. A., Pereira, A. M. B. C., & de Oliveira, N. F. P. (2015) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2015.02.022 · Cited by 27
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Tang, J., Fang, F., Miller, D. F., Pilrose, J. M., Matei, D. E., Huang, T. H. ‐., & Nephew, K. P. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1804-1_34 · Cited by 27
The Roles of Environment, Experience, and Learning in Behavioral Development
Michel, G. F. (2010) · Wiley eBooks · doi:10.1002/9781444327632.ch6 · Cited by 26
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Differential effects of p,p′-DDE on testis and liver mitochondria:Implications for reproductive toxicology
Mota, P. C., Cordeiro, M. H., Pereira, S. P., Oliveira, P. J., Moreno, A. J., & Ramalho‐Santos, J. (2010) · Reproductive Toxicology · doi:10.1016/j.reprotox.2010.09.010 · Cited by 25
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Li, X., Cao, S., Mao, B., Bai, Y., Chen, X., Wang, X., Wu, Y., Li, L., Lin, H., Lian, Q., et al. (2016) · Toxicology Mechanisms and Methods · doi:10.1080/15376516.2016.1202367 · Cited by 24
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James, P., Domínguez-Salas, P., Hennig, B. J., Moore, S. E., Prentice, A. M., & Silver, M. J. (2018) · Current Developments in Nutrition · doi:10.1093/cdn/nzy082 · Cited by 23
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(2014) · Elsevier eBooks · doi:10.1016/c2011-0-08000-6 · Cited by 25
Endocrine disruptors and obesity: Obesogens
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Bergeron, C. M., Hopkins, W. A., Jachowski, C. M. B., Budischak, S. A., Wada, H., & Unrine, J. M. (2011) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2011.07.036 · Cited by 23
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Price, T. M., Murphy, S. K., & Younglai, E. V. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfl196 · Cited by 21
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Liu, Y., Weyrich, L. S., & Llamas, B. (2019) · Molecular Biology and Evolution · doi:10.1093/molbev/msz231 · Cited by 21
Stanowisko Polskiego Towarzystwa Endokrynologicznego dotyczące związków endokrynnie czynnych (EDC)
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Isolation and characterization of three estrogen receptor transcripts in Oreochromis mossambicus (Peters)
Esterhuyse, M. M., Helbing, C. C., & van Wyk, J. H. (2009) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2009.12.002 · Cited by 17
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Pelch, K. E., Beeman, J. M., Niebruegge, B. A., Winkeler, S. R., & Nagel, S. C. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-374928-4.10014-8 · Cited by 16
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Impact of pesticide residues on fertility of dairy animals: A review
Ghuman, S. P. S., RATNAKARAN, U., Bedi, J. S., & Gill, J. P. S. (2013) · The Indian Journal of Animal Sciences · doi:10.56093/ijans.v83i12.35789 · Cited by 16
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Maguire, R. L., Vidal, A. C., Murphy, S. K., & Hoyo, C. (2016) · Advances in cancer research · doi:10.1016/bs.acr.2016.09.001 · Cited by 16
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Osborne, A. J., & Dearden, P. K. (2017) · Current Zoology · doi:10.1093/eep/dvx019 · Cited by 15
Evidence of intergenerational transmission of diethylstilbestrol health effects: hindsight and insight
Titus, L. J. (2021) · Biology of Reproduction · doi:10.1093/biolre/ioab153 · Cited by 15
Environmental Endocrine Disruption of Brain and Behavior
Gore, A. C., & Crews, D. P. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00056-5 · Cited by 15
