The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
The Genetic Landscape of Type 2 Diabetes in Mice
Abstract
Inbred mouse strains provide genetic diversity comparable to that of the human population. Like humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse strains differ in the response of their critical physiological functions, such as insulin sensitivity, insulin secretion, beta-cell proliferation and survival, and fuel partitioning, to diet and obesity. Most of the critical genes underlying these differences have not been identified, although many loci have been mapped. The dramatic improvements in genomic and bioinformatics resources are accelerating the pace of gene discovery. This review describes how mouse genetics can be used to discover diabetes-related genes, summarizes how the mouse strains differ in their diabetes-related phenotypes, and describes several examples of how loci identified in the mouse may directly relate to human diabetes.
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Citations
Cites
Initial sequencing and comparative analysis of the mouse genome
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OBESE, A NEW MUTATION IN THE HOUSE MOUSE*
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Targeted disruption of the chop gene delays endoplasmic reticulum stress-mediated diabetes
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Cited by
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes.
Guilherme, A., Virbasius, J. V., Puri, V., & Czech, M. P. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2391 · Cited by 2,292
The use of animal models in diabetes research
King, A. J. (2012) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2012.01911.x · Cited by 1,303
Leptin and the endocrine control of energy balance
Friedman, J. M. (2019) · Nature Metabolism · doi:10.1038/s42255-019-0095-y · Cited by 661
Metabolic syndrome: from epidemiology to systems biology
Lusis, A. J., Attie, A. D., & Reue, K. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2468 · Cited by 344
Self-citationGlucose Metabolism In Vivo in Four Commonly Used Inbred Mouse Strains
Berglund, E. D., Li, C. Y., Poffenberger, G., Ayala, J. E., Fueger, P. T., Willis, S. E., Jewell, M. M., Powers, A. C., & Wasserman, D. H. (2008) · Diabetes · doi:10.2337/db07-1615 · Cited by 265
Metadata
- Authors
- Clee, S. M., & Attie, A. D.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 2007-02-01
- Volume
- 28
- Issue
- 1
- Pages
- 48-83
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2135190643
- Cited by
- 220
- References
- 18
- FWCI
- 6.87
- Type
- journal article
- Language
- en
- Open access
- closed
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