Scientific consensus statement on environmental agents associated with neurodevelopmental disorders
Gilbert, S. G., & Miller, E. (2009) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2009.04.024 · Cited by 15
Few effects of multi-generational dietary exposure to genistein or nonylphenol on sodium solution intake in male and female Sprague–Dawley rats
Ferguson, S. A., Delclos, K. B., Newbold, R. R., & Flynn, K. (2009) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2009.01.009 · Cited by 15
Prenatal exposure to low doses of atrazine affects mating behaviors in male guppies
Shenoy, K. (2014) · Hormones and Behavior · doi:10.1016/j.yhbeh.2014.07.002 · Cited by 15
Prenatal Cocaine Exposure Alters BDNF-TrkB Signaling in the Embryonic and Adult Brain
McCarthy, D. M., Mueller, K. A., Cannon, E. N., Huizenga, M. N., Darnell, S. B., Bhide, P. G., & Sadri‐Vakili, G. (2016) · Developmental Neuroscience · doi:10.1159/000453609 · Cited by 14
Behavioral Epigenetics: Perspectives Based on Experience-Dependent Epigenetic Inheritance
Pang, Y.-Y., Lu, R. J.-H., & Chen, P. (2019) · Epigenomes · doi:10.3390/epigenomes3030018 · Cited by 18
Microbiome First Approaches to Rescue Public Health and Reduce Human Suffering
Dietert, R. R. (2021) · Biomedicines · doi:10.3390/biomedicines9111581 · Cited by 15
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BÖRSCH-HAUBOLD, A. G., Montero, I., Konrad, K., & Haubold, B. (2014) · PLoS ONE · doi:10.1371/journal.pone.0097568 · Cited by 16
Effects of vinclozolin, an anti-androgen, on affiliative behavior in the Dark-eyed Junco, Junco hyemalis
Satre, D., Reichert, M. S., & Corbitt, C. (2009) · Environmental Research · doi:10.1016/j.envres.2009.01.004 · Cited by 14
The Role of Environmental Obesogens in the Obesity Epidemic
Janesick, A., & Blumberg, B. (2010) · Endocrine updates · doi:10.1007/978-1-4419-7034-3_19 · Cited by 13
Nanoparticles as Potential Endocrine Disruptive Chemicals
Dagar, G., & Bagchi, G. (2020) · Springer eBooks · doi:10.1007/978-981-32-9898-9_17 · Cited by 14
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Wu, D., Feng, B., Dai, Y., Wu, X., Chen, B., Xu, C., Tang, Y., Wang, K., Zhang, S., Wang, S., et al. (2017) · EBioMedicine · doi:10.1016/j.ebiom.2017.02.006 · Cited by 12
Molecular mechanisms of mammary gland remodeling: A review of the homeostatic versus bisphenol a disrupted microenvironment
Ruiz, T. F. R., Taboga, S. R., & Leonel, E. C. R. (2021) · Reproductive Toxicology · doi:10.1016/j.reprotox.2021.07.011 · Cited by 12
Transgenerational epigenetics of endocrine-disrupting chemicals in mammals
Casati, L., & Celotti, F. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816363-4.00017-1 · Cited by 11
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Peinado, F. M., Iribarne-Durán, L. M., Hernández, O. O., Olea, N., & Artacho‐Cordón, F. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.93091 · Cited by 12
Multigenerational impacts of EE2 on reproductive fitness and immune competence of marine medaka
Peterson, D. R., Seemann, F., Wan, T., Ye, R., Chen, L., Lai, K. P., Yu, K. N., Kong, R. Y. C., & Au, D. W. T. (2023) · Aquatic Toxicology · doi:10.1016/j.aquatox.2023.106584 · Cited by 11
Environment and fetal programming: the origins of some current “pandemics”
Burgio, E. (2015) · Journal of pediatric and neonatal individualized medicine · doi:10.7363/040237 · Cited by 11
Infection before pregnancy affects immunity and response to social challenge in the next generation
Curno, O., Reader, T., McElligott, A. G., Behnke, J. M., & Barnard, C. J. (2011) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2011.0110 · Cited by 11
Effects of exogenous endocrine stimulation on epigenetic programming of the female germline genome.
de Waal, E., & McCarrey, J. R. (2010) · Animal Reproduction · Cited by 11
Endocrine Disruption
Evans, T. J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804239-7.00058-5 · Cited by 11
Life at the Interface Between a Dynamic Environment and a Fixed Genome: Epigenetic Programming of Stress Responses by Maternal Behavior
Weaver, I. C. G. (2009) · Humana Press eBooks · doi:10.1007/978-1-60761-287-2_2 · Cited by 11
Endocrine disruptors
Evans, T. J. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-382032-7.10067-0 · Cited by 11
The Future of Epigenetics: Emerging Technologies and Clinical Applications
Iyer, K. A., Tenchov, R., Sasso, J. M., Thite, T., Deng, Y., & Zhou, Q. A. (2026) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.5c00729 · Cited by 12
Influence of Climate Change & Environmental Toxicants on Epigenetic Modifications
Roy, S., Laha, I., Ray, D., & Choudhury, L. (2022) · World Journal of Environmental Biosciences · doi:10.51847/jku3edoakt · Cited by 10
Ancient Epigenomics
Hanghøj, K., & Orlando, L. (2018) · Population genomics · doi:10.1007/13836_2018_18 · Cited by 10
Safety of cannabis- and hemp-derived constituents in reproduction and development
Akingbasote, J. A., Szlapinski, S. K., Charrette, A., Hilmas, C. J., & Guthrie, N. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-89773-0.00024-2 · Cited by 10
Decentralization and recentralization: effects on the health systems in Lao PDR.
Phommasack, B., Oula, L., Khounthalivong, O., Keobounphanh, I., Misavadh, T., Loun, Oudomphone, P., Vongsamphanh, C., & Blas, E. (2005) · PubMed · Cited by 10
The metabolic responses of aquatic animal exposed to POPs
Zhou, H., Chen, C., & Diao, X. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818196-6.00005-4 · Cited by 10
Methodological Issues in Population-Based Studies of Multigenerational Associations
McGee, G., Perkins, N. J., Mumford, S. L., Kioumourtzoglou, M., Weisskopf, M. G., Schildcrout, J. S., Coull, B. A., Schisterman, E. F., & Haneuse, S. (2020) · American Journal of Epidemiology · doi:10.1093/aje/kwaa125 · Cited by 11
Paternal Epigenetic Inheritance
Rahia Mashoodh, A., & Champagne, F. A. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405944-3.00017-9 · Cited by 9
Epigenetics of Reproduction
McCarthy, M. M., & Rissman, E. F. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397175-3.00052-1 · Cited by 9
Smoking During Pregnancy and Risk of Attention-deficit/Hyperactivity Disorder in the Third Generation
Yim, G., Roberts, A., Ascherio, A., Wypij, D., Kioumourtzoglou, M.-A., & Weisskopf, A. M. G. (2022) · Epidemiology · doi:10.1097/ede.0000000000001467 · Cited by 9
Adipocytes as Target Cells for Endocrine Disruption
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Authors: Anway, M. D., & Skinner, M. K.
Affiliations: Washington State University (US)
Corresponding author: Skinner, Michael K.
ORCID: Skinner, Michael K.
Venue: Endocrinology
Publisher: The Endocrine Society
Published: 2006-06
Volume: 147
Issue: 6
Pages: s43-s49
ISSN: 0013-7227 (ISSN-L)
1945-7170
DOI: 10.1210/en.2005-1058
OpenAlex: W2054776840
Cited by: 455
References: 115
Citations by year: 2026: 3 · 2025: 7 · 2024: 11 · 2023: 10 · 2022: 11 · 2021: 20 · 2020: 17 · 2019: 17 · 2018: 15 · 2017: 29 · 2016: 24 · 2015: 27 · 2014: 34 · 2013: 35 · 2012: 38
FWCI: 25.12
Type: journal article
Language: en
Open access: closed
Locations: Endocrinology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Environmental Health Sciences (R01ES012974)
Topics: Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
Keywords: endocrine disruptors, transgenerational epigenetic inheritance, vinclozolin, male infertility, spermatogenic defects, subfertility, primordial germ cells, male germline, environmental toxins, epigenetic mechanisms
MeSH terms: Animals, Environmental Exposure, Environmental Pollutants, Biological Evolution, Humans, Mutation, Phenotype, Reproduction, Sex Differentiation, Epigenesis, Genetic, Endocrine Disruptors

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Epigenetic Transgenerational Actions of Endocrine Disruptors

